BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

145 related articles for article (PubMed ID: 18191165)

  • 1. Direct mitochondrial dysfunction precedes reactive oxygen species production in amiodarone-induced toxicity in human peripheral lung epithelial HPL1A cells.
    Nicolescu AC; Ji Y; Comeau JL; Hill BC; Takahashi T; Brien JF; Racz WJ; Massey TE
    Toxicol Appl Pharmacol; 2008 Mar; 227(3):370-9. PubMed ID: 18191165
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Aryl radical involvement in amiodarone-induced pulmonary toxicity: investigation of protection by spin-trapping nitrones.
    Nicolescu AC; Comeau JL; Hill BC; Bedard LL; Takahashi T; Brien JF; Racz WJ; Massey TE
    Toxicol Appl Pharmacol; 2007 Apr; 220(1):60-71. PubMed ID: 17316728
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Attenuation of amiodarone-induced pulmonary fibrosis by vitamin E is associated with suppression of transforming growth factor-beta1 gene expression but not prevention of mitochondrial dysfunction.
    Card JW; Racz WJ; Brien JF; Massey TE
    J Pharmacol Exp Ther; 2003 Jan; 304(1):277-83. PubMed ID: 12490602
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Evaluation of reactive oxygen species involvement in amiodarone pulmonary toxicity in vivo and in vitro.
    Leeder RG; Rafeiro E; Brien JF; Mandin CC; Massey TE
    J Biochem Toxicol; 1996; 11(3):147-60. PubMed ID: 9029274
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Mechanisms of amiodarone and desethylamiodarone cytotoxicity in nontransformed human peripheral lung epithelial cells.
    Mulder JE; Brien JF; Racz WJ; Takahashi T; Massey TE
    J Pharmacol Exp Ther; 2011 Feb; 336(2):551-9. PubMed ID: 21078785
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Cytotoxic interaction between amiodarone and desethylamiodarone in human peripheral lung epithelial cells.
    Roth FC; Mulder JE; Brien JF; Takahashi T; Massey TE
    Chem Biol Interact; 2013 Aug; 204(3):135-9. PubMed ID: 23707191
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Disruption of mitochondrial function and cellular ATP levels by amiodarone and N-desethylamiodarone in initiation of amiodarone-induced pulmonary cytotoxicity.
    Bolt MW; Card JW; Racz WJ; Brien JF; Massey TE
    J Pharmacol Exp Ther; 2001 Sep; 298(3):1280-9. PubMed ID: 11504831
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Differential effects of pirfenidone on acute pulmonary injury and ensuing fibrosis in the hamster model of amiodarone-induced pulmonary toxicity.
    Card JW; Racz WJ; Brien JF; Margolin SB; Massey TE
    Toxicol Sci; 2003 Sep; 75(1):169-80. PubMed ID: 12832656
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Comparison of the in vivo pulmonary toxicity of amiodarone and des-oxo-amiodarone in the hamster.
    Rafeiro E; Leeder RG; Brien JF; Kabalka GW; Chatla N; Massey TE
    Toxicol Appl Pharmacol; 1994 Aug; 127(2):275-81. PubMed ID: 8048071
    [TBL] [Abstract][Full Text] [Related]  

  • 10. HIV antiretroviral drug combination induces endothelial mitochondrial dysfunction and reactive oxygen species production, but not apoptosis.
    Jiang B; Hebert VY; Li Y; Mathis JM; Alexander JS; Dugas TR
    Toxicol Appl Pharmacol; 2007 Oct; 224(1):60-71. PubMed ID: 17669453
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Effects of vitamin E on cytotoxicity of amiodarone and N-desethylamiodarone in isolated hamster lung cells.
    Bolt MW; Racz WJ; Brien JF; Massey TE
    Toxicology; 2001 Sep; 166(3):109-18. PubMed ID: 11543907
    [TBL] [Abstract][Full Text] [Related]  

  • 12. TNF-alpha/cycloheximide-induced apoptosis in intestinal epithelial cells requires Rac1-regulated reactive oxygen species.
    Jin S; Ray RM; Johnson LR
    Am J Physiol Gastrointest Liver Physiol; 2008 Apr; 294(4):G928-37. PubMed ID: 18218673
    [TBL] [Abstract][Full Text] [Related]  

  • 13. A characterization of amiodarone-induced pulmonary toxicity in F344 rats and identification of surfactant protein-D as a potential biomarker for the development of the toxicity.
    Taylor MD; Van Dyke K; Bowman LL; Miles PR; Hubbs AF; Mason RJ; Shannon K; Reasor MJ
    Toxicol Appl Pharmacol; 2000 Sep; 167(3):182-90. PubMed ID: 10986009
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The role of CYP3A4 in amiodarone-associated toxicity on HepG2 cells.
    Zahno A; Brecht K; Morand R; Maseneni S; Török M; Lindinger PW; Krähenbühl S
    Biochem Pharmacol; 2011 Feb; 81(3):432-41. PubMed ID: 21070748
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Upstream reactive oxidative species (ROS) signals in exogenous oxidative stress-induced mitochondrial dysfunction.
    Lu M; Gong X
    Cell Biol Int; 2009 Jun; 33(6):658-64. PubMed ID: 19376252
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Involvement of mitochondrial alteration and reactive oxygen species generation in Taiwan cobra cardiotoxin-induced apoptotic death of human neuroblastoma SK-N-SH cells.
    Chen KC; Lin SR; Chang LS
    Toxicon; 2008 Aug; 52(2):361-8. PubMed ID: 18619991
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Amiodarone-induced disruption of hamster lung and liver mitochondrial function: lack of association with thiobarbituric acid-reactive substance production.
    Card JW; Lalonde BR; Rafeiro E; Tam AS; Racz WJ; Brien JF; Bray TM; Massey TE
    Toxicol Lett; 1998 Sep; 98(1-2):41-50. PubMed ID: 9776560
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Sanguinarine, a benzophenanthridine alkaloid, induces apoptosis in MDA-MB-231 human breast carcinoma cells through a reactive oxygen species-mediated mitochondrial pathway.
    Choi WY; Kim GY; Lee WH; Choi YH
    Chemotherapy; 2008; 54(4):279-87. PubMed ID: 18667818
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Cholestane-3beta,5alpha,6beta-triol-induced reactive oxygen species production promotes mitochondrial dysfunction in isolated mice liver mitochondria.
    Liu H; Wang T; Huang K
    Chem Biol Interact; 2009 May; 179(2-3):81-7. PubMed ID: 19121293
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Mechanisms of hepatocellular toxicity associated with dronedarone--a comparison to amiodarone.
    Felser A; Blum K; Lindinger PW; Bouitbir J; Krähenbühl S
    Toxicol Sci; 2013 Feb; 131(2):480-90. PubMed ID: 23135547
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.