These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

165 related articles for article (PubMed ID: 18193894)

  • 1. Probing conformational plasticity of the activation domain of trypsin: the role of glycine hinges.
    Gombos L; Kardos J; Patthy A; Medveczky P; Szilágyi L; Málnási-Csizmadia A; Gráf L
    Biochemistry; 2008 Feb; 47(6):1675-84. PubMed ID: 18193894
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Activating a zymogen without proteolytic processing: mutation of Lys15 and Asn194 activates trypsinogen.
    Pasternak A; Liu X; Lin TY; Hedstrom L
    Biochemistry; 1998 Nov; 37(46):16201-10. PubMed ID: 9819212
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Site directed mutagenesis at position 193 of human trypsin 4 alters the rate of conformational change during activation: role of local internal viscosity in protein dynamics.
    Tóth J; Simon Z; Medveczky P; Gombos L; Jelinek B; Szilágyi L; Gráf L; Málnási-Csizmadia A
    Proteins; 2007 Jun; 67(4):1119-27. PubMed ID: 17436323
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Structure of human pro-chymase: a model for the activating transition of granule-associated proteases.
    Reiling KK; Krucinski J; Miercke LJ; Raymond WW; Caughey GH; Stroud RM
    Biochemistry; 2003 Mar; 42(9):2616-24. PubMed ID: 12614156
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The effects of amino acid replacements of glycine 20 on conformational stability and catalysis of staphylococcal nuclease.
    Feng Y; Huang S; Zhang W; Zeng Z; Zou X; Zhong L; Peng J; Jing G
    Biochimie; 2004 Dec; 86(12):893-901. PubMed ID: 15667939
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Entropy effects on protein hinges: the reaction catalyzed by triosephosphate isomerase.
    Xiang J; Jung JY; Sampson NS
    Biochemistry; 2004 Sep; 43(36):11436-45. PubMed ID: 15350130
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Role of active-site residues of dispersin B, a biofilm-releasing beta-hexosaminidase from a periodontal pathogen, in substrate hydrolysis.
    Manuel SG; Ragunath C; Sait HB; Izano EA; Kaplan JB; Ramasubbu N
    FEBS J; 2007 Nov; 274(22):5987-99. PubMed ID: 17949435
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Activation loop 3 and the 170 loop interact in the active conformation of coagulation factor VIIa.
    Persson E; Olsen OH
    FEBS J; 2009 Jun; 276(11):3099-109. PubMed ID: 19490111
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The utility of molecular dynamics simulations for understanding site-directed mutagenesis of glycine residues in biotin carboxylase.
    Bordelon T; Nilsson Lill SO; Waldrop GL
    Proteins; 2009 Mar; 74(4):808-19. PubMed ID: 18704941
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The role of Tyr71 in Streptomyces trypsin on the recognition mechanism of structural protein substrates.
    Uesugi Y; Usuki H; Iwabuchi M; Hatanaka T
    FEBS J; 2009 Oct; 276(19):5634-46. PubMed ID: 19725878
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Backbone flexibility, conformational change, and catalysis in a phosphohexomutase from Pseudomonas aeruginosa.
    Schramm AM; Mehra-Chaudhary R; Furdui CM; Beamer LJ
    Biochemistry; 2008 Sep; 47(35):9154-62. PubMed ID: 18690721
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Hydrophobic interactions control zymogen activation in the trypsin family of serine proteases.
    Hedstrom L; Lin TY; Fast W
    Biochemistry; 1996 Apr; 35(14):4515-23. PubMed ID: 8605201
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Probing catalytic hinge bending motions in thermolysin-like proteases by glycine --> alanine mutations.
    Veltman OR; Eijsink VG; Vriend G; de Kreij A; Venema G; Van den Burg B
    Biochemistry; 1998 Apr; 37(15):5305-11. PubMed ID: 9548762
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Prevention of beta strand movement into a zymogen-like position does not confer higher activity to coagulation factor VIIa.
    Olsen OH; Nielsen PF; Persson E
    Biochemistry; 2004 Nov; 43(44):14096-103. PubMed ID: 15518559
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Effects of serpin binding on the target proteinase: global stabilization, localized increased structural flexibility, and conserved hydrogen bonding at the active site.
    Kaslik G; Kardos J; Szabó E; Szilágyi L; Závodszky P; Westler WM; Markley JL; Gráf L
    Biochemistry; 1997 May; 36(18):5455-64. PubMed ID: 9154928
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Homology modeling of the structure of tobacco acetohydroxy acid synthase and examination of the active site by site-directed mutagenesis.
    Le DT; Yoon MY; Kim YT; Choi JD
    Biochem Biophys Res Commun; 2004 May; 317(3):930-8. PubMed ID: 15081429
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Mutational analysis of conserved glycine residues 142, 143 and 146 reveals Gly(142) is critical for tetramerization of CTP synthase from Escherichia coli.
    Lunn FA; Macleod TJ; Bearne SL
    Biochem J; 2008 May; 412(1):113-21. PubMed ID: 18260824
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Modulation of human cytidine deaminase by specific aminoacids involved in the intersubunit interactions.
    Vincenzetti S; Quadrini B; Mariani P; De Sanctis G; Cammertoni N; Polzonetti V; Pucciarelli S; Natalini P; Vita A
    Proteins; 2008 Jan; 70(1):144-56. PubMed ID: 17640070
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Trypsinogen-trypsin transition: a molecular dynamics study of induced conformational change in the activation domain.
    Brünger AT; Huber R; Karplus M
    Biochemistry; 1987 Aug; 26(16):5153-62. PubMed ID: 3663651
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Probing the active site of Corynebacterium callunae starch phosphorylase through the characterization of wild-type and His334-->Gly mutant enzymes.
    Schwarz A; Brecker L; Nidetzky B
    FEBS J; 2007 Oct; 274(19):5105-15. PubMed ID: 17803683
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.