BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

191 related articles for article (PubMed ID: 18194192)

  • 1. Tubulin-perturbing naphthoquinone spiroketals.
    Balachandran R; Hopkins TD; Thomas CA; Wipf P; Day BW
    Chem Biol Drug Des; 2008 Feb; 71(2):117-24. PubMed ID: 18194192
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Quinolone analogue inhibits tubulin polymerization and induces apoptosis via Cdk1-involved signaling pathways.
    Chen YC; Lu PH; Pan SL; Teng CM; Kuo SC; Lin TP; Ho YF; Huang YC; Guh JH
    Biochem Pharmacol; 2007 Jun; 74(1):10-9. PubMed ID: 17475221
    [TBL] [Abstract][Full Text] [Related]  

  • 3. A-204197, a new tubulin-binding agent with antimitotic activity in tumor cell lines resistant to known microtubule inhibitors.
    Tahir SK; Han EK; Credo B; Jae HS; Pietenpol JA; Scatena CD; Wu-Wong JR; Frost D; Sham H; Rosenberg SH; Ng SC
    Cancer Res; 2001 Jul; 61(14):5480-5. PubMed ID: 11454695
    [TBL] [Abstract][Full Text] [Related]  

  • 4. SPIKET and COBRA compounds as novel tubulin modulators with potent anticancer activity.
    Uckun FM; Mao C; Jan ST; Huang H; Vassilev AO; Sudbeck EA; Navara CS; Narla RK
    Curr Opin Investig Drugs; 2000 Oct; 1(2):252-6. PubMed ID: 11249582
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Identification of novel antimitotic agents acting at the tubulin level by computer-assisted evaluation of differential cytotoxicity data.
    Paull KD; Lin CM; Malspeis L; Hamel E
    Cancer Res; 1992 Jul; 52(14):3892-900. PubMed ID: 1617665
    [TBL] [Abstract][Full Text] [Related]  

  • 6. 9-Benzylidene-naphtho[2,3-b]thiophen-4-ones as novel antimicrotubule agents-synthesis, antiproliferative activity, and inhibition of tubulin polymerization.
    Zuse A; Schmidt P; Baasner S; Böhm KJ; Müller K; Gerlach M; Günther EG; Unger E; Prinz H
    J Med Chem; 2006 Dec; 49(26):7816-25. PubMed ID: 17181164
    [TBL] [Abstract][Full Text] [Related]  

  • 7. 2-aroylindoles, a novel class of potent, orally active small molecule tubulin inhibitors.
    Beckers T; Reissmann T; Schmidt M; Burger AM; Fiebig HH; Vanhoefer U; Pongratz H; Hufsky H; Hockemeyer J; Frieser M; Mahboobi S
    Cancer Res; 2002 Jun; 62(11):3113-9. PubMed ID: 12036922
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Mechanism of apicidin-induced cell cycle arrest and apoptosis in Ishikawa human endometrial cancer cells.
    Ahn MY; Lee J; Na YJ; Choi WS; Lee BM; Kang KW; Kim HS
    Chem Biol Interact; 2009 May; 179(2-3):169-77. PubMed ID: 19070610
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Antimitotic actions of a novel analog of the fungal metabolite palmarumycin CP1.
    Lazo JS; Tamura K; Vogt A; Jung JK; Rodriguez S; Balachandran R; Day BW; Wipf P
    J Pharmacol Exp Ther; 2001 Feb; 296(2):364-71. PubMed ID: 11160619
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Isoindolo[2,1-a]quinoxaline derivatives, novel potent antitumor agents with dual inhibition of tubulin polymerization and topoisomerase I.
    Diana P; Martorana A; Barraja P; Montalbano A; Dattolo G; Cirrincione G; Dall'acqua F; Salvador A; Vedaldi D; Basso G; Viola G
    J Med Chem; 2008 Apr; 51(8):2387-99. PubMed ID: 18366178
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Investigation of anti-tumor mechanisms of K2154: characterization of tubulin isotypes, mitotic arrest and apoptotic machinery.
    Lu PH; Kung FL; Kuo SC; Chueh SC; Guh JH
    Naunyn Schmiedebergs Arch Pharmacol; 2006 Dec; 374(3):223-33. PubMed ID: 17102938
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Novel benzylidene-9(10H)-anthracenones as highly active antimicrotubule agents. Synthesis, antiproliferative activity, and inhibition of tubulin polymerization.
    Prinz H; Ishii Y; Hirano T; Stoiber T; Camacho Gomez JA; Schmidt P; Düssmann H; Burger AM; Prehn JH; Günther EG; Unger E; Umezawa K
    J Med Chem; 2003 Jul; 46(15):3382-94. PubMed ID: 12852768
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Synthesis and biological evaluation of 2-amino-3-(3',4',5'-trimethoxybenzoyl)-5-aryl thiophenes as a new class of potent antitubulin agents.
    Romagnoli R; Baraldi PG; Pavani MG; Tabrizi MA; Preti D; Fruttarolo F; Piccagli L; Jung MK; Hamel E; Borgatti M; Gambari R
    J Med Chem; 2006 Jun; 49(13):3906-15. PubMed ID: 16789746
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The natural naphthoquinone plumbagin exhibits antiproliferative activity and disrupts the microtubule network through tubulin binding.
    Acharya BR; Bhattacharyya B; Chakrabarti G
    Biochemistry; 2008 Jul; 47(30):7838-45. PubMed ID: 18597479
    [TBL] [Abstract][Full Text] [Related]  

  • 15. MPC-6827: a small-molecule inhibitor of microtubule formation that is not a substrate for multidrug resistance pumps.
    Kasibhatla S; Baichwal V; Cai SX; Roth B; Skvortsova I; Skvortsov S; Lukas P; English NM; Sirisoma N; Drewe J; Pervin A; Tseng B; Carlson RO; Pleiman CM
    Cancer Res; 2007 Jun; 67(12):5865-71. PubMed ID: 17575155
    [TBL] [Abstract][Full Text] [Related]  

  • 16. A new cytotoxic spiroketal from the myxobacterium Sorangium cellulosum.
    Kwak JH; Ahn JW
    Arch Pharm Res; 2009 Jun; 32(6):841-4. PubMed ID: 19557360
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The synthetic compound CC-5079 is a potent inhibitor of tubulin polymerization and tumor necrosis factor-alpha production with antitumor activity.
    Zhang LH; Wu L; Raymon HK; Chen RS; Corral L; Shirley MA; Narla RK; Gamez J; Muller GW; Stirling DI; Bartlett JB; Schafer PH; Payvandi F
    Cancer Res; 2006 Jan; 66(2):951-9. PubMed ID: 16424030
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Design, synthesis, and biological evaluation of thiophene analogues of chalcones.
    Romagnoli R; Baraldi PG; Carrion MD; Cara CL; Cruz-Lopez O; Preti D; Tolomeo M; Grimaudo S; Di Cristina A; Zonta N; Balzarini J; Brancale A; Sarkar T; Hamel E
    Bioorg Med Chem; 2008 May; 16(10):5367-76. PubMed ID: 18440234
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Inhibitors and promoters of tubulin polymerization: synthesis and biological evaluation of chalcones and related dienones as potential anticancer agents.
    Dyrager C; Wickström M; Fridén-Saxin M; Friberg A; Dahlén K; Wallén EA; Gullbo J; Grøtli M; Luthman K
    Bioorg Med Chem; 2011 Apr; 19(8):2659-65. PubMed ID: 21459004
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Laulimalide and synthetic laulimalide analogues are synergistic with paclitaxel and 2-methoxyestradiol.
    Clark EA; Hills PM; Davidson BS; Wender PA; Mooberry SL
    Mol Pharm; 2006; 3(4):457-67. PubMed ID: 16889440
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.