BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

191 related articles for article (PubMed ID: 18194192)

  • 21. Natural product based inhibitors of the thioredoxin-thioredoxin reductase system.
    Wipf P; Lynch SM; Birmingham A; Tamayo G; Jiménez A; Campos N; Powis G
    Org Biomol Chem; 2004 Jun; 2(11):1651-8. PubMed ID: 15162219
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Cytotoxic activity and cytostatic mechanism of novel 2-arylbenzo[b]furans.
    Yang H; Pang JY; Cai YC; Xu ZL; Xian LJ
    J Pharm Pharmacol; 2006 Sep; 58(9):1281-7. PubMed ID: 16945188
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Tubulin assembly, taxoid site binding, and cellular effects of the microtubule-stabilizing agent dictyostatin.
    Madiraju C; Edler MC; Hamel E; Raccor BS; Balachandran R; Zhu G; Giuliano KA; Vogt A; Shin Y; Fournier JH; Fukui Y; Brückner AM; Curran DP; Day BW
    Biochemistry; 2005 Nov; 44(45):15053-63. PubMed ID: 16274252
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Sulfonate derivatives of naphtho[2,3-b]thiophen-4(9H)-one and 9(10H)-anthracenone as highly active antimicrotubule agents. Synthesis, antiproliferative activity, and inhibition of tubulin polymerization.
    Zuse A; Schmidt P; Baasner S; Böhm KJ; Müller K; Gerlach M; Günther EG; Unger E; Prinz H
    J Med Chem; 2007 Nov; 50(24):6059-66. PubMed ID: 17973361
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Dietary antioxidant curcumin inhibits microtubule assembly through tubulin binding.
    Gupta KK; Bharne SS; Rathinasamy K; Naik NR; Panda D
    FEBS J; 2006 Dec; 273(23):5320-32. PubMed ID: 17069615
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Cyclostreptin (FR182877), an antitumor tubulin-polymerizing agent deficient in enhancing tubulin assembly despite its high affinity for the taxoid site.
    Edler MC; Buey RM; Gussio R; Marcus AI; Vanderwal CD; Sorensen EJ; Díaz JF; Giannakakou P; Hamel E
    Biochemistry; 2005 Aug; 44(34):11525-38. PubMed ID: 16114889
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Novel diarylsulfonylurea derivatives as potent antimitotic agents.
    Kim S; Park JH; Koo SY; Kim JI; Kim MH; Kim JE; Jo K; Choi HG; Lee SB; Jung SH
    Bioorg Med Chem Lett; 2004 Dec; 14(24):6075-8. PubMed ID: 15546733
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Biological evaluation of 2,3-dichloro-5,8-dimethoxy-1,4-naphthoquinone as an anti-breast cancer agent.
    Kanaan YM; Das JR; Bakare O; Enwerem NM; Berhe S; Beyene D; Williams V; Zhou Y; Copeland RL
    Anticancer Res; 2009 Jan; 29(1):191-9. PubMed ID: 19331150
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Phenylimino-10H-anthracen-9-ones as novel antimicrotubule agents-synthesis, antiproliferative activity and inhibition of tubulin polymerization.
    Prinz H; Schmidt P; Böhm KJ; Baasner S; Müller K; Gerlach M; Günther EG; Unger E
    Bioorg Med Chem; 2011 Jul; 19(14):4183-91. PubMed ID: 21705223
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Rhabdoid tumor growth is inhibited by flavopiridol.
    Smith ME; Cimica V; Chinni S; Challagulla K; Mani S; Kalpana GV
    Clin Cancer Res; 2008 Jan; 14(2):523-32. PubMed ID: 18223228
    [TBL] [Abstract][Full Text] [Related]  

  • 31. 4- and 5-aroylindoles as novel classes of potent antitubulin agents.
    Liou JP; Wu CY; Hsieh HP; Chang CY; Chen CM; Kuo CC; Chang JY
    J Med Chem; 2007 Sep; 50(18):4548-52. PubMed ID: 17685504
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Inhibition of thioredoxin reductase by mansonone F analogues: Implications for anticancer activity.
    Liu Z; Huang SL; Li MM; Huang ZS; Lee KS; Gu LQ
    Chem Biol Interact; 2009 Jan; 177(1):48-57. PubMed ID: 18822278
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Vitamin K3 disrupts the microtubule networks by binding to tubulin: a novel mechanism of its antiproliferative activity.
    Acharya BR; Choudhury D; Das A; Chakrabarti G
    Biochemistry; 2009 Jul; 48(29):6963-74. PubMed ID: 19527023
    [TBL] [Abstract][Full Text] [Related]  

  • 34. [(2-Phenylindol-3-yl)methylene]propanedinitriles inhibit the growth of breast cancer cells by cell cycle arrest in G(2)/M phase and apoptosis.
    Pojarová M; Kaufmann D; Gastpar R; Nishino T; Reszka P; Bednarski PJ; von Angerer E
    Bioorg Med Chem; 2007 Dec; 15(23):7368-79. PubMed ID: 17889547
    [TBL] [Abstract][Full Text] [Related]  

  • 35. A novel histone deacetylase inhibitor, CG0006, induces cell death through both extrinsic and intrinsic apoptotic pathways.
    Hwang JJ; Kim YS; Kim MJ; Jang S; Lee JH; Choi J; Ro S; Hyun YL; Lee JS; Kim CS
    Anticancer Drugs; 2009 Oct; 20(9):815-21. PubMed ID: 19644355
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Generation of ligand-based pharmacophore model and virtual screening for identification of novel tubulin inhibitors with potent anticancer activity.
    Chiang YK; Kuo CC; Wu YS; Chen CT; Coumar MS; Wu JS; Hsieh HP; Chang CY; Jseng HY; Wu MH; Leou JS; Song JS; Chang JY; Lyu PC; Chao YS; Wu SY
    J Med Chem; 2009 Jul; 52(14):4221-33. PubMed ID: 19507860
    [TBL] [Abstract][Full Text] [Related]  

  • 37. XN05, a novel synthesized microtubule inhibitor, exhibits potent activity against human carcinoma cells in vitro.
    Wu R; Ding W; Liu T; Zhu H; Hu Y; Yang B; He Q
    Cancer Lett; 2009 Nov; 285(1):13-22. PubMed ID: 19647933
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Novel tubulin-polymerization inhibitor derived from thalidomide directly induces apoptosis in human multiple myeloma cells: possible anti-myeloma mechanism of thalidomide.
    Iguchi T; Yachide-Noguchi T; Hashimoto Y; Nakazato S; Sagawa M; Ikeda Y; Kizaki M
    Int J Mol Med; 2008 Feb; 21(2):163-8. PubMed ID: 18204782
    [TBL] [Abstract][Full Text] [Related]  

  • 39. 1,5-Disubstituted 1,2,3-triazoles as cis-restricted analogues of combretastatin A-4: Synthesis, molecular modeling and evaluation as cytotoxic agents and inhibitors of tubulin.
    Odlo K; Hentzen J; dit Chabert JF; Ducki S; Gani OA; Sylte I; Skrede M; Flørenes VA; Hansen TV
    Bioorg Med Chem; 2008 May; 16(9):4829-38. PubMed ID: 18396050
    [TBL] [Abstract][Full Text] [Related]  

  • 40. R-253 disrupts microtubule networks in multiple tumor cell lines.
    Gururaja TL; Goff D; Kinoshita T; Goldstein E; Yung S; McLaughlin J; Pali E; Huang J; Singh R; Daniel-Issakani S; Hitoshi Y; Cooper RD; Payan DG
    Clin Cancer Res; 2006 Jun; 12(12):3831-42. PubMed ID: 16778111
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 10.