BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

218 related articles for article (PubMed ID: 18195096)

  • 1. Prospective tracing of MLL-FRYL clone with low MEIS1 expression from emergence during neuroblastoma treatment to diagnosis of myelodysplastic syndrome.
    Robinson BW; Cheung NK; Kolaris CP; Jhanwar SC; Choi JK; Osheroff N; Felix CA
    Blood; 2008 Apr; 111(7):3802-12. PubMed ID: 18195096
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Near-precise interchromosomal recombination and functional DNA topoisomerase II cleavage sites at MLL and AF-4 genomic breakpoints in treatment-related acute lymphoblastic leukemia with t(4;11) translocation.
    Lovett BD; Lo Nigro L; Rappaport EF; Blair IA; Osheroff N; Zheng N; Megonigal MD; Williams WR; Nowell PC; Felix CA
    Proc Natl Acad Sci U S A; 2001 Aug; 98(17):9802-7. PubMed ID: 11493704
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Detection of leukemia-associated MLL-GAS7 translocation early during chemotherapy with DNA topoisomerase II inhibitors.
    Megonigal MD; Cheung NK; Rappaport EF; Nowell PC; Wilson RB; Jones DH; Addya K; Leonard DG; Kushner BH; Williams TM; Lange BJ; Felix CA
    Proc Natl Acad Sci U S A; 2000 Mar; 97(6):2814-9. PubMed ID: 10706619
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Translocation (4;11)(p12;q23) with rearrangement of FRYL and MLL in therapy-related acute myeloid leukemia.
    Sait SN; Claydon MA; Conroy JM; Nowak NJ; Barcos M; Baer MR
    Cancer Genet Cytogenet; 2007 Sep; 177(2):143-6. PubMed ID: 17854671
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Clinical significance of MLL-AF4 fusion transcript expression in the absence of a cytogenetically detectable t(4;11)(q21;q23) chromosomal translocation.
    Uckun FM; Herman-Hatten K; Crotty ML; Sensel MG; Sather HN; Tuel-Ahlgren L; Sarquis MB; Bostrom B; Nachman JB; Steinherz PG; Gaynon PS; Heerema N
    Blood; 1998 Aug; 92(3):810-21. PubMed ID: 9680349
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Reciprocal DNA topoisomerase II cleavage events at 5'-TATTA-3' sequences in MLL and AF-9 create homologous single-stranded overhangs that anneal to form der(11) and der(9) genomic breakpoint junctions in treatment-related AML without further processing.
    Whitmarsh RJ; Saginario C; Zhuo Y; Hilgenfeld E; Rappaport EF; Megonigal MD; Carroll M; Liu M; Osheroff N; Cheung NK; Slater DJ; Ried T; Knutsen T; Blair IA; Felix CA
    Oncogene; 2003 Nov; 22(52):8448-59. PubMed ID: 14627986
    [TBL] [Abstract][Full Text] [Related]  

  • 7. t(3;11) translocation in treatment-related acute myeloid leukemia fuses MLL with the GMPS (GUANOSINE 5' MONOPHOSPHATE SYNTHETASE) gene.
    Pegram LD; Megonigal MD; Lange BJ; Nowell PC; Rowley JD; Rappaport EF; Felix CA
    Blood; 2000 Dec; 96(13):4360-2. PubMed ID: 11110714
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Expression of HOX genes in acute leukemia cell lines with and without MLL translocations.
    Quentmeier H; Dirks WG; Macleod RA; Reinhardt J; Zaborski M; Drexler HG
    Leuk Lymphoma; 2004 Mar; 45(3):567-74. PubMed ID: 15160920
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Etoposide metabolites enhance DNA topoisomerase II cleavage near leukemia-associated MLL translocation breakpoints.
    Lovett BD; Strumberg D; Blair IA; Pang S; Burden DA; Megonigal MD; Rappaport EF; Rebbeck TR; Osheroff N; Pommier YG; Felix CA
    Biochemistry; 2001 Feb; 40(5):1159-70. PubMed ID: 11170441
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Molecular emergence of acute myeloid leukemia during treatment for acute lymphoblastic leukemia.
    Blanco JG; Dervieux T; Edick MJ; Mehta PK; Rubnitz JE; Shurtleff S; Raimondi SC; Behm FG; Pui CH; Relling MV
    Proc Natl Acad Sci U S A; 2001 Aug; 98(18):10338-43. PubMed ID: 11526240
    [TBL] [Abstract][Full Text] [Related]  

  • 11. MLL-SEPTIN6 fusion recurs in novel translocation of chromosomes 3, X, and 11 in infant acute myelomonocytic leukaemia and in t(X;11) in infant acute myeloid leukaemia, and MLL genomic breakpoint in complex MLL-SEPTIN6 rearrangement is a DNA topoisomerase II cleavage site.
    Slater DJ; Hilgenfeld E; Rappaport EF; Shah N; Meek RG; Williams WR; Lovett BD; Osheroff N; Autar RS; Ried T; Felix CA
    Oncogene; 2002 Jul; 21(30):4706-14. PubMed ID: 12096348
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The broken MLL gene is frequently located outside the inherent chromosome territory in human lymphoid cells treated with DNA topoisomerase II poison etoposide.
    Glukhov SI; Rubtsov MA; Alexeyevsky DA; Alexeevski AV; Razin SV; Iarovaia OV
    PLoS One; 2013; 8(9):e75871. PubMed ID: 24086652
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Emergence of two unrelated clones in acute myeloid leukemia with MLL-SEPT9 fusion transcript.
    Saito H; Otsubo K; Kakimoto A; Komatsu N; Ohsaka A
    Cancer Genet Cytogenet; 2010 Sep; 201(2):111-5. PubMed ID: 20682395
    [TBL] [Abstract][Full Text] [Related]  

  • 14. t(10;11)-acute leukemias with MLL-AF10 and MLL-ABI1 chimeric transcripts: specific expression patterns of ABI1 gene in leukemia and solid tumor cell lines.
    Shibuya N; Taki T; Mugishima H; Chin M; Tsuchida M; Sako M; Kawa K; Ishii E; Miura I; Yanagisawa M; Hayashi Y
    Genes Chromosomes Cancer; 2001 Sep; 32(1):1-10. PubMed ID: 11477655
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Secondary leukemias induced by topoisomerase-targeted drugs.
    Felix CA
    Biochim Biophys Acta; 1998 Oct; 1400(1-3):233-55. PubMed ID: 9748598
    [TBL] [Abstract][Full Text] [Related]  

  • 16. PBX3 and MEIS1 Cooperate in Hematopoietic Cells to Drive Acute Myeloid Leukemias Characterized by a Core Transcriptome of the MLL-Rearranged Disease.
    Li Z; Chen P; Su R; Hu C; Li Y; Elkahloun AG; Zuo Z; Gurbuxani S; Arnovitz S; Weng H; Wang Y; Li S; Huang H; Neilly MB; Wang GG; Jiang X; Liu PP; Jin J; Chen J
    Cancer Res; 2016 Feb; 76(3):619-29. PubMed ID: 26747896
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Novel variant form of t(11;22)(q23;q13)/MLL-EP300 fusion transcript in the evolution of an acute myeloid leukemia with myelodysplasia-related changes.
    Duhoux FP; De Wilde S; Ameye G; Bahloula K; Medves S; Légé G; Libouton JM; Demoulin JB; A Poirel H
    Leuk Res; 2011 Mar; 35(3):e18-20. PubMed ID: 20980053
    [No Abstract]   [Full Text] [Related]  

  • 18. Grist for the MLL: how do MLL oncogenic fusion proteins generate leukemia stem cells?
    Somervaille TC; Cleary ML
    Int J Hematol; 2010 Jun; 91(5):735-41. PubMed ID: 20454944
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Molecular analysis of 13 cases of MLL/11q23 secondary acute leukemia and identification of topoisomerase II consensus-binding sequences near the chromosomal breakpoint of a secondary leukemia with the t(4;11).
    Domer PH; Head DR; Renganathan N; Raimondi SC; Yang E; Atlas M
    Leukemia; 1995 Aug; 9(8):1305-12. PubMed ID: 7643617
    [TBL] [Abstract][Full Text] [Related]  

  • 20. A role for MEIS1 in MLL-fusion gene leukemia.
    Kumar AR; Li Q; Hudson WA; Chen W; Sam T; Yao Q; Lund EA; Wu B; Kowal BJ; Kersey JH
    Blood; 2009 Feb; 113(8):1756-8. PubMed ID: 19109563
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.