358 related articles for article (PubMed ID: 18198825)
1. 2-Oxotetrahydroquinoline-based antimalarials with high potency and metabolic stability.
Bulbule VJ; Rivas K; Verlinde CL; Van Voorhis WC; Gelb MH
J Med Chem; 2008 Feb; 51(3):384-7. PubMed ID: 18198825
[TBL] [Abstract][Full Text] [Related]
2. Protein farnesyltransferase inhibitors exhibit potent antimalarial activity.
Nallan L; Bauer KD; Bendale P; Rivas K; Yokoyama K; Hornéy CP; Pendyala PR; Floyd D; Lombardo LJ; Williams DK; Hamilton A; Sebti S; Windsor WT; Weber PC; Buckner FS; Chakrabarti D; Gelb MH; Van Voorhis WC
J Med Chem; 2005 Jun; 48(11):3704-13. PubMed ID: 15916422
[TBL] [Abstract][Full Text] [Related]
3. Second generation tetrahydroquinoline-based protein farnesyltransferase inhibitors as antimalarials.
Bendale P; Olepu S; Suryadevara PK; Bulbule V; Rivas K; Nallan L; Smart B; Yokoyama K; Ankala S; Pendyala PR; Floyd D; Lombardo LJ; Williams DK; Buckner FS; Chakrabarti D; Verlinde CL; Van Voorhis WC; Gelb MH
J Med Chem; 2007 Sep; 50(19):4585-605. PubMed ID: 17722901
[TBL] [Abstract][Full Text] [Related]
4. Structure-activity relationships amongst 4-position quinoline methanol antimalarials that inhibit the growth of drug sensitive and resistant strains of Plasmodium falciparum.
Milner E; McCalmont W; Bhonsle J; Caridha D; Carroll D; Gardner S; Gerena L; Gettayacamin M; Lanteri C; Luong T; Melendez V; Moon J; Roncal N; Sousa J; Tungtaeng A; Wipf P; Dow G
Bioorg Med Chem Lett; 2010 Feb; 20(4):1347-51. PubMed ID: 20097070
[TBL] [Abstract][Full Text] [Related]
5. Synthesis and antimalarial activity of carbamate and amide derivatives of 4-anilinoquinoline.
Delarue-Cochin S; Grellier P; Maes L; Mouray E; Sergheraert C; Melnyk P
Eur J Med Chem; 2008 Oct; 43(10):2045-55. PubMed ID: 18226428
[TBL] [Abstract][Full Text] [Related]
6. Discovery of a rhodanine class of compounds as inhibitors of Plasmodium falciparum enoyl-acyl carrier protein reductase.
Kumar G; Parasuraman P; Sharma SK; Banerjee T; Karmodiya K; Surolia N; Surolia A
J Med Chem; 2007 May; 50(11):2665-75. PubMed ID: 17477517
[TBL] [Abstract][Full Text] [Related]
7. Design, synthesis, and structure-activity relationship studies of 4-quinolinyl- and 9-acrydinylhydrazones as potent antimalarial agents.
Fattorusso C; Campiani G; Kukreja G; Persico M; Butini S; Romano MP; Altarelli M; Ros S; Brindisi M; Savini L; Novellino E; Nacci V; Fattorusso E; Parapini S; Basilico N; Taramelli D; Yardley V; Croft S; Borriello M; Gemma S
J Med Chem; 2008 Mar; 51(5):1333-43. PubMed ID: 18278859
[TBL] [Abstract][Full Text] [Related]
8. Non-thiol farnesyltransferase inhibitors: N-(4-aminoacylamino-3-benzoylphenyl)-3-[5-(4-nitrophenyl)-2 furyl]acrylic acid amides and their antimalarial activity.
Kettler K; Wiesner J; Silber K; Haebel P; Ortmann R; Sattler I; Dahse HM; Jomaa H; Klebe G; Schlitzer M
Eur J Med Chem; 2005 Jan; 40(1):93-101. PubMed ID: 15642414
[TBL] [Abstract][Full Text] [Related]
9. Design and synthesis of piperidine farnesyltransferase inhibitors with reduced glucuronidation potential.
Tanaka R; Rubio A; Harn NK; Gernert D; Grese TA; Eishima J; Hara M; Yoda N; Ohashi R; Kuwabara T; Soga S; Akinaga S; Nara S; Kanda Y
Bioorg Med Chem; 2007 Feb; 15(3):1363-82. PubMed ID: 17127066
[TBL] [Abstract][Full Text] [Related]
10. 4-anilinoquinoline triazines: a novel class of hybrid antimalarial agents.
Kumar A; Srivastava K; Kumar SR; Siddiqi MI; Puri SK; Sexana JK; Chauhan PM
Eur J Med Chem; 2011 Feb; 46(2):676-90. PubMed ID: 21194812
[TBL] [Abstract][Full Text] [Related]
11. Development of benzophenone-based farnesyltransferase inhibitors as novel antimalarials.
Kohring K; Wiesner J; Altenkämper M; Sakowski J; Silber K; Hillebrecht A; Haebel P; Dahse HM; Ortmann R; Jomaa H; Klebe G; Schlitzer M
ChemMedChem; 2008 Aug; 3(8):1217-31. PubMed ID: 18470859
[TBL] [Abstract][Full Text] [Related]
12. Bisquinolines. 2. Antimalarial N,N-bis(7-chloroquinolin-4-yl)heteroalkanediamines.
Vennerstrom JL; Ager AL; Dorn A; Andersen SL; Gerena L; Ridley RG; Milhous WK
J Med Chem; 1998 Oct; 41(22):4360-4. PubMed ID: 9784111
[TBL] [Abstract][Full Text] [Related]
13. New 4-aminoquinoline Mannich base antimalarials. 1. Effect of an alkyl substituent in the 5'-position of the 4'-hydroxyanilino side chain.
Raynes KJ; Stocks PA; O'Neill PM; Park BK; Ward SA
J Med Chem; 1999 Jul; 42(15):2747-51. PubMed ID: 10425085
[TBL] [Abstract][Full Text] [Related]
14. In vitro and in vivo antimalarial activity of peptidomimetic protein farnesyltransferase inhibitors with improved membrane permeability.
Carrico D; Ohkanda J; Kendrick H; Yokoyama K; Blaskovich MA; Bucher CJ; Buckner FS; Van Voorhis WC; Chakrabarti D; Croft SL; Gelb MH; Sebti SM; Hamilton AD
Bioorg Med Chem; 2004 Dec; 12(24):6517-26. PubMed ID: 15556768
[TBL] [Abstract][Full Text] [Related]
15. Novel N-(4-Piperidinyl)benzamide antimalarials with mammalian protein farnesyltransferase inhibitory activity.
Ryckebusch A; Gilleron P; Millet R; Houssin R; Lemoine A; Pommery N; Grellier P; Sergheraert C; Hénichart JP
Chem Pharm Bull (Tokyo); 2005 Oct; 53(10):1324-6. PubMed ID: 16204993
[TBL] [Abstract][Full Text] [Related]
16. Synthesis and antiplasmodial activity of aminoalkylamino-substituted neocryptolepine derivatives.
El Sayed I; Van der Veken P; Steert K; Dhooghe L; Hostyn S; Van Baelen G; Lemière G; Maes BU; Cos P; Maes L; Joossens J; Haemers A; Pieters L; Augustyns K
J Med Chem; 2009 May; 52(9):2979-88. PubMed ID: 19364118
[TBL] [Abstract][Full Text] [Related]
17. Synthesis and in vitro and in vivo antimalarial activity of N1-(7-chloro-4-quinolyl)-1,4-bis(3-aminopropyl)piperazine derivatives.
Ryckebusch A; Deprez-Poulain R; Maes L; Debreu-Fontaine MA; Mouray E; Grellier P; Sergheraert C
J Med Chem; 2003 Feb; 46(4):542-57. PubMed ID: 12570376
[TBL] [Abstract][Full Text] [Related]
18. Probing the role of the covalent linkage of ferrocene into a chloroquine template.
Biot C; Daher W; Ndiaye CM; Melnyk P; Pradines B; Chavain N; Pellet A; Fraisse L; Pelinski L; Jarry C; Brocard J; Khalife J; Forfar-Bares I; Dive D
J Med Chem; 2006 Jul; 49(15):4707-14. PubMed ID: 16854077
[TBL] [Abstract][Full Text] [Related]
19. Synthesis, biological activity, and X-ray crystal structural analysis of diaryl ether inhibitors of malarial enoyl acyl carrier protein reductase. Part 1: 4'-substituted triclosan derivatives.
Freundlich JS; Anderson JW; Sarantakis D; Shieh HM; Yu M; Valderramos JC; Lucumi E; Kuo M; Jacobs WR; Fidock DA; Schiehser GA; Jacobus DP; Sacchettini JC
Bioorg Med Chem Lett; 2005 Dec; 15(23):5247-52. PubMed ID: 16198563
[TBL] [Abstract][Full Text] [Related]
20. Docking studies and development of novel 5-heteroarylamino-2,4-diamino-8-chloropyrimido-[4,5-b]quinolines as potential antimalarials.
Joshi AA; Viswanathan CL
Bioorg Med Chem Lett; 2006 May; 16(10):2613-7. PubMed ID: 16516468
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
