BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

651 related articles for article (PubMed ID: 18199555)

  • 1. Phosphatidylinositol ether lipid analogues induce AMP-activated protein kinase-dependent death in LKB1-mutant non small cell lung cancer cells.
    Memmott RM; Gills JJ; Hollingshead M; Powers MC; Chen Z; Kemp B; Kozikowski A; Dennis PA
    Cancer Res; 2008 Jan; 68(2):580-8. PubMed ID: 18199555
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Fibronectin stimulates non-small cell lung carcinoma cell growth through activation of Akt/mammalian target of rapamycin/S6 kinase and inactivation of LKB1/AMP-activated protein kinase signal pathways.
    Han S; Khuri FR; Roman J
    Cancer Res; 2006 Jan; 66(1):315-23. PubMed ID: 16397245
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Metformin enhances cisplatin cytotoxicity by suppressing signal transducer and activator of transcription-3 activity independently of the liver kinase B1-AMP-activated protein kinase pathway.
    Lin CC; Yeh HH; Huang WL; Yan JJ; Lai WW; Su WP; Chen HH; Su WC
    Am J Respir Cell Mol Biol; 2013 Aug; 49(2):241-50. PubMed ID: 23526220
    [TBL] [Abstract][Full Text] [Related]  

  • 4. eNOS activation mediated by AMPK after stimulation of endothelial cells with histamine or thrombin is dependent on LKB1.
    Thors B; Halldórsson H; Thorgeirsson G
    Biochim Biophys Acta; 2011 Feb; 1813(2):322-31. PubMed ID: 21145922
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The tumor suppressor gene TUSC2 (FUS1) sensitizes NSCLC to the AKT inhibitor MK2206 in LKB1-dependent manner.
    Meng J; Majidi M; Fang B; Ji L; Bekele BN; Minna JD; Roth JA
    PLoS One; 2013; 8(10):e77067. PubMed ID: 24146957
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Ca2+/calmodulin-dependent protein kinase kinase is involved in AMP-activated protein kinase activation by alpha-lipoic acid in C2C12 myotubes.
    Shen QW; Zhu MJ; Tong J; Ren J; Du M
    Am J Physiol Cell Physiol; 2007 Oct; 293(4):C1395-403. PubMed ID: 17687000
    [TBL] [Abstract][Full Text] [Related]  

  • 7. AMPK/TSC2/mTOR-signaling intermediates are not necessary for LKB1-mediated nuclear retention of PTEN tumor suppressor.
    Liu JL; Mao Z; Gallick GE; Yung WK
    Neuro Oncol; 2011 Feb; 13(2):184-94. PubMed ID: 21123367
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Dysfunctional AMPK activity, signalling through mTOR and survival in response to energetic stress in LKB1-deficient lung cancer.
    Carretero J; Medina PP; Blanco R; Smit L; Tang M; Roncador G; Maestre L; Conde E; Lopez-Rios F; Clevers HC; Sanchez-Cespedes M
    Oncogene; 2007 Mar; 26(11):1616-25. PubMed ID: 16953221
    [TBL] [Abstract][Full Text] [Related]  

  • 9. LKB1 gene inactivation does not sensitize non-small cell lung cancer cells to mTOR inhibitors in vitro.
    Xiao P; Sun LL; Wang J; Han RL; Ma Q; Zhong DS
    Acta Pharmacol Sin; 2015 Sep; 36(9):1107-12. PubMed ID: 26027660
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Calmodulin-dependent protein kinase kinase-beta is an alternative upstream kinase for AMP-activated protein kinase.
    Hawley SA; Pan DA; Mustard KJ; Ross L; Bain J; Edelman AM; Frenguelli BG; Hardie DG
    Cell Metab; 2005 Jul; 2(1):9-19. PubMed ID: 16054095
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Regulation of AMP-activated protein kinase by LKB1 and CaMKK in adipocytes.
    Gormand A; Henriksson E; Ström K; Jensen TE; Sakamoto K; Göransson O
    J Cell Biochem; 2011 May; 112(5):1364-75. PubMed ID: 21312243
    [TBL] [Abstract][Full Text] [Related]  

  • 12. A subset of VEGFR-TKIs activates AMPK in LKB1-mutant lung cancer.
    Yang L; Zhang Q; Xiong Y; Dang Z; Xiao H; Chen Q; Dai X; Zhang L; Zhu J; Wang D; Li M
    Cancer Sci; 2023 Apr; 114(4):1651-1662. PubMed ID: 36459496
    [TBL] [Abstract][Full Text] [Related]  

  • 13. AMP-activated protein kinase contributes to zinc-induced neuronal death via activation by LKB1 and induction of Bim in mouse cortical cultures.
    Eom JW; Lee JM; Koh JY; Kim YH
    Mol Brain; 2016 Feb; 9():14. PubMed ID: 26856538
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Concurrent regulation of LKB1 and CaMKK2 in the activation of AMPK in castrate-resistant prostate cancer by a well-defined polyherbal mixture with anticancer properties.
    MacDonald AF; Bettaieb A; Donohoe DR; Alani DS; Han A; Zhao Y; Whelan J
    BMC Complement Altern Med; 2018 Jun; 18(1):188. PubMed ID: 29914450
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The Effect of LKB1 Activity on the Sensitivity to PI3K/mTOR Inhibition in Non-Small Cell Lung Cancer.
    Shukuya T; Yamada T; Koenig MJ; Xu J; Okimoto T; Li F; Amann JM; Carbone DP
    J Thorac Oncol; 2019 Jun; 14(6):1061-1076. PubMed ID: 30825612
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Response of non-small cell lung cancer cells to the inhibitors of phosphatidylinositol 3-kinase/Akt- and MAPK kinase 4/c-Jun NH2-terminal kinase pathways: an effective therapeutic strategy for lung cancer.
    Lee HY; Oh SH; Suh YA; Baek JH; Papadimitrakopoulou V; Huang S; Hong WK
    Clin Cancer Res; 2005 Aug; 11(16):6065-74. PubMed ID: 16115952
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Aurora-A-mediated phosphorylation of LKB1 compromises LKB1/AMPK signaling axis to facilitate NSCLC growth and migration.
    Zheng X; Chi J; Zhi J; Zhang H; Yue D; Zhao J; Li D; Li Y; Gao M; Guo J
    Oncogene; 2018 Jan; 37(4):502-511. PubMed ID: 28967900
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Negative regulation of AMP-activated protein kinase (AMPK) activity by macrophage migration inhibitory factor (MIF) family members in non-small cell lung carcinomas.
    Brock SE; Rendon BE; Yaddanapudi K; Mitchell RA
    J Biol Chem; 2012 Nov; 287(45):37917-25. PubMed ID: 22988252
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Honokiol activates AMP-activated protein kinase in breast cancer cells via an LKB1-dependent pathway and inhibits breast carcinogenesis.
    Nagalingam A; Arbiser JL; Bonner MY; Saxena NK; Sharma D
    Breast Cancer Res; 2012 Feb; 14(1):R35. PubMed ID: 22353783
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Carnosic Acid against Lung Cancer: Induction of Autophagy and Activation of Sestrin-2/LKB1/AMPK Signalling.
    O'Neill EJ; Sze NSK; MacPherson REK; Tsiani E
    Int J Mol Sci; 2024 Feb; 25(4):. PubMed ID: 38396629
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 33.