138 related articles for article (PubMed ID: 18201749)
1. Tyr178 of beta3 is critical for alphaIIb maturation and macromolecular ligand binding to alphaIIbbeta3.
Sun CX; Chen P; Lu W; Liu JN
Thromb Res; 2008; 122(2):203-10. PubMed ID: 18201749
[TBL] [Abstract][Full Text] [Related]
2. A naturally occurring point mutation in the beta3 integrin MIDAS-like domain affects differently alphavbeta3 and alphaIIIbbeta3 receptor function.
Morel-Kopp MC; Melchior C; Chen P; Ammerlaan W; Lecompte T; Kaplan C; Kieffer N
Thromb Haemost; 2001 Dec; 86(6):1425-34. PubMed ID: 11776310
[TBL] [Abstract][Full Text] [Related]
3. A two-amino acid insertion in the Cys146- Cys167 loop of the alphaIIb subunit is associated with a variant of Glanzmann thrombasthenia. Critical role of Asp163 in ligand binding.
Honda S; Tomiyama Y; Shiraga M; Tadokoro S; Takamatsu J; Saito H; Kurata Y; Matsuzawa Y
J Clin Invest; 1998 Sep; 102(6):1183-92. PubMed ID: 9739052
[TBL] [Abstract][Full Text] [Related]
4. Identification of critical residues for ligand binding in the integrin beta3 I-domain by site-directed mutagenesis.
Yamanouchi J; Hato T; Tamura T; Fujita S
Thromb Haemost; 2002 Apr; 87(4):756-62. PubMed ID: 12008962
[TBL] [Abstract][Full Text] [Related]
5. AlphaIIbG236E causes Glanzmann thrombasthenia by impairing association with beta3.
Afrasiabi A; Gelain F; Artoni A; Mannucci PM
Platelets; 2008 Aug; 19(5):322-7. PubMed ID: 18791937
[TBL] [Abstract][Full Text] [Related]
6. Critical residues for ligand binding in blade 2 of the propeller domain of the integrin alphaIIb subunit.
Tamura T; Hato T; Yamanouchi J; Fujita S
Thromb Haemost; 2004 Jan; 91(1):111-8. PubMed ID: 14691576
[TBL] [Abstract][Full Text] [Related]
7. A novel Pro126His beta propeller mutation in integrin alphaIIb causes Glanzmann thrombasthenia by impairing progression of pro-alphaIIbbeta3 from endoplasmic reticulum to Golgi.
Shen WZ; Ding QL; Jin PP; Wang XF; Jiang YZ; Li SM; Wang HL
Blood Cells Mol Dis; 2009; 42(1):44-50. PubMed ID: 18976939
[TBL] [Abstract][Full Text] [Related]
8. Regulation of integrin αIIbβ3 ligand binding and signaling by the metal ion binding sites in the β I domain.
Raborn J; Wang W; Luo BH
Biochemistry; 2011 Mar; 50(12):2084-91. PubMed ID: 21309594
[TBL] [Abstract][Full Text] [Related]
9. A beta3 Asp217-->Val substitution in a patient with variant Glanzmann Thrombasthenia severely affects integrin alphaIIBbeta3 functions.
D'Andrea G; Bafunno V; Del Vecchio L; Amoriello A; Morabito P; Vecchione G; Grandone E; Margaglione M
Blood Coagul Fibrinolysis; 2008 Oct; 19(7):657-62. PubMed ID: 18832906
[TBL] [Abstract][Full Text] [Related]
10. Construction of drug screening cell model and application to new compounds inhibiting FITC-fibrinogen binding to CHO cells expressing human alphaIIbbeta3.
Yang J; Yao J; Chen J; Wang XN; Zhu TY; Chen LL; Chu P
Eur J Pharmacol; 2009 Sep; 618(1-3):1-8. PubMed ID: 19619528
[TBL] [Abstract][Full Text] [Related]
11. Fibrinogen interaction of CHO cells expressing chimeric alphaIIb/alphavbeta3 integrin.
Chen JJ; Su XY; Xi XD; Lin LP; Ding J; Lu H
Acta Pharmacol Sin; 2008 Feb; 29(2):204-10. PubMed ID: 18215349
[TBL] [Abstract][Full Text] [Related]
12. Allicin and disulfiram enhance platelet integrin alphaIIbbeta3-fibrinogen binding.
Manaster Y; Shenkman B; Rosenberg N; Savion N
Thromb Res; 2009 Sep; 124(4):477-82. PubMed ID: 19632706
[TBL] [Abstract][Full Text] [Related]
13. A mechanistic model for paradoxical platelet activation by ligand-mimetic alphaIIb beta3 (GPIIb/IIIa) antagonists.
Bassler N; Loeffler C; Mangin P; Yuan Y; Schwarz M; Hagemeyer CE; Eisenhardt SU; Ahrens I; Bode C; Jackson SP; Peter K
Arterioscler Thromb Vasc Biol; 2007 Mar; 27(3):e9-15. PubMed ID: 17170374
[TBL] [Abstract][Full Text] [Related]
14. A variant thrombasthenic phenotype associated with compound heterozygosity of integrin beta3-subunit: (Met124Val)beta3 alters the subunit dimerization rendering a decreased number of constitutive active alphaIIbbeta3 receptors.
González-Manchón C; Butta N; Larrucea S; Arias-Salgado EG; Alonso S; López A; Parrilla R
Thromb Haemost; 2004 Dec; 92(6):1377-86. PubMed ID: 15583747
[TBL] [Abstract][Full Text] [Related]
15. A naturally occurring mutation near the amino terminus of alphaIIb defines a new region involved in ligand binding to alphaIIbbeta3.
Basani RB; French DL; Vilaire G; Brown DL; Chen F; Coller BS; Derrick JM; Gartner TK; Bennett JS; Poncz M
Blood; 2000 Jan; 95(1):180-8. PubMed ID: 10607701
[TBL] [Abstract][Full Text] [Related]
16. The disintegrin echistatin stabilizes integrin alphaIIbbeta3's open conformation and promotes its oligomerization.
Hantgan RR; Stahle MC; Connor JH; Lyles DS; Horita DA; Rocco M; Nagaswami C; Weisel JW; McLane MA
J Mol Biol; 2004 Oct; 342(5):1625-36. PubMed ID: 15364586
[TBL] [Abstract][Full Text] [Related]
17. The novel S527F mutation in the integrin beta3 chain induces a high affinity alphaIIbbeta3 receptor by hindering adoption of the bent conformation.
Vanhoorelbeke K; De Meyer SF; Pareyn I; Melchior C; Plançon S; Margue C; Pradier O; Fondu P; Kieffer N; Springer TA; Deckmyn H
J Biol Chem; 2009 May; 284(22):14914-20. PubMed ID: 19329429
[TBL] [Abstract][Full Text] [Related]
18. Suppression of integrin activation by the membrane-distal sequence of the integrin alphaIIb cytoplasmic tail.
Yamanouchi J; Hato T; Tamura T; Fujita S
Biochem J; 2004 Apr; 379(Pt 2):317-23. PubMed ID: 14723599
[TBL] [Abstract][Full Text] [Related]
19. β-Subunit Binding Is Sufficient for Ligands to Open the Integrin αIIbβ3 Headpiece.
Lin FY; Zhu J; Eng ET; Hudson NE; Springer TA
J Biol Chem; 2016 Feb; 291(9):4537-46. PubMed ID: 26631735
[TBL] [Abstract][Full Text] [Related]
20. Probing conformational changes in the I-like domain and the cysteine-rich repeat of human beta 3 integrins following disulfide bond disruption by cysteine mutations: identification of cysteine 598 involved in alphaIIbbeta3 activation.
Chen P; Melchior C; Brons NH; Schlegel N; Caen J; Kieffer N
J Biol Chem; 2001 Oct; 276(42):38628-35. PubMed ID: 11507099
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]