BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

215 related articles for article (PubMed ID: 18205116)

  • 1. Synthesis and stability in biological media of 1H-imidazole-1-carboxylates of ROS203, an antagonist of the histamine H3 receptor.
    Rivara M; Vacondio F; Silva C; Zuliani V; Fantini M; Bordi F; Plazzi PV; Bertoni S; Ballabeni V; Flammini L; Barocelli E; Mor M
    Chem Biodivers; 2008 Jan; 5(1):140-52. PubMed ID: 18205116
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Synthesis and in vitro pharmacology of a series of new chiral histamine H3-receptor ligands: 2-(R and S)-Amino-3-(1H-imidazol-4(5)-yl)propyl ether derivatives.
    Kovalainen JT; Christiaans JA; Kotisaari S; Laitinen JT; Männistö PT; Tuomisto L; Gynther J
    J Med Chem; 1999 Apr; 42(7):1193-202. PubMed ID: 10197963
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Development of chiral N-alkylcarbamates as new leads for potent and selective H3-receptor antagonists: synthesis, capillary electrophoresis, and in vitro and oral in vivo activity.
    Sasse A; Kiec-Kononowicz K; Stark H; Motyl M; Reidemeister S; Ganellin CR; Ligneau X; Schwartz JC; Schunack W
    J Med Chem; 1999 Feb; 42(4):593-600. PubMed ID: 10052966
    [TBL] [Abstract][Full Text] [Related]  

  • 4. 4-(omega-(alkyloxy)alkyl)-1H-imidazole derivatives as histamine H(3) receptor antagonists/agonists.
    Meier G; Krause M; Hüls A; Ligneau X; Pertz HH; Arrang JM; Ganellin CR; Schwartz JC; Schunack W; Stark H
    J Med Chem; 2004 May; 47(10):2678-87. PubMed ID: 15115409
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Imidazole H3-antagonists: relationship between structure and ex vivo binding to rat brain H3-receptors.
    Vacondio F; Mor M; Silva C; Zuliani V; Rivara M; Rivara S; Bordi F; Plazzi PV; Magnanini F; Bertoni S; Ballabeni V; Barocelli E; Carrupt PA; Testa B
    Eur J Pharm Sci; 2004 Sep; 23(1):89-98. PubMed ID: 15324926
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Novel carbamates as potent histamine H3 receptor antagonists with high in vitro and oral in vivo activity.
    Stark H; Purand K; Ligneau X; Rouleau A; Arrang JM; Garbarg M; Schwartz JC; Schunack W
    J Med Chem; 1996 Mar; 39(5):1157-63. PubMed ID: 8676353
    [TBL] [Abstract][Full Text] [Related]  

  • 7. A novel series of (phenoxyalkyl)imidazoles as potent H3-receptor histamine antagonists.
    Ganellin CR; Fkyerat A; Bang-Andersen B; Athmani S; Tertiuk W; Garbarg M; Ligneau X; Schwartz JC
    J Med Chem; 1996 Sep; 39(19):3806-13. PubMed ID: 8809168
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Meta-substituted aryl(thio)ethers as potent partial agonists (or antagonists) for the histamine H3 receptor lacking a nitrogen atom in the side chain.
    Pelloux-Léon N; Fkyerat A; Piripitsi A; Tertiuk W; Schunack W; Stark H; Garbarg M; Ligneau X; Arrang JM; Schwartz JC; Ganellin CR
    J Med Chem; 2004 Jun; 47(12):3264-74. PubMed ID: 15163206
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Histamine H3 and H4 receptor affinity of branched 3-(1H-imidazol-4-yl)propyl N-alkylcarbamates.
    Łazewska D; Wiecek M; Ligneau X; Kottke T; Weizel L; Seifert R; Schunack W; Stark H; Kieć-Kononowicz K
    Bioorg Med Chem Lett; 2009 Dec; 19(23):6682-5. PubMed ID: 19846299
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Novel imidazole-based histamine H3 antagonists.
    Jablonowski JA; Ly KS; Bogenstaetter M; Dvorak CA; Boggs JD; Dvorak LK; Lord B; Miller KL; Mazur C; Wilson SJ; Lovenberg TW; Carruthers NI
    Bioorg Med Chem Lett; 2009 Feb; 19(3):903-7. PubMed ID: 19119007
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Novel histamine H3 receptor antagonists based on the 4-[(1H-imidazol-4-yl)methyl]piperidine scaffold.
    Vaccaro WD; Sher R; Berlin M; Shih NY; Aslanian R; Schwerdt JH; McCormick KD; Piwinski JJ; West RE; Anthes JC; Williams SM; Wu RL; She HS; Rivelli MA; Mutter JC; Corboz MR; Hey JA; Favreau L
    Bioorg Med Chem Lett; 2006 Jan; 16(2):395-9. PubMed ID: 16246552
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Stereochemical diversity-oriented conformational restriction strategy. Development of potent histamine H3 and/or H4 receptor antagonists with an imidazolylcyclopropane structure.
    Watanabe M; Kazuta Y; Hayashi H; Yamada S; Matsuda A; Shuto S
    J Med Chem; 2006 Sep; 49(18):5587-96. PubMed ID: 16942032
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Clobenpropit analogs as dual activity ligands for the histamine H3 and H4 receptors: synthesis, pharmacological evaluation, and cross-target QSAR studies.
    Lim HD; Istyastono EP; van de Stolpe A; Romeo G; Gobbi S; Schepers M; Lahaye R; Menge WM; Zuiderveld OP; Jongejan A; Smits RA; Bakker RA; Haaksma EE; Leurs R; de Esch IJ
    Bioorg Med Chem; 2009 Jun; 17(11):3987-94. PubMed ID: 19414267
    [TBL] [Abstract][Full Text] [Related]  

  • 14. N(alpha)-imidazolylalkyl and pyridylalkyl derivatives of histaprodifen: synthesis and in vitro evaluation of highly potent histamine H(1)-receptor agonists.
    Menghin S; Pertz HH; Kramer K; Seifert R; Schunack W; Elz S
    J Med Chem; 2003 Dec; 46(25):5458-70. PubMed ID: 14640554
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Validation of a histamine H3 receptor model through structure-activity relationships for classical H3 antagonists.
    Lorenzi S; Mor M; Bordi F; Rivara S; Rivara M; Morini G; Bertoni S; Ballabeni V; Barocelli E; Plazzi PV
    Bioorg Med Chem; 2005 Oct; 13(19):5647-57. PubMed ID: 16085419
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Diamine derivatives containing imidazolidinylidene propanedinitrile as a new class of histamine H3 receptor antagonists. Part I.
    Sasho S; Seishi T; Kawamura M; Hirose R; Toki S; Shimada JI
    Bioorg Med Chem Lett; 2008 Apr; 18(7):2288-91. PubMed ID: 18353639
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Fluorinated non-imidazole histamine H3 receptor antagonists.
    Isensee K; Amon M; Garlapati A; Ligneau X; Camelin JC; Capet M; Schwartz JC; Stark H
    Bioorg Med Chem Lett; 2009 Apr; 19(8):2172-5. PubMed ID: 19286376
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Synthesis and preliminary pharmacological investigation of new N-substituted-N-[ω-(ω-phenoxy-alkylpiperazin-1-yl)alkyl]guanidines as non-imidazole histamine H(3) antagonists.
    Staszewski M; Walczyński K
    Arch Pharm (Weinheim); 2012 Jun; 345(6):431-43. PubMed ID: 22415744
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Synthesis, biological activity, QSAR and QSPR study of 2-aminobenzimidazole derivatives as potent H3-antagonists.
    Mor M; Bordi F; Silva C; Rivara S; Zuliani V; Vacondio F; Rivara M; Barocelli E; Bertoni S; Ballabeni V; Magnanini F; Impicciatore M; Plazzi PV
    Bioorg Med Chem; 2004 Feb; 12(4):663-74. PubMed ID: 14759727
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Discovery of a new class of non-imidazole oxazoline-based histamine H(3) receptor (H(3)R) inverse agonists.
    Célanire S; Wijtmans M; Christophe B; Collart P; de Esch I; Dassesse D; Delaunoy C; Denonne F; Durieu V; Gelens E; Gillard M; Lallemand B; Lamberty Y; Lebon F; Nicolas JM; Quéré L; Snip E; Vanbellinghen A; Van Houtvin N; Verbois V; Timmerman H; Talaga P; Leurs R; Provins L
    ChemMedChem; 2009 Jul; 4(7):1063-8. PubMed ID: 19405064
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.