232 related articles for article (PubMed ID: 18206986)
1. Novel functions of the alpha-ketoglutarate dehydrogenase complex may mediate diverse oxidant-induced changes in mitochondrial enzymes associated with Alzheimer's disease.
Shi Q; Xu H; Kleinman WA; Gibson GE
Biochim Biophys Acta; 2008 Apr; 1782(4):229-38. PubMed ID: 18206986
[TBL] [Abstract][Full Text] [Related]
2. Reduction in the E2k subunit of the alpha-ketoglutarate dehydrogenase complex has effects independent of complex activity.
Shi Q; Chen HL; Xu H; Gibson GE
J Biol Chem; 2005 Mar; 280(12):10888-96. PubMed ID: 15649899
[TBL] [Abstract][Full Text] [Related]
3. Inactivation and reactivation of the mitochondrial α-ketoglutarate dehydrogenase complex.
Shi Q; Xu H; Yu H; Zhang N; Ye Y; Estevez AG; Deng H; Gibson GE
J Biol Chem; 2011 May; 286(20):17640-8. PubMed ID: 21454586
[TBL] [Abstract][Full Text] [Related]
4. Oxidative stress increases internal calcium stores and reduces a key mitochondrial enzyme.
Gibson GE; Zhang H; Xu H; Park LC; Jeitner TM
Biochim Biophys Acta; 2002 Mar; 1586(2):177-89. PubMed ID: 11959459
[TBL] [Abstract][Full Text] [Related]
5. Abnormality of the alpha-ketoglutarate dehydrogenase complex in fibroblasts from familial Alzheimer's disease.
Sheu KF; Cooper AJ; Koike K; Koike M; Lindsay JG; Blass JP
Ann Neurol; 1994 Mar; 35(3):312-8. PubMed ID: 8122883
[TBL] [Abstract][Full Text] [Related]
6. Reductions in the mitochondrial enzyme α-ketoglutarate dehydrogenase complex in neurodegenerative disease - beneficial or detrimental?
Chen H; Denton TT; Xu H; Calingasan N; Beal MF; Gibson GE
J Neurochem; 2016 Dec; 139(5):823-838. PubMed ID: 27580471
[TBL] [Abstract][Full Text] [Related]
7. Responses of the mitochondrial alpha-ketoglutarate dehydrogenase complex to thiamine deficiency may contribute to regional selective vulnerability.
Shi Q; Karuppagounder SS; Xu H; Pechman D; Chen H; Gibson GE
Neurochem Int; 2007 Jun; 50(7-8):921-31. PubMed ID: 17482317
[TBL] [Abstract][Full Text] [Related]
8. Mitochondrial enzymes and endoplasmic reticulum calcium stores as targets of oxidative stress in neurodegenerative diseases.
Gibson GE; Huang HM
J Bioenerg Biomembr; 2004 Aug; 36(4):335-40. PubMed ID: 15377868
[TBL] [Abstract][Full Text] [Related]
9. Alpha-ketoglutarate dehydrogenase complex-dependent succinylation of proteins in neurons and neuronal cell lines.
Gibson GE; Xu H; Chen HL; Chen W; Denton TT; Zhang S
J Neurochem; 2015 Jul; 134(1):86-96. PubMed ID: 25772995
[TBL] [Abstract][Full Text] [Related]
10. Deficits in the mitochondrial enzyme α-ketoglutarate dehydrogenase lead to Alzheimer's disease-like calcium dysregulation.
Gibson GE; Chen HL; Xu H; Qiu L; Xu Z; Denton TT; Shi Q
Neurobiol Aging; 2012 Jun; 33(6):1121.e13-24. PubMed ID: 22169199
[TBL] [Abstract][Full Text] [Related]
11. The alpha-ketoglutarate-dehydrogenase complex: a mediator between mitochondria and oxidative stress in neurodegeneration.
Gibson GE; Blass JP; Beal MF; Bunik V
Mol Neurobiol; 2005; 31(1-3):43-63. PubMed ID: 15953811
[TBL] [Abstract][Full Text] [Related]
12. Alpha-ketoglutarate dehydrogenase in Alzheimer brains bearing the APP670/671 mutation.
Gibson GE; Zhang H; Sheu KF; Bogdanovich N; Lindsay JG; Lannfelt L; Vestling M; Cowburn RF
Ann Neurol; 1998 Oct; 44(4):676-81. PubMed ID: 9778267
[TBL] [Abstract][Full Text] [Related]
13. alpha-Ketoglutarate dehydrogenase contributes to production of reactive oxygen species in glutamate-stimulated hippocampal neurons in situ.
Zündorf G; Kahlert S; Bunik VI; Reiser G
Neuroscience; 2009 Jan; 158(2):610-6. PubMed ID: 18996448
[TBL] [Abstract][Full Text] [Related]
14. Mitochondrial alpha-ketoglutarate dehydrogenase complex generates reactive oxygen species.
Starkov AA; Fiskum G; Chinopoulos C; Lorenzo BJ; Browne SE; Patel MS; Beal MF
J Neurosci; 2004 Sep; 24(36):7779-88. PubMed ID: 15356189
[TBL] [Abstract][Full Text] [Related]
15. Inhibition of Krebs cycle enzymes by hydrogen peroxide: A key role of [alpha]-ketoglutarate dehydrogenase in limiting NADH production under oxidative stress.
Tretter L; Adam-Vizi V
J Neurosci; 2000 Dec; 20(24):8972-9. PubMed ID: 11124972
[TBL] [Abstract][Full Text] [Related]
16. Oxidative stress and a key metabolic enzyme in Alzheimer brains, cultured cells, and an animal model of chronic oxidative deficits.
Gibson GE; Park LC; Zhang H; Sorbi S; Calingasan NY
Ann N Y Acad Sci; 1999; 893():79-94. PubMed ID: 10672231
[TBL] [Abstract][Full Text] [Related]
17. Reverse and Forward Electron Flow-Induced H
Horváth G; Sváb G; Komlódi T; Ravasz D; Kacsó G; Doczi J; Chinopoulos C; Ambrus A; Tretter L
Antioxidants (Basel); 2022 Jul; 11(8):. PubMed ID: 36009207
[TBL] [Abstract][Full Text] [Related]
18. Mild mitochondrial metabolic deficits by α-ketoglutarate dehydrogenase inhibition cause prominent changes in intracellular autophagic signaling: Potential role in the pathobiology of Alzheimer's disease.
Banerjee K; Munshi S; Xu H; Frank DE; Chen HL; Chu CT; Yang J; Cho S; Kagan VE; Denton TT; Tyurina YY; Jiang JF; Gibson GE
Neurochem Int; 2016 Jun; 96():32-45. PubMed ID: 26923918
[TBL] [Abstract][Full Text] [Related]
19. Inhibition of the alpha-ketoglutarate dehydrogenase complex alters mitochondrial function and cellular calcium regulation.
Huang HM; Zhang H; Xu H; Gibson GE
Biochim Biophys Acta; 2003 Jan; 1637(1):119-26. PubMed ID: 12527416
[TBL] [Abstract][Full Text] [Related]
20. Examination of the superoxide/hydrogen peroxide forming and quenching potential of mouse liver mitochondria.
Slade L; Chalker J; Kuksal N; Young A; Gardiner D; Mailloux RJ
Biochim Biophys Acta Gen Subj; 2017 Aug; 1861(8):1960-1969. PubMed ID: 28506882
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
