116 related articles for article (PubMed ID: 18207300)
1. Aldo-keto reductase 1C2 is essential for 1-nitropyrene's but not for benzo[a]pyrene's induction of p53 phosphorylation and apoptosis.
Su JG; Liao PJ; Huang MC; Chu WC; Lin SC; Chang YJ
Toxicology; 2008 Feb; 244(2-3):257-70. PubMed ID: 18207300
[TBL] [Abstract][Full Text] [Related]
2. Effects of nitrated-polycyclic aromatic hydrocarbons and diesel exhaust particle extracts on cell signalling related to apoptosis: possible implications for their mutagenic and carcinogenic effects.
Landvik NE; Gorria M; Arlt VM; Asare N; Solhaug A; Lagadic-Gossmann D; Holme JA
Toxicology; 2007 Mar; 231(2-3):159-74. PubMed ID: 17240030
[TBL] [Abstract][Full Text] [Related]
3. Isoform-specific induction of a human aldo-keto reductase by polycyclic aromatic hydrocarbons (PAHs), electrophiles, and oxidative stress: implications for the alternative pathway of PAH activation catalyzed by human dihydrodiol dehydrogenase.
Burczynski ME; Lin HK; Penning TM
Cancer Res; 1999 Feb; 59(3):607-14. PubMed ID: 9973208
[TBL] [Abstract][Full Text] [Related]
4. Role of cell signalling involved in induction of apoptosis by benzo[a]pyrene and cyclopenta[c,d]pyrene in Hepa1c1c7 cells.
Solhaug A; Refsnes M; Holme JA
J Cell Biochem; 2004 Dec; 93(6):1143-54. PubMed ID: 15449320
[TBL] [Abstract][Full Text] [Related]
5. Genotoxic polycyclic aromatic hydrocarbon ortho-quinones generated by aldo-keto reductases induce CYP1A1 via nuclear translocation of the aryl hydrocarbon receptor.
Burczynski ME; Penning TM
Cancer Res; 2000 Feb; 60(4):908-15. PubMed ID: 10706104
[TBL] [Abstract][Full Text] [Related]
6. Genotoxic effects of 1-nitropyrene in macrophages are mediated through a p53-dependent pathway involving cytochrome c release, caspase activation, and PARP-1 cleavage.
Wu SW; Su CH; Ho YC; Huang-Liu R; Tseng CC; Chiang YW; Yeh KL; Lee SS; Chen WY; Chen CJ; Li YC; Lee CY; Kuan YH
Ecotoxicol Environ Saf; 2021 Apr; 213():112062. PubMed ID: 33618169
[TBL] [Abstract][Full Text] [Related]
7. Role of cell signaling in B[a]P-induced apoptosis: characterization of unspecific effects of cell signaling inhibitors and apoptotic effects of B[a]P metabolites.
Solhaug A; Øvrebø S; Mollerup S; Låg M; Schwarze PE; Nesnow S; Holme JA
Chem Biol Interact; 2005 Jan; 151(2):101-19. PubMed ID: 15698582
[TBL] [Abstract][Full Text] [Related]
8. DNA damage and DNA damage response in human bronchial epithelial BEAS-2B cells following exposure to 2-nitrobenzanthrone and 3-nitrobenzanthrone: role in apoptosis.
Oya E; Ovrevik J; Arlt VM; Nagy E; Phillips DH; Holme JA
Mutagenesis; 2011 Nov; 26(6):697-708. PubMed ID: 21715570
[TBL] [Abstract][Full Text] [Related]
9. Aldo-keto reductases protect lung adenocarcinoma cells from the acute toxicity of B[a]P-7,8-trans-dihydrodiol.
Abedin Z; Sen S; Field J
Chem Res Toxicol; 2012 Jan; 25(1):113-21. PubMed ID: 22053912
[TBL] [Abstract][Full Text] [Related]
10. 1-Nitropyrene stabilizes the mRNA of cytochrome P450 1a1, a carcinogen-metabolizing enzyme, via the Akt pathway.
Chu WC; Hong WF; Huang MC; Chen FY; Lin SC; Liao PJ; Su JG
Chem Res Toxicol; 2009 Dec; 22(12):1938-47. PubMed ID: 19961161
[TBL] [Abstract][Full Text] [Related]
11. Reactive oxygen species generated by PAH o-quinones cause change-in-function mutations in p53.
Yu D; Berlin JA; Penning TM; Field J
Chem Res Toxicol; 2002 Jun; 15(6):832-42. PubMed ID: 12067251
[TBL] [Abstract][Full Text] [Related]
12. Polycyclic aromatic hydrocarbon carcinogens increase ubiquitination of p21 protein after the stabilization of p53 and the expression of p21.
Nakanishi Y; Pei XH; Takayama K; Bai F; Izumi M; Kimotsuki K; Inoue K; Minami T; Wataya H; Hara N
Am J Respir Cell Mol Biol; 2000 Jun; 22(6):747-54. PubMed ID: 10837373
[TBL] [Abstract][Full Text] [Related]
13. Polycyclic aromatic hydrocarbons induce both apoptotic and anti-apoptotic signals in Hepa1c1c7 cells.
Solhaug A; Refsnes M; Låg M; Schwarze PE; Husøy T; Holme JA
Carcinogenesis; 2004 May; 25(5):809-19. PubMed ID: 14729587
[TBL] [Abstract][Full Text] [Related]
14. Competing roles of cytochrome P450 1A1/1B1 and aldo-keto reductase 1A1 in the metabolic activation of (+/-)-7,8-dihydroxy-7,8-dihydro-benzo[a]pyrene in human bronchoalveolar cell extracts.
Jiang H; Shen YM; Quinn AM; Penning TM
Chem Res Toxicol; 2005 Feb; 18(2):365-74. PubMed ID: 15720144
[TBL] [Abstract][Full Text] [Related]
15. Toxic effects of methylated benzo[a]pyrenes in rat liver stem-like cells.
Trilecová L; Krčková S; Marvanová S; Pĕnčíková K; Krčmář P; Neča J; Hulinková P; Pálková L; Ciganek M; Milcová A; Topinka J; Vondráček J; Machala M
Chem Res Toxicol; 2011 Jun; 24(6):866-76. PubMed ID: 21604763
[TBL] [Abstract][Full Text] [Related]
16. Suppressive effect of 1-nitropyrene on benzo[a]pyrene-induced CYP1A1 protein expression in HepG2 cells.
Cherng SH; Hsu SL; Yang JL; Yu CT; Lee H
Toxicol Lett; 2006 Mar; 161(3):236-43. PubMed ID: 16280210
[TBL] [Abstract][Full Text] [Related]
17. Abundance of aryl hydrocarbon receptor potentiates benzo[a]pyrene-induced apoptosis in Hepa1c1c7 cells via CYP1A1 activation.
Chung JY; Kim JY; Kim WR; Lee SG; Kim YJ; Park JE; Hong YP; Chun YJ; Park YC; Oh S; Yoo KS; Yoo YH; Kim JM
Toxicology; 2007 Jun; 235(1-2):62-72. PubMed ID: 17433523
[TBL] [Abstract][Full Text] [Related]
18. Human aldo-keto reductases and the metabolic activation of polycyclic aromatic hydrocarbons.
Penning TM
Chem Res Toxicol; 2014 Nov; 27(11):1901-17. PubMed ID: 25279998
[TBL] [Abstract][Full Text] [Related]
19. Mechanisms involved in lipid accumulation and apoptosis induced by 1-nitropyrene in Hepa1c1c7 cells.
Podechard N; Tekpli X; Catheline D; Holme JA; Rioux V; Legrand P; Rialland M; Fardel O; Lagadic-Gossmann D; Lecureur V
Toxicol Lett; 2011 Oct; 206(3):289-99. PubMed ID: 21872649
[TBL] [Abstract][Full Text] [Related]
20. Activation of polycyclic aromatic hydrocarbon trans-dihydrodiol proximate carcinogens by human aldo-keto reductase (AKR1C) enzymes and their functional overexpression in human lung carcinoma (A549) cells.
Palackal NT; Lee SH; Harvey RG; Blair IA; Penning TM
J Biol Chem; 2002 Jul; 277(27):24799-808. PubMed ID: 11978787
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]