These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

137 related articles for article (PubMed ID: 18215359)

  • 1. Discovery of a novel competitive inhibitor of PTP1B by high-throughput screening.
    Shi L; Yu HP; Zhou YY; Du JQ; Shen Q; Li JY; Li J
    Acta Pharmacol Sin; 2008 Feb; 29(2):278-84. PubMed ID: 18215359
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Discovery of novel, high potent, ABC type PTP1B inhibitors with TCPTP selectivity and cellular activity.
    Liu P; Du Y; Song L; Shen J; Li Q
    Eur J Med Chem; 2016 Aug; 118():27-33. PubMed ID: 27123900
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Synthesis and characterization of 5,7-dihydroxyflavanone derivatives as novel protein tyrosine phosphatase 1B inhibitors.
    Sun LP; Ma WP; Gao LX; Yang LL; Quan YC; Li J; Piao HR
    J Enzyme Inhib Med Chem; 2013 Dec; 28(6):1199-204. PubMed ID: 23009604
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Oleanolic acid and its derivatives: new inhibitor of protein tyrosine phosphatase 1B with cellular activities.
    Zhang YN; Zhang W; Hong D; Shi L; Shen Q; Li JY; Li J; Hu LH
    Bioorg Med Chem; 2008 Sep; 16(18):8697-705. PubMed ID: 18707891
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Synthesis and biological evaluation of novel bis-aromatic amides as novel PTP1B inhibitors.
    Wang WL; Huang C; Gao LX; Tang CL; Wang JQ; Wu MC; Sheng L; Chen HJ; Nan FJ; Li JY; Li J; Feng B
    Bioorg Med Chem Lett; 2014 Apr; 24(8):1889-94. PubMed ID: 24684845
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Virtual Screening of Novel and Selective Inhibitors of Protein Tyrosine Phosphatase 1B over T-Cell Protein Tyrosine Phosphatase Using a Bidentate Inhibition Strategy.
    Chen X; Gan Q; Feng C; Liu X; Zhang Q
    J Chem Inf Model; 2018 Apr; 58(4):837-847. PubMed ID: 29608303
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Novel thiophene derivatives as PTP1B inhibitors with selectivity and cellular activity.
    Ye D; Zhang Y; Wang F; Zheng M; Zhang X; Luo X; Shen X; Jiang H; Liu H
    Bioorg Med Chem; 2010 Mar; 18(5):1773-82. PubMed ID: 20153651
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The discovery of a novel and selective inhibitor of PTP1B over TCPTP: 3D QSAR pharmacophore modeling, virtual screening, synthesis, and biological evaluation.
    Ma Y; Jin YY; Wang YL; Wang RL; Lu XH; Kong DX; Xu WR
    Chem Biol Drug Des; 2014 Jun; 83(6):697-709. PubMed ID: 24418013
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Design, synthesis and biological evaluation of uncharged catechol derivatives as selective inhibitors of PTP1B.
    Li XQ; Xu Q; Luo J; Wang LJ; Jiang B; Zhang RS; Shi DY
    Eur J Med Chem; 2017 Aug; 136():348-359. PubMed ID: 28511130
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Novel, potent, selective and cellular active ABC type PTP1B inhibitors containing (methanesulfonyl-phenyl-amino)-acetic acid methyl ester phosphotyrosine mimetic.
    Liu P; Du Y; Song L; Shen J; Li Q
    Bioorg Med Chem; 2015 Nov; 23(21):7079-88. PubMed ID: 26481657
    [TBL] [Abstract][Full Text] [Related]  

  • 11. 4-Quinolone-3-carboxylic acids as cell-permeable inhibitors of protein tyrosine phosphatase 1B.
    Zhi Y; Gao LX; Jin Y; Tang CL; Li JY; Li J; Long YQ
    Bioorg Med Chem; 2014 Jul; 22(14):3670-83. PubMed ID: 24906513
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Discovery and evaluation of the hybrid of bromophenol and saccharide as potent and selective protein tyrosine phosphatase 1B inhibitors.
    Zhang R; Yu R; Xu Q; Li X; Luo J; Jiang B; Wang L; Guo S; Wu N; Shi D
    Eur J Med Chem; 2017 Jul; 134():24-33. PubMed ID: 28395151
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Design, synthesis, and biological evaluation of novel 2-ethyl-5-phenylthiazole-4-carboxamide derivatives as protein tyrosine phosphatase 1B inhibitors with improved cellular efficacy.
    Chen YT; Tang CL; Ma WP; Gao LX; Wei Y; Zhang W; Li JY; Li J; Nan FJ
    Eur J Med Chem; 2013 Nov; 69():399-412. PubMed ID: 24090912
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Design, synthesis and insulin-sensitising effects of novel PTP1B inhibitors.
    Tang YB; Lu D; Chen Z; Hu C; Yang Y; Tian JY; Ye F; Wu L; Zhang ZY; Xiao Z
    Bioorg Med Chem Lett; 2013 Apr; 23(8):2313-8. PubMed ID: 23499238
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Identification of protein tyrosine phosphatase 1B (PTP1B) inhibitors through De Novo Evoluton, synthesis, biological evaluation and molecular dynamics simulation.
    Wu J; Ma Y; Zhou H; Zhou L; Du S; Sun Y; Li W; Dong W; Wang R
    Biochem Biophys Res Commun; 2020 May; 526(1):273-280. PubMed ID: 32209254
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Discovery of novel high potent and cellular active ADC type PTP1B inhibitors with selectivity over TC-PTP via modification interacting with C site.
    Du Y; Zhang Y; Ling H; Li Q; Shen J
    Eur J Med Chem; 2018 Jan; 144():692-700. PubMed ID: 29289892
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Combined Ligand- and Receptor-Based Virtual Screening Methodology to Identify Structurally Diverse Protein Tyrosine Phosphatase 1B Inhibitors.
    Gimeno A; Ardid-Ruiz A; Ojeda-Montes MJ; Tomás-Hernández S; Cereto-Massagué A; Beltrán-Debón R; Mulero M; Valls C; Aragonès G; Suárez M; Pujadas G; Garcia-Vallvé S
    ChemMedChem; 2018 Sep; 13(18):1939-1948. PubMed ID: 30024103
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Diphenylether derivative as selective inhibitor of protein tyrosine phosphatase 1B (PTP1B) over t-cell protein tyrosine phosphatase (TCPTP) identified through virtual screening.
    Reddy MV; Ghadiyaram C; Panigrahi SK; Hosahalli S; Mangamoori LN
    Mini Rev Med Chem; 2013 Oct; 13(11):1602-6. PubMed ID: 24000798
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Discovery of Bisindole as a Novel Scaffold for Protein Tyrosine Phosphatase 1B Inhibitors.
    Jing C; Li Z; Jia K; Chen C; Liu X; Wang B; Hu W; Li J; Zhu T; Dong S
    Arch Pharm (Weinheim); 2017 Jan; 350(1):. PubMed ID: 28029177
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Serendipitous discovery of light-induced (In Situ) formation of an Azo-bridged dimeric sulfonated naphthol as a potent PTP1B inhibitor.
    Bongard RD; Lepley M; Thakur K; Talipov MR; Nayak J; Lipinski RAJ; Bohl C; Sweeney N; Ramchandran R; Rathore R; Sem DS
    BMC Biochem; 2017 May; 18(1):10. PubMed ID: 28569147
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.