183 related articles for article (PubMed ID: 18216275)
1. Species differences in the response of liver drug-metabolizing enzymes to (S)-4-O-tolylsulfanyl-2-(4-trifluormethyl-phenoxy)-butyric acid (EMD 392949) in vivo and in vitro.
Richert L; Tuschl G; Viollon-Abadie C; Blanchard N; Bonet A; Heyd B; Halkic N; Wimmer E; Dolgos H; Mueller SO
Drug Metab Dispos; 2008 Apr; 36(4):702-14. PubMed ID: 18216275
[TBL] [Abstract][Full Text] [Related]
2. Species-specific activation of nuclear receptors correlates with the response of liver drug metabolizing enzymes to EMD 392949 in vitro.
Mueller SO; Fery Y; Tuschl G; Schrenk D
Toxicol Lett; 2010 Mar; 193(1):120-3. PubMed ID: 20035846
[TBL] [Abstract][Full Text] [Related]
3. Effects of Andrographis paniculata extract and Andrographolide on hepatic cytochrome P450 mRNA expression and monooxygenase activities after in vivo administration to rats and in vitro in rat and human hepatocyte cultures.
Pekthong D; Blanchard N; Abadie C; Bonet A; Heyd B; Mantion G; Berthelot A; Richert L; Martin H
Chem Biol Interact; 2009 May; 179(2-3):247-55. PubMed ID: 19041297
[TBL] [Abstract][Full Text] [Related]
4. Differential regulation of the cynomolgus, human, and rat acyl-CoA oxidase promoters by PPARalpha.
Kane CD; Francone OL; Stevens KA
Gene; 2006 Oct; 380(2):84-94. PubMed ID: 16828988
[TBL] [Abstract][Full Text] [Related]
5. Gene expression profiling of the PPAR-alpha agonist ciprofibrate in the cynomolgus monkey liver.
Cariello NF; Romach EH; Colton HM; Ni H; Yoon L; Falls JG; Casey W; Creech D; Anderson SP; Benavides GR; Hoivik DJ; Brown R; Miller RT
Toxicol Sci; 2005 Nov; 88(1):250-64. PubMed ID: 16081524
[TBL] [Abstract][Full Text] [Related]
6. Pharmacokinetics, disposition and lipid-modulating activity of 5-{2-[4-(3,4-difluorophenoxy)-phenyl]-ethylsulfamoyl}-2-methyl-benzoic acid, a potent and subtype-selective peroxisome proliferator-activated receptor alpha agonist in preclinical species and human.
Frederick KS; Maurer TS; Kalgutkar AS; Royer LJ; Francone OL; Winter SM; Terra SG; Chen D; Gao X
Xenobiotica; 2009 Oct; 39(10):766-81. PubMed ID: 19622022
[TBL] [Abstract][Full Text] [Related]
7. Species-specific toxicity of diclofenac and troglitazone in primary human and rat hepatocytes.
Lauer B; Tuschl G; Kling M; Mueller SO
Chem Biol Interact; 2009 Apr; 179(1):17-24. PubMed ID: 19022234
[TBL] [Abstract][Full Text] [Related]
8. Cytokines down-regulate expression of major cytochrome P-450 enzymes in adult human hepatocytes in primary culture.
Abdel-Razzak Z; Loyer P; Fautrel A; Gautier JC; Corcos L; Turlin B; Beaune P; Guillouzo A
Mol Pharmacol; 1993 Oct; 44(4):707-15. PubMed ID: 8232220
[TBL] [Abstract][Full Text] [Related]
9. Temporal kinetics and concentration-response relationships for induction of CYP1A, CYP2B, and CYP3A in primary cultures of beagle dog hepatocytes.
Graham RA; Tyler LO; Krol WL; Silver IS; Webster LO; Clark P; Chen L; Banks T; LeCluyse EL
J Biochem Mol Toxicol; 2006; 20(2):69-78. PubMed ID: 16615094
[TBL] [Abstract][Full Text] [Related]
10. CYP2C76, a novel cytochrome P450 in cynomolgus monkey, is a major CYP2C in liver, metabolizing tolbutamide and testosterone.
Uno Y; Fujino H; Kito G; Kamataki T; Nagata R
Mol Pharmacol; 2006 Aug; 70(2):477-86. PubMed ID: 16648389
[TBL] [Abstract][Full Text] [Related]
11. Use of mRNA expression to detect the induction of drug metabolising enzymes in rat and human hepatocytes.
Richert L; Tuschl G; Abadie C; Blanchard N; Pekthong D; Mantion G; Weber JC; Mueller SO
Toxicol Appl Pharmacol; 2009 Feb; 235(1):86-96. PubMed ID: 19118567
[TBL] [Abstract][Full Text] [Related]
12. Comparative gene expression profiles induced by PPARγ and PPARα/γ agonists in rat hepatocytes.
Rogue A; Renaud MP; Claude N; Guillouzo A; Spire C
Toxicol Appl Pharmacol; 2011 Jul; 254(1):18-31. PubMed ID: 21515302
[TBL] [Abstract][Full Text] [Related]
13. Comparison of the induction of hepatic peroxisome proliferation by the herbicide oxadiazon in vivo in rats, mice, and dogs and in vitro in rat and human hepatocytes.
Richert L; Price S; Chesne C; Maita K; Carmichael N
Toxicol Appl Pharmacol; 1996 Nov; 141(1):35-43. PubMed ID: 8917673
[TBL] [Abstract][Full Text] [Related]
14. Induction of peroxisome proliferator-activated receptor alpha (PPARalpha)-related enzymes by di(2-ethylhexyl) phthalate (DEHP) treatment in mice and rats, but not marmosets.
Ito Y; Yamanoshita O; Kurata Y; Kamijima M; Aoyama T; Nakajima T
Arch Toxicol; 2007 Mar; 81(3):219-26. PubMed ID: 16937134
[TBL] [Abstract][Full Text] [Related]
15. Sex-dependent metabolism of xenobiotics.
Mugford CA; Kedderis GL
Drug Metab Rev; 1998 Aug; 30(3):441-98. PubMed ID: 9710703
[TBL] [Abstract][Full Text] [Related]
16. Gene expression analysis in rats treated with experimental acetyl-coenzyme A carboxylase inhibitors suggests interactions with the peroxisome proliferator-activated receptor alpha pathway.
Waring JF; Yang Y; Healan-Greenberg CH; Adler AL; Dickinson R; McNally T; Wang X; Weitzberg M; Xu X; Lisowski A; Warder SE; Gu YG; Zinker BA; Blomme EA; Camp HS
J Pharmacol Exp Ther; 2008 Feb; 324(2):507-16. PubMed ID: 18025247
[TBL] [Abstract][Full Text] [Related]
17. In vivo induction of human cytochrome P450 enzymes expressed in chimeric mice with humanized liver.
Katoh M; Matsui T; Nakajima M; Tateno C; Soeno Y; Horie T; Iwasaki K; Yoshizato K; Yokoi T
Drug Metab Dispos; 2005 Jun; 33(6):754-63. PubMed ID: 15769886
[TBL] [Abstract][Full Text] [Related]
18. Expression and inducibility of P450 enzymes during liver ontogeny.
Rich KJ; Boobis AR
Microsc Res Tech; 1997 Dec; 39(5):424-35. PubMed ID: 9408909
[TBL] [Abstract][Full Text] [Related]
19. Serum-free collagen sandwich cultures of adult rat hepatocytes maintain liver-like properties long term: a valuable model for in vitro toxicity and drug-drug interaction studies.
Tuschl G; Hrach J; Walter Y; Hewitt PG; Mueller SO
Chem Biol Interact; 2009 Sep; 181(1):124-37. PubMed ID: 19482013
[TBL] [Abstract][Full Text] [Related]
20. Biochemical and morphological effects of K-111, a peroxisome proliferator-activated receptor (PPAR)alpha activator, in non-human primates.
Schäfer SA; Hansen BC; Völkl A; Fahimi HD; Pill J
Biochem Pharmacol; 2004 Jul; 68(2):239-51. PubMed ID: 15193996
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
