BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

257 related articles for article (PubMed ID: 18220785)

  • 1. The role and significance of unconventional hydrogen bonds in small molecule recognition by biological receptors of pharmaceutical relevance.
    Tóth G; Bowers SG; Truong AP; Probst G
    Curr Pharm Des; 2007; 13(34):3476-93. PubMed ID: 18220785
    [TBL] [Abstract][Full Text] [Related]  

  • 2. From drug target to leads--sketching a physicochemical pathway for lead molecule design in silico.
    Shaikh SA; Jain T; Sandhu G; Latha N; Jayaram B
    Curr Pharm Des; 2007; 13(34):3454-70. PubMed ID: 18220783
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Molecular determinants of drug-receptor binding kinetics.
    Pan AC; Borhani DW; Dror RO; Shaw DE
    Drug Discov Today; 2013 Jul; 18(13-14):667-73. PubMed ID: 23454741
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Lead optimization via high-throughput molecular docking.
    Joseph-McCarthy D; Baber JC; Feyfant E; Thompson DC; Humblet C
    Curr Opin Drug Discov Devel; 2007 May; 10(3):264-74. PubMed ID: 17554852
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Ranking poses in structure-based lead discovery and optimization: current trends in scoring function development.
    Rajamani R; Good AC
    Curr Opin Drug Discov Devel; 2007 May; 10(3):308-15. PubMed ID: 17554857
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Molecular modeling of hydration in drug design.
    Mancera RL
    Curr Opin Drug Discov Devel; 2007 May; 10(3):275-80. PubMed ID: 17554853
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Informatics and modeling challenges in fragment-based drug discovery.
    Hubbard RE; Chen I; Davis B
    Curr Opin Drug Discov Devel; 2007 May; 10(3):289-97. PubMed ID: 17554855
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Physics-based methods for studying protein-ligand interactions.
    Huang N; Jacobson MP
    Curr Opin Drug Discov Devel; 2007 May; 10(3):325-31. PubMed ID: 17554859
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Intramolecular hydrogen bonding in medicinal chemistry.
    Kuhn B; Mohr P; Stahl M
    J Med Chem; 2010 Mar; 53(6):2601-11. PubMed ID: 20175530
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Chemogenomic approaches to drug discovery: similar receptors bind similar ligands.
    Klabunde T
    Br J Pharmacol; 2007 Sep; 152(1):5-7. PubMed ID: 17533415
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The use of protein-ligand interaction fingerprints in docking.
    Brewerton SC
    Curr Opin Drug Discov Devel; 2008 May; 11(3):356-64. PubMed ID: 18428089
    [TBL] [Abstract][Full Text] [Related]  

  • 12. C-H...O hydrogen bonds in the nuclear receptor RARgamma--a potential tool for drug selectivity.
    Klaholz B; Moras D
    Structure; 2002 Sep; 10(9):1197-204. PubMed ID: 12220491
    [TBL] [Abstract][Full Text] [Related]  

  • 13. N-H...O, O-H...O, and C-H...O hydrogen bonds in protein-ligand complexes: strong and weak interactions in molecular recognition.
    Sarkhel S; Desiraju GR
    Proteins; 2004 Feb; 54(2):247-59. PubMed ID: 14696187
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Protein-ligand interfaces are polarized: discovery of a strong trend for intermolecular hydrogen bonds to favor donors on the protein side with implications for predicting and designing ligand complexes.
    Raschka S; Wolf AJ; Bemister-Buffington J; Kuhn LA
    J Comput Aided Mol Des; 2018 Apr; 32(4):511-528. PubMed ID: 29435780
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Molecular optimization using computational multi-objective methods.
    Nicolaou CA; Brown N; Pattichis CS
    Curr Opin Drug Discov Devel; 2007 May; 10(3):316-24. PubMed ID: 17554858
    [TBL] [Abstract][Full Text] [Related]  

  • 16. In silico identification of bioisosteric functional groups.
    Ertl P
    Curr Opin Drug Discov Devel; 2007 May; 10(3):281-8. PubMed ID: 17554854
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Nonbonding interactions of organic halogens in biological systems: implications for drug discovery and biomolecular design.
    Lu Y; Wang Y; Zhu W
    Phys Chem Chem Phys; 2010 May; 12(18):4543-51. PubMed ID: 20428531
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Investigation of atomic level patterns in protein--small ligand interactions.
    Chen K; Kurgan L
    PLoS One; 2009; 4(2):e4473. PubMed ID: 19221587
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Non-covalent interactions with aromatic rings: current understanding and implications for rational drug design.
    Li S; Xu Y; Shen Q; Liu X; Lu J; Chen Y; Lu T; Luo C; Luo X; Zheng M; Jiang H
    Curr Pharm Des; 2013; 19(36):6522-33. PubMed ID: 23772607
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Pocket extraction on proteins via the Voronoi diagram of spheres.
    Kim D; Cho CH; Cho Y; Ryu J; Bhak J; Kim DS
    J Mol Graph Model; 2008 Apr; 26(7):1104-12. PubMed ID: 18023220
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.