These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

181 related articles for article (PubMed ID: 18221151)

  • 61. Absence of primary integrase resistance mutations in HIV type 1-infected patients in Venezuela.
    Rangel HR; Garzaro D; Fabbro R; Martinez N; Ossenkop J; Torres JR; Gutiérrez CR; Pujol FH
    AIDS Res Hum Retroviruses; 2010 Aug; 26(8):923-6. PubMed ID: 20704494
    [TBL] [Abstract][Full Text] [Related]  

  • 62. HIV integrase inhibitors: from diketoacids to heterocyclic templates: a history of HIV integrase medicinal chemistry at Merck West Point and Merck Rome (IRBM).
    Egbertson MS
    Curr Top Med Chem; 2007; 7(13):1251-72. PubMed ID: 17627556
    [TBL] [Abstract][Full Text] [Related]  

  • 63. Azido-containing aryl beta-diketo acid HIV-1 integrase inhibitors.
    Zhang X; Pais GC; Svarovskaia ES; Marchand C; Johnson AA; Karki RG; Nicklaus MC; Pathak VK; Pommier Y; Burke TR
    Bioorg Med Chem Lett; 2003 Mar; 13(6):1215-9. PubMed ID: 12643946
    [TBL] [Abstract][Full Text] [Related]  

  • 64. Resistance against Integrase Strand Transfer Inhibitors and Relevance to HIV Persistence.
    Mesplède T; Wainberg MA
    Viruses; 2015 Jul; 7(7):3703-18. PubMed ID: 26198244
    [TBL] [Abstract][Full Text] [Related]  

  • 65. HIV-1 Resistance to Dolutegravir Is Affected by Cellular Histone Acetyltransferase Activity.
    Anstett K; Brenner B; Mesplède T; Wainberg MA
    J Virol; 2017 Nov; 91(21):. PubMed ID: 28835492
    [TBL] [Abstract][Full Text] [Related]  

  • 66. 4-Hydroxy-5-pyrrolinone-3-carboxamide HIV-1 integrase inhibitors.
    Pace P; Spieser SA; Summa V
    Bioorg Med Chem Lett; 2008 Jul; 18(14):3865-9. PubMed ID: 18595690
    [TBL] [Abstract][Full Text] [Related]  

  • 67. HIV-1 integrase inhibitors: a decade of research and two drugs in clinical trial.
    Johnson AA; Marchand C; Pommier Y
    Curr Top Med Chem; 2004; 4(10):1059-77. PubMed ID: 15193139
    [TBL] [Abstract][Full Text] [Related]  

  • 68. Oligonucleotides as inhibitors of human immunodeficiency virus.
    Field AK
    Curr Opin Mol Ther; 1999 Jun; 1(3):323-31. PubMed ID: 11713797
    [TBL] [Abstract][Full Text] [Related]  

  • 69. Exploration of the diketoacid integrase inhibitor chemotype leading to the discovery of the anilide-ketoacids chemotype.
    Walker MA; Johnson T; Ma Z; Zhang Y; Banville J; Remillard R; Plamondon S; Pendri A; Wong H; Smith D; Torri A; Samanta H; Lin Z; Deminie C; Terry B; Krystal M; Meanwell N
    Bioorg Med Chem Lett; 2006 Nov; 16(22):5818-21. PubMed ID: 16971121
    [TBL] [Abstract][Full Text] [Related]  

  • 70. Synthesis, docking, and biological studies of phenanthrene β-diketo acids as novel HIV-1 integrase inhibitors.
    Sharma H; Sanchez TW; Neamati N; Detorio M; Schinazi RF; Cheng X; Buolamwini JK
    Bioorg Med Chem Lett; 2013 Nov; 23(22):6146-51. PubMed ID: 24091080
    [TBL] [Abstract][Full Text] [Related]  

  • 71. Design and synthesis of dual inhibitors of HIV reverse transcriptase and integrase: introducing a diketoacid functionality into delavirdine.
    Wang Z; Vince R
    Bioorg Med Chem; 2008 Apr; 16(7):3587-95. PubMed ID: 18314335
    [TBL] [Abstract][Full Text] [Related]  

  • 72. Emerging patterns and implications of HIV-1 integrase inhibitor resistance.
    Geretti AM; Armenia D; Ceccherini-Silberstein F
    Curr Opin Infect Dis; 2012 Dec; 25(6):677-86. PubMed ID: 23086187
    [TBL] [Abstract][Full Text] [Related]  

  • 73. Specific features of HIV-1 integrase inhibition by bisphosphonate derivatives.
    Agapkina J; Yanvarev D; Anisenko A; Korolev S; Vepsäläinen J; Kochetkov S; Gottikh M
    Eur J Med Chem; 2014 Feb; 73():73-82. PubMed ID: 24378711
    [TBL] [Abstract][Full Text] [Related]  

  • 74. The M184I/V and K65R nucleoside resistance mutations in HIV-1 prevent the emergence of resistance mutations against dolutegravir.
    Oliveira M; Ibanescu RI; Pham HT; Brenner B; Mesplède T; Wainberg MA
    AIDS; 2016 Sep; 30(15):2267-73. PubMed ID: 27367488
    [TBL] [Abstract][Full Text] [Related]  

  • 75. Diketoacid inhibitors of HIV-1 integrase: from L-708,906 to raltegravir and beyond.
    Beare KD; Coster MJ; Rutledge PJ
    Curr Med Chem; 2012; 19(8):1177-92. PubMed ID: 22214459
    [TBL] [Abstract][Full Text] [Related]  

  • 76. New insights into the interaction between pyrrolyl diketoacids and HIV-1 integrase active site and comparison with RNase H.
    Corona A; di Leva FS; Rigogliuso G; Pescatori L; Madia VN; Subra F; Delelis O; Esposito F; Cadeddu M; Costi R; Cosconati S; Novellino E; di Santo R; Tramontano E
    Antiviral Res; 2016 Oct; 134():236-243. PubMed ID: 27659398
    [TBL] [Abstract][Full Text] [Related]  

  • 77. Selection of diverse and clinically relevant integrase inhibitor-resistant human immunodeficiency virus type 1 mutants.
    Kobayashi M; Nakahara K; Seki T; Miki S; Kawauchi S; Suyama A; Wakasa-Morimoto C; Kodama M; Endoh T; Oosugi E; Matsushita Y; Murai H; Fujishita T; Yoshinaga T; Garvey E; Foster S; Underwood M; Johns B; Sato A; Fujiwara T
    Antiviral Res; 2008 Nov; 80(2):213-22. PubMed ID: 18625269
    [TBL] [Abstract][Full Text] [Related]  

  • 78. Inhibition of HIV-1 integrase by small molecules: the potential for a new class of AIDS chemotherapeutics.
    Young SD
    Curr Opin Drug Discov Devel; 2001 Jul; 4(4):402-10. PubMed ID: 11727305
    [TBL] [Abstract][Full Text] [Related]  

  • 79. Synthesis, biological evaluation and molecular docking of calix[4]arene-based β-diketo derivatives as HIV-1 integrase inhibitors.
    Luo Z; Zhao Y; Ma C; Li Z; Xu X; Hu L; Huang N; He H
    Arch Pharm (Weinheim); 2015 Mar; 348(3):206-13. PubMed ID: 25682937
    [TBL] [Abstract][Full Text] [Related]  

  • 80. From ligand to complexes: inhibition of human immunodeficiency virus type 1 integrase by beta-diketo acid metal complexes.
    Sechi M; Bacchi A; Carcelli M; Compari C; Duce E; Fisicaro E; Rogolino D; Gates P; Derudas M; Al-Mawsawi LQ; Neamati N
    J Med Chem; 2006 Jul; 49(14):4248-60. PubMed ID: 16821784
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 10.