These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

509 related articles for article (PubMed ID: 18221220)

  • 1. Advances in the discovery of novel positive allosteric modulators of the alpha7 nicotinic acetylcholine receptor.
    Faghih R; Gfesser GA; Gopalakrishnan M
    Recent Pat CNS Drug Discov; 2007 Jun; 2(2):99-106. PubMed ID: 18221220
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Distinct profiles of alpha7 nAChR positive allosteric modulation revealed by structurally diverse chemotypes.
    Grønlien JH; Håkerud M; Ween H; Thorin-Hagene K; Briggs CA; Gopalakrishnan M; Malysz J
    Mol Pharmacol; 2007 Sep; 72(3):715-24. PubMed ID: 17565004
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Positive allosteric modulators of alpha 7 nicotinic acetylcholine receptors reverse ketamine-induced schizophrenia-like deficits in rats.
    Nikiforuk A; Kos T; Hołuj M; Potasiewicz A; Popik P
    Neuropharmacology; 2016 Feb; 101():389-400. PubMed ID: 26232639
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Evaluation of alpha7 nicotinic acetylcholine receptor agonists and positive allosteric modulators using the parallel oocyte electrophysiology test station.
    Malysz J; Grønlien JH; Timmermann DB; Håkerud M; Thorin-Hagene K; Ween H; Trumbull JD; Xiong Y; Briggs CA; Ahring PK; Dyhring T; Gopalakrishnan M
    Assay Drug Dev Technol; 2009 Aug; 7(4):374-90. PubMed ID: 19689206
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Potentiation and allosteric agonist activation of α7 nicotinic acetylcholine receptors: binding sites and hypotheses.
    Sanders VR; Millar NS
    Pharmacol Res; 2023 May; 191():106759. PubMed ID: 37023990
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The novel alpha7 nicotinic acetylcholine receptor agonist N-[(3R)-1-azabicyclo[2.2.2]oct-3-yl]-7-[2-(methoxy)phenyl]-1-benzofuran-2-carboxamide improves working and recognition memory in rodents.
    Boess FG; De Vry J; Erb C; Flessner T; Hendrix M; Luithle J; Methfessel C; Riedl B; Schnizler K; van der Staay FJ; van Kampen M; Wiese WB; Koenig G
    J Pharmacol Exp Ther; 2007 May; 321(2):716-25. PubMed ID: 17308038
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Structurally similar allosteric modulators of α7 nicotinic acetylcholine receptors exhibit five distinct pharmacological effects.
    Gill-Thind JK; Dhankher P; D'Oyley JM; Sheppard TD; Millar NS
    J Biol Chem; 2015 Feb; 290(6):3552-62. PubMed ID: 25516597
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Selective activation of α7 nicotinic acetylcholine receptor by PHA-543613 improves Aβ25-35-mediated cognitive deficits in mice.
    Sadigh-Eteghad S; Talebi M; Mahmoudi J; Babri S; Shanehbandi D
    Neuroscience; 2015 Jul; 298():81-93. PubMed ID: 25881725
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Molecular interactions of type I and type II positive allosteric modulators with the human α7 nicotinic acetylcholine receptor: an in silico study.
    Targowska-Duda KM; Kaczor AA; Jozwiak K; Arias HR
    J Biomol Struct Dyn; 2019 Feb; 37(2):411-439. PubMed ID: 29363414
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Positive allosteric modulators of α7* or β2* nicotinic acetylcholine receptors trigger different kinase pathways in mitochondria.
    Uspenska K; Lykhmus O; Arias HR; Pons S; Maskos U; Komisarenko S; Skok M
    Int J Biochem Cell Biol; 2018 Jun; 99():226-235. PubMed ID: 29704624
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Pharmacological Characterization of the Novel and Selective
    Wang X; Daley C; Gakhar V; Lange HS; Vardigan JD; Pearson M; Zhou X; Warren L; Miller CO; Belden M; Harvey AJ; Grishin AA; Coles CJ; O'Connor SM; Thomson F; Duffy JL; Bell IM; Uslaner JM
    J Pharmacol Exp Ther; 2020 May; 373(2):311-324. PubMed ID: 32094294
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Cognitive improvement by activation of alpha7 nicotinic acetylcholine receptors: from animal models to human pathophysiology.
    Thomsen MS; Hansen HH; Timmerman DB; Mikkelsen JD
    Curr Pharm Des; 2010 Jan; 16(3):323-43. PubMed ID: 20109142
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Activators of α7 nAChR as Potential Therapeutics for Cognitive Impairment.
    Wang X; Bell IM; Uslaner JM
    Curr Top Behav Neurosci; 2020; 45():209-245. PubMed ID: 32451955
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Identification by virtual screening and functional characterisation of novel positive and negative allosteric modulators of the α7 nicotinic acetylcholine receptor.
    Smelt CLC; Sanders VR; Newcombe J; Burt RP; Sheppard TD; Topf M; Millar NS
    Neuropharmacology; 2018 Sep; 139():194-204. PubMed ID: 30009834
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Positive allosteric modulation of alpha7 neuronal nicotinic acetylcholine receptors: lack of cytotoxicity in PC12 cells and rat primary cortical neurons.
    Hu M; Gopalakrishnan M; Li J
    Br J Pharmacol; 2009 Dec; 158(8):1857-64. PubMed ID: 20050184
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The α7 nicotinic acetylcholine receptor complex: one, two or multiple drug targets?
    Thomsen MS; Mikkelsen JD
    Curr Drug Targets; 2012 May; 13(5):707-20. PubMed ID: 22300038
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The combination of memantine and galantamine improves cognition in rats: The synergistic role of the α7 nicotinic acetylcholine and NMDA receptors.
    Nikiforuk A; Potasiewicz A; Kos T; Popik P
    Behav Brain Res; 2016 Oct; 313():214-218. PubMed ID: 27435422
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Chemical conversion of nicotinamide into type I positive allosteric modulator of α7 nAChRs.
    Li X; Xie W; Wang X; Huang Z; Bian X; Wang K; Sun Q
    Bioorg Med Chem Lett; 2019 Aug; 29(15):1928-1933. PubMed ID: 31153804
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Diverse strategies targeting α7 homomeric and α6β2* heteromeric nicotinic acetylcholine receptors for smoking cessation.
    Brunzell DH; McIntosh JM; Papke RL
    Ann N Y Acad Sci; 2014 Oct; 1327(1):27-45. PubMed ID: 24730978
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Differential immediate and sustained memory enhancing effects of alpha7 nicotinic receptor agonists and allosteric modulators in rats.
    Thomsen MS; El-Sayed M; Mikkelsen JD
    PLoS One; 2011; 6(11):e27014. PubMed ID: 22096516
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 26.