These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

252 related articles for article (PubMed ID: 18223670)

  • 1. Agonist binding, agonist affinity and agonist efficacy at G protein-coupled receptors.
    Strange PG
    Br J Pharmacol; 2008 Apr; 153(7):1353-63. PubMed ID: 18223670
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Estimation of the receptor-state affinity constants of ligands in functional studies using wild type and constitutively active mutant receptors: Implications for estimation of agonist bias.
    Ehlert FJ; Stein RS
    J Pharmacol Toxicol Methods; 2017; 83():94-106. PubMed ID: 27725245
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Quantifying agonist activity at G protein-coupled receptors.
    Ehlert FJ; Suga H; Griffin MT
    J Vis Exp; 2011 Dec; (58):e3179. PubMed ID: 22231636
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Quantifying biological activity in chemical terms: a pharmacology primer to describe drug effect.
    Kenakin T
    ACS Chem Biol; 2009 Apr; 4(4):249-60. PubMed ID: 19193052
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Unravelling intrinsic efficacy and ligand bias at G protein coupled receptors: A practical guide to assessing functional data.
    Stott LA; Hall DA; Holliday ND
    Biochem Pharmacol; 2016 Feb; 101():1-12. PubMed ID: 26478533
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Mechanisms underlying agonist efficacy.
    Strange PG
    Biochem Soc Trans; 2007 Aug; 35(Pt 4):733-6. PubMed ID: 17635136
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Functional studies cast light on receptor states.
    Ehlert FJ
    Trends Pharmacol Sci; 2015 Sep; 36(9):596-604. PubMed ID: 26123416
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Estimation of the affinities of allosteric ligands using radioligand binding and pharmacological null methods.
    Ehlert FJ
    Mol Pharmacol; 1988 Feb; 33(2):187-94. PubMed ID: 2828914
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Estimation of ligand affinity constants for receptor states in functional studies involving the allosteric modulation of G protein-coupled receptors: implications for ligand bias.
    Ehlert FJ; Griffin MT
    J Pharmacol Toxicol Methods; 2014; 69(3):253-79. PubMed ID: 24434717
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Being mindful of seven-transmembrane receptor 'guests' when assessing agonist selectivity.
    Kenakin T
    Br J Pharmacol; 2010 Jul; 160(5):1045-7. PubMed ID: 20590598
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Evaluation of Operational Models of Agonism and Allosterism at Receptors with Multiple Orthosteric Binding Sites.
    Gregory KJ; Giraldo J; Diao J; Christopoulos A; Leach K
    Mol Pharmacol; 2020 Jan; 97(1):35-45. PubMed ID: 31704718
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Novel insights into biased agonism at G protein-coupled receptors and their potential for drug design.
    Martí-Solano M; Guixà-González R; Sanz F; Pastor M; Selent J
    Curr Pharm Des; 2013; 19(28):5156-66. PubMed ID: 23621547
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Molecular basis for high-affinity agonist binding in GPCRs.
    Warne T; Edwards PC; Doré AS; Leslie AGW; Tate CG
    Science; 2019 May; 364(6442):775-778. PubMed ID: 31072904
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Agonism and inverse agonism at dopamine D2-like receptors.
    Strange PG
    Clin Exp Pharmacol Physiol Suppl; 1999 Apr; 26():S3-9. PubMed ID: 10386247
    [TBL] [Abstract][Full Text] [Related]  

  • 15. On the analysis of ligand-directed signaling at G protein-coupled receptors.
    Ehlert FJ
    Naunyn Schmiedebergs Arch Pharmacol; 2008 Jun; 377(4-6):549-77. PubMed ID: 18253722
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Identifying Functional Hotspot Residues for Biased Ligand Design in G-Protein-Coupled Receptors.
    Nivedha AK; Tautermann CS; Bhattacharya S; Lee S; Casarosa P; Kollak I; Kiechle T; Vaidehi N
    Mol Pharmacol; 2018 Apr; 93(4):288-296. PubMed ID: 29367258
    [TBL] [Abstract][Full Text] [Related]  

  • 17. A kinetic model of GPCRs: analysis of G protein activity, occupancy, coupling and receptor-state affinity constants.
    Stein RS; Ehlert FJ
    J Recept Signal Transduct Res; 2015; 35(4):269-83. PubMed ID: 25353707
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Analysis of functional responses at G protein-coupled receptors: estimation of relative affinity constants for the inactive receptor state.
    Ehlert FJ; Griffin MT; Suga H
    J Pharmacol Exp Ther; 2011 Aug; 338(2):658-70. PubMed ID: 21576380
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Photolabelling the urotensin II receptor reveals distinct agonist- and partial-agonist-binding sites.
    Holleran BJ; Beaulieu ME; Proulx CD; Lavigne P; Escher E; Leduc R
    Biochem J; 2007 Feb; 402(1):51-61. PubMed ID: 17064254
    [TBL] [Abstract][Full Text] [Related]  

  • 20. When simple agonism is not enough: emerging modalities of GPCR ligands.
    Smith NJ; Bennett KA; Milligan G
    Mol Cell Endocrinol; 2011 Jan; 331(2):241-7. PubMed ID: 20654693
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.