211 related articles for article (PubMed ID: 18230605)
1. Betaine-homocysteine S-methyltransferase-2 is an S-methylmethionine-homocysteine methyltransferase.
Szegedi SS; Castro CC; Koutmos M; Garrow TA
J Biol Chem; 2008 Apr; 283(14):8939-45. PubMed ID: 18230605
[TBL] [Abstract][Full Text] [Related]
2. Specific potassium ion interactions facilitate homocysteine binding to betaine-homocysteine S-methyltransferase.
Mládková J; Hladílková J; Diamond CE; Tryon K; Yamada K; Garrow TA; Jungwirth P; Koutmos M; Jiráček J
Proteins; 2014 Oct; 82(10):2552-64. PubMed ID: 24895213
[TBL] [Abstract][Full Text] [Related]
3. Double-headed sulfur-linked amino acids as first inhibitors for betaine-homocysteine S-methyltransferase 2.
Mládková J; Vaněk V; Buděšínský M; Elbert T; Demianová Z; Garrow TA; Jiráček J
J Med Chem; 2012 Aug; 55(15):6822-31. PubMed ID: 22775318
[TBL] [Abstract][Full Text] [Related]
4. Dissecting the catalytic mechanism of betaine-homocysteine S-methyltransferase by use of intrinsic tryptophan fluorescence and site-directed mutagenesis.
Castro C; Gratson AA; Evans JC; Jiracek J; Collinsová M; Ludwig ML; Garrow TA
Biochemistry; 2004 May; 43(18):5341-51. PubMed ID: 15122900
[TBL] [Abstract][Full Text] [Related]
5. Expression of recombinant human betaine: homocysteine S-methyltransferase for x-ray crystallographic studies and further characterization of interaction with S-adenosylmethionine.
Bose N; Greenspan P; Momany C
Protein Expr Purif; 2002 Jun; 25(1):73-80. PubMed ID: 12071701
[TBL] [Abstract][Full Text] [Related]
6. Betaine homocysteine methyltransferase is active in the mouse blastocyst and promotes inner cell mass development.
Lee MB; Kooistra M; Zhang B; Slow S; Fortier AL; Garrow TA; Lever M; Trasler JM; Baltz JM
J Biol Chem; 2012 Sep; 287(39):33094-103. PubMed ID: 22847001
[TBL] [Abstract][Full Text] [Related]
7. Mechanisms of protection by the betaine-homocysteine methyltransferase/betaine system in HepG2 cells and primary mouse hepatocytes.
Ji C; Shinohara M; Kuhlenkamp J; Chan C; Kaplowitz N
Hepatology; 2007 Nov; 46(5):1586-96. PubMed ID: 17705221
[TBL] [Abstract][Full Text] [Related]
8. Conformation-dependent inactivation of human betaine-homocysteine S-methyltransferase by hydrogen peroxide in vitro.
Miller CM; Szegedi SS; Garrow TA
Biochem J; 2005 Dec; 392(Pt 3):443-8. PubMed ID: 16038618
[TBL] [Abstract][Full Text] [Related]
9. Betaine homocysteine S-methyltransferase: just a regulator of homocysteine metabolism?
Pajares MA; Pérez-Sala D
Cell Mol Life Sci; 2006 Dec; 63(23):2792-803. PubMed ID: 17086380
[TBL] [Abstract][Full Text] [Related]
10. The BHMT-betaine methylation pathway epigenetically modulates oligodendrocyte maturation.
Sternbach S; West N; Singhal NK; Clements R; Basu S; Tripathi A; Dutta R; Freeman EJ; McDonough J
PLoS One; 2021; 16(5):e0250486. PubMed ID: 33975330
[TBL] [Abstract][Full Text] [Related]
11. Effects of diabetes and insulin on betaine-homocysteine S-methyltransferase expression in rat liver.
Ratnam S; Wijekoon EP; Hall B; Garrow TA; Brosnan ME; Brosnan JT
Am J Physiol Endocrinol Metab; 2006 May; 290(5):E933-9. PubMed ID: 16352668
[TBL] [Abstract][Full Text] [Related]
12. Splicing variants of the porcine betaine-homocysteine S-methyltransferase gene: implications for mammalian metabolism.
Ganu R; Garrow T; Koutmos M; Rund L; Schook LB
Gene; 2013 Oct; 529(2):228-37. PubMed ID: 23948084
[TBL] [Abstract][Full Text] [Related]
13. Inhibition of betaine-homocysteine S-methyltransferase in rats causes hyperhomocysteinemia and reduces liver cystathionine β-synthase activity and methylation capacity.
Strakova J; Gupta S; Kruger WD; Dilger RN; Tryon K; Li L; Garrow TA
Nutr Res; 2011 Jul; 31(7):563-71. PubMed ID: 21840473
[TBL] [Abstract][Full Text] [Related]
14. Deletion of betaine-homocysteine S-methyltransferase in mice perturbs choline and 1-carbon metabolism, resulting in fatty liver and hepatocellular carcinomas.
Teng YW; Mehedint MG; Garrow TA; Zeisel SH
J Biol Chem; 2011 Oct; 286(42):36258-67. PubMed ID: 21878621
[TBL] [Abstract][Full Text] [Related]
15. Human betaine-homocysteine methyltransferase is a zinc metalloenzyme.
Millian NS; Garrow TA
Arch Biochem Biophys; 1998 Aug; 356(1):93-8. PubMed ID: 9681996
[TBL] [Abstract][Full Text] [Related]
16. Inhibition of human betaine-homocysteine methyltransferase expression by S-adenosylmethionine and methylthioadenosine.
Ou X; Yang H; Ramani K; Ara AI; Chen H; Mato JM; Lu SC
Biochem J; 2007 Jan; 401(1):87-96. PubMed ID: 16953798
[TBL] [Abstract][Full Text] [Related]
17. The development of a new class of inhibitors for betaine-homocysteine S-methyltransferase.
Pícha J; Vaněk V; Buděšínský M; Mládková J; Garrow TA; Jiráček J
Eur J Med Chem; 2013 Jul; 65():256-75. PubMed ID: 23727536
[TBL] [Abstract][Full Text] [Related]
18. Dietary intake of S-(alpha-carboxybutyl)-DL-homocysteine induces hyperhomocysteinemia in rats.
Strakova J; Williams KT; Gupta S; Schalinske KL; Kruger WD; Rozen R; Jiracek J; Li L; Garrow TA
Nutr Res; 2010 Jul; 30(7):492-500. PubMed ID: 20797482
[TBL] [Abstract][Full Text] [Related]
19. Structure-activity study of new inhibitors of human betaine-homocysteine S-methyltransferase.
Vanek V; Budesínský M; Kabeleová P; Sanda M; Kozísek M; Hanclová I; Mládková J; Brynda J; Rosenberg I; Koutmos M; Garrow TA; Jirácek J
J Med Chem; 2009 Jun; 52(12):3652-65. PubMed ID: 19534555
[TBL] [Abstract][Full Text] [Related]
20. Alleviation of hepatic fat accumulation by betaine involves reduction of homocysteine via up-regulation of betaine-homocysteine methyltransferase (BHMT).
Ahn CW; Jun DS; Na JD; Choi YJ; Kim YC
Biochem Biophys Res Commun; 2016 Aug; 477(3):440-7. PubMed ID: 27320863
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
