BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

182 related articles for article (PubMed ID: 18230607)

  • 1. Small molecules destabilize cIAP1 by activating auto-ubiquitylation.
    Sekine K; Takubo K; Kikuchi R; Nishimoto M; Kitagawa M; Abe F; Nishikawa K; Tsuruo T; Naito M
    J Biol Chem; 2008 Apr; 283(14):8961-8. PubMed ID: 18230607
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Modulation of RIP1 ubiquitylation and distribution by MeBS to sensitize cancer cells to tumor necrosis factor α-induced apoptosis.
    Kim S; Ohoka N; Okuhira K; Sai K; Nishimaki-Mogami T; Naito M
    Cancer Sci; 2010 Nov; 101(11):2425-9. PubMed ID: 20825417
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Specific degradation of CRABP-II via cIAP1-mediated ubiquitylation induced by hybrid molecules that crosslink cIAP1 and the target protein.
    Okuhira K; Ohoka N; Sai K; Nishimaki-Mogami T; Itoh Y; Ishikawa M; Hashimoto Y; Naito M
    FEBS Lett; 2011 Apr; 585(8):1147-52. PubMed ID: 21414315
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The RING domain of cIAP1 mediates the degradation of RING-bearing inhibitor of apoptosis proteins by distinct pathways.
    Cheung HH; Plenchette S; Kern CJ; Mahoney DJ; Korneluk RG
    Mol Biol Cell; 2008 Jul; 19(7):2729-40. PubMed ID: 18434593
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Demonstration of direct binding of cIAP1 degradation-promoting bestatin analogs to BIR3 domain: Synthesis and application of fluorescent bestatin ester analogs.
    Sato S; Aoyama H; Miyachi H; Naito M; Hashimoto Y
    Bioorg Med Chem Lett; 2008 Jun; 18(11):3354-8. PubMed ID: 18448338
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Inhibition of cIAP1 as a strategy for targeting c-MYC-driven oncogenic activity.
    Li H; Fang Y; Niu C; Cao H; Mi T; Zhu H; Yuan J; Zhu J
    Proc Natl Acad Sci U S A; 2018 Oct; 115(40):E9317-E9324. PubMed ID: 30181285
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The ubiquitin-associated domain of cellular inhibitor of apoptosis proteins facilitates ubiquitylation.
    Budhidarmo R; Day CL
    J Biol Chem; 2014 Sep; 289(37):25721-36. PubMed ID: 25065467
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Structure-based design and molecular profiling of Smac-mimetics selective for cellular IAPs.
    Corti A; Milani M; Lecis D; Seneci P; de Rosa M; Mastrangelo E; Cossu F
    FEBS J; 2018 Sep; 285(17):3286-3298. PubMed ID: 30055105
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Different Degradation Mechanisms of Inhibitor of Apoptosis Proteins (IAPs) by the Specific and Nongenetic IAP-Dependent Protein Eraser (SNIPER).
    Ohoka N; Ujikawa O; Shimokawa K; Sameshima T; Shibata N; Hattori T; Nara H; Cho N; Naito M
    Chem Pharm Bull (Tokyo); 2019 Mar; 67(3):203-209. PubMed ID: 30369550
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Inhibiting the inhibitors: Targeting anti-apoptotic proteins in cancer and therapy resistance.
    Shahar N; Larisch S
    Drug Resist Updat; 2020 Sep; 52():100712. PubMed ID: 32599435
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Recognition of Smac-mimetic compounds by the BIR domain of cIAP1.
    Cossu F; Malvezzi F; Canevari G; Mastrangelo E; Lecis D; Delia D; Seneci P; Scolastico C; Bolognesi M; Milani M
    Protein Sci; 2010 Dec; 19(12):2418-29. PubMed ID: 20954235
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Chemosensitivity to HM90822, a novel synthetic IAP antagonist, is determined by p-AKT-inducible XIAP phosphorylation in human pancreatic cancer cells.
    Hong SW; Shin JS; Moon JH; Jung SA; Koh DI; Ryu Y; Park YS; Kim DY; Park SS; Hong JK; Kim EH; Kim MJ; Jeong HR; Bae IH; Ahn YG; Suh KH; Cho IJ; Kang JS; Hong YS; Lee JS; Jin DH; Kim TW
    Invest New Drugs; 2020 Dec; 38(6):1696-1706. PubMed ID: 32462369
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The Role of cIAP1 and XIAP in Apoptosis Induced by Tumor Necrosis Factor Alpha in Esophageal Squamous Cell Carcinoma Cells.
    Hikami S; Shiozaki A; Kitagawa-Juge M; Ichikawa D; Kosuga T; Konishi H; Komatsu S; Fujiwara H; Okamoto K; Otsuji E
    Dig Dis Sci; 2017 Mar; 62(3):652-659. PubMed ID: 28050781
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Ubiquitin-proteasome dependent regulation of Profilin2 (Pfn2) by a cellular inhibitor of apoptotic protein 1 (cIAP1).
    Jeong DH; Choi YN; Seo TW; Lee JS; Yoo SJ
    Biochem Biophys Res Commun; 2018 Nov; 506(3):423-428. PubMed ID: 30352681
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Ubiquitin binding modulates IAP antagonist-stimulated proteasomal degradation of c-IAP1 and c-IAP2(1).
    Blankenship JW; Varfolomeev E; Goncharov T; Fedorova AV; Kirkpatrick DS; Izrael-Tomasevic A; Phu L; Arnott D; Aghajan M; Zobel K; Bazan JF; Fairbrother WJ; Deshayes K; Vucic D
    Biochem J; 2009 Jan; 417(1):149-60. PubMed ID: 18939944
    [TBL] [Abstract][Full Text] [Related]  

  • 16. ASTX660, a Novel Non-peptidomimetic Antagonist of cIAP1/2 and XIAP, Potently Induces TNFα-Dependent Apoptosis in Cancer Cell Lines and Inhibits Tumor Growth.
    Ward GA; Lewis EJ; Ahn JS; Johnson CN; Lyons JF; Martins V; Munck JM; Rich SJ; Smyth T; Thompson NT; Williams PA; Wilsher NE; Wallis NG; Chessari G
    Mol Cancer Ther; 2018 Jul; 17(7):1381-1391. PubMed ID: 29695633
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Protein knockdown using methyl bestatin-ligand hybrid molecules: design and synthesis of inducers of ubiquitination-mediated degradation of cellular retinoic acid-binding proteins.
    Itoh Y; Ishikawa M; Naito M; Hashimoto Y
    J Am Chem Soc; 2010 Apr; 132(16):5820-6. PubMed ID: 20369832
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Cellular inhibitor of apoptosis protein 1 ubiquitinates endonuclease G but does not affect endonuclease G-mediated cell death.
    Seo TW; Lee JS; Yoo SJ
    Biochem Biophys Res Commun; 2014 Sep; 451(4):644-9. PubMed ID: 25139236
    [TBL] [Abstract][Full Text] [Related]  

  • 19.
    Ohoka N; Okuhira K; Ito M; Nagai K; Shibata N; Hattori T; Ujikawa O; Shimokawa K; Sano O; Koyama R; Fujita H; Teratani M; Matsumoto H; Imaeda Y; Nara H; Cho N; Naito M
    J Biol Chem; 2017 Mar; 292(11):4556-4570. PubMed ID: 28154167
    [TBL] [Abstract][Full Text] [Related]  

  • 20. SNIPERs-Hijacking IAP activity to induce protein degradation.
    Naito M; Ohoka N; Shibata N
    Drug Discov Today Technol; 2019 Apr; 31():35-42. PubMed ID: 31200857
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.