182 related articles for article (PubMed ID: 18230607)
21. LCL161 increases paclitaxel-induced apoptosis by degrading cIAP1 and cIAP2 in NSCLC.
Yang C; Wang H; Zhang B; Chen Y; Zhang Y; Sun X; Xiao G; Nan K; Ren H; Qin S
J Exp Clin Cancer Res; 2016 Sep; 35(1):158. PubMed ID: 27737687
[TBL] [Abstract][Full Text] [Related]
22. The F-box protein Fbxo7 interacts with human inhibitor of apoptosis protein cIAP1 and promotes cIAP1 ubiquitination.
Chang YF; Cheng CM; Chang LK; Jong YJ; Yuo CY
Biochem Biophys Res Commun; 2006 Apr; 342(4):1022-6. PubMed ID: 16510124
[TBL] [Abstract][Full Text] [Related]
23. Designing Smac-mimetics as antagonists of XIAP, cIAP1, and cIAP2.
Cossu F; Mastrangelo E; Milani M; Sorrentino G; Lecis D; Delia D; Manzoni L; Seneci P; Scolastico C; Bolognesi M
Biochem Biophys Res Commun; 2009 Jan; 378(2):162-7. PubMed ID: 18992220
[TBL] [Abstract][Full Text] [Related]
24. A discrete ubiquitin-mediated network regulates the strength of NOD2 signaling.
Tigno-Aranjuez JT; Bai X; Abbott DW
Mol Cell Biol; 2013 Jan; 33(1):146-58. PubMed ID: 23109427
[TBL] [Abstract][Full Text] [Related]
25. Inhibitors of apoptosis catch ubiquitin.
Rajalingam K; Dikic I
Biochem J; 2009 Jan; 417(1):e1-3. PubMed ID: 19061481
[TBL] [Abstract][Full Text] [Related]
26. Inhibitor of apoptosis proteins as novel targets in inflammatory processes.
Mayer BA; Rehberg M; Erhardt A; Wolf A; Reichel CA; Kracht M; Krombach F; Tiegs G; Zahler S; Vollmar AM; Fürst R
Arterioscler Thromb Vasc Biol; 2011 Oct; 31(10):2240-50. PubMed ID: 21817100
[TBL] [Abstract][Full Text] [Related]
27. Birinapant (TL32711), a bivalent SMAC mimetic, targets TRAF2-associated cIAPs, abrogates TNF-induced NF-κB activation, and is active in patient-derived xenograft models.
Benetatos CA; Mitsuuchi Y; Burns JM; Neiman EM; Condon SM; Yu G; Seipel ME; Kapoor GS; Laporte MG; Rippin SR; Deng Y; Hendi MS; Tirunahari PK; Lee YH; Haimowitz T; Alexander MD; Graham MA; Weng D; Shi Y; McKinlay MA; Chunduru SK
Mol Cancer Ther; 2014 Apr; 13(4):867-79. PubMed ID: 24563541
[TBL] [Abstract][Full Text] [Related]
28. Cancer cell death induced by novel small molecules degrading the TACC3 protein via the ubiquitin-proteasome pathway.
Ohoka N; Nagai K; Hattori T; Okuhira K; Shibata N; Cho N; Naito M
Cell Death Dis; 2014 Nov; 5(11):e1513. PubMed ID: 25375378
[TBL] [Abstract][Full Text] [Related]
29. Tumor necrosis factor-α-induced apoptosis of gastric cancer MKN28 cells: accelerated degradation of the inhibitor of apoptosis family members.
Kitagawa M; Shiozaki A; Ichikawa D; Nakashima S; Kosuga T; Konishi H; Komatsu S; Fujiwara H; Okamoto K; Otsuji E
Arch Biochem Biophys; 2015 Jan; 566():43-8. PubMed ID: 25513960
[TBL] [Abstract][Full Text] [Related]
30. cIAP1 and cIAP2 facilitate cancer cell survival by functioning as E3 ligases that promote RIP1 ubiquitination.
Bertrand MJ; Milutinovic S; Dickson KM; Ho WC; Boudreault A; Durkin J; Gillard JW; Jaquith JB; Morris SJ; Barker PA
Mol Cell; 2008 Jun; 30(6):689-700. PubMed ID: 18570872
[TBL] [Abstract][Full Text] [Related]
31. Stabilization of C-terminal binding protein 2 by cellular inhibitor of apoptosis protein 1 via BIR domains without E3 ligase activity.
Seo TW; Lee YT; Lee JS; Yoo SJ
Biochem Biophys Res Commun; 2020 Sep; 530(2):440-447. PubMed ID: 32553630
[TBL] [Abstract][Full Text] [Related]
32. Connective tissue growth factor confers drug resistance in breast cancer through concomitant up-regulation of Bcl-xL and cIAP1.
Wang MY; Chen PS; Prakash E; Hsu HC; Huang HY; Lin MT; Chang KJ; Kuo ML
Cancer Res; 2009 Apr; 69(8):3482-91. PubMed ID: 19351859
[TBL] [Abstract][Full Text] [Related]
33. A novel small-molecule IAP antagonist, AZD5582, draws Mcl-1 down-regulation for induction of apoptosis through targeting of cIAP1 and XIAP in human pancreatic cancer.
Moon JH; Shin JS; Hong SW; Jung SA; Hwang IY; Kim JH; Choi EK; Ha SH; Kim JS; Kim KM; Hong DW; Kim D; Kim YS; Kim JE; Kim KP; Hong YS; Choi EK; Lee JS; Hattersley M; Jin DH; Kim TW
Oncotarget; 2015 Sep; 6(29):26895-908. PubMed ID: 26314849
[TBL] [Abstract][Full Text] [Related]
34. E2F1 binds to the peptide-binding groove within the BIR3 domain of cIAP1 and requires cIAP1 for chromatin binding.
Allègre J; Cartier J; Glorian V; Droin N; Dumetier B; Kayaci C; Berthelet J; Gemble S; Vuillier C; Maillet L; Garrido C; Dubrez L
PLoS One; 2018; 13(10):e0206253. PubMed ID: 30359437
[TBL] [Abstract][Full Text] [Related]
35. Protein Knockdown Technology: Application of Ubiquitin Ligase to Cancer Therapy.
Ohoka N; Shibata N; Hattori T; Naito M
Curr Cancer Drug Targets; 2016; 16(2):136-46. PubMed ID: 26560118
[TBL] [Abstract][Full Text] [Related]
36. Design, synthesis, and biological activity of a potent Smac mimetic that sensitizes cancer cells to apoptosis by antagonizing IAPs.
Zobel K; Wang L; Varfolomeev E; Franklin MC; Elliott LO; Wallweber HJ; Okawa DC; Flygare JA; Vucic D; Fairbrother WJ; Deshayes K
ACS Chem Biol; 2006 Sep; 1(8):525-33. PubMed ID: 17168540
[TBL] [Abstract][Full Text] [Related]
37. Inhibitors of apoptosis proteins (IAPs) as potential molecular targets for therapy of hematological malignancies.
Smolewski P; Robak T
Curr Mol Med; 2011 Nov; 11(8):633-49. PubMed ID: 21902653
[TBL] [Abstract][Full Text] [Related]
38. Double protein knockdown of cIAP1 and CRABP-II using a hybrid molecule consisting of ATRA and IAPs antagonist.
Itoh Y; Ishikawa M; Kitaguchi R; Okuhira K; Naito M; Hashimoto Y
Bioorg Med Chem Lett; 2012 Jul; 22(13):4453-7. PubMed ID: 22658364
[TBL] [Abstract][Full Text] [Related]
39. IAPs as E3 ligases of Rac1: shaping the move.
Oberoi-Khanuja TK; Rajalingam K
Small GTPases; 2012; 3(2):131-6. PubMed ID: 22790203
[TBL] [Abstract][Full Text] [Related]
40. Development of protein degradation inducers of oncogenic BCR-ABL protein by conjugation of ABL kinase inhibitors and IAP ligands.
Shibata N; Miyamoto N; Nagai K; Shimokawa K; Sameshima T; Ohoka N; Hattori T; Imaeda Y; Nara H; Cho N; Naito M
Cancer Sci; 2017 Aug; 108(8):1657-1666. PubMed ID: 28556300
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]