219 related articles for article (PubMed ID: 18235222)
1. Unlocking the Mdm2-p53 loop: ubiquitin is the key.
Clegg HV; Itahana K; Zhang Y
Cell Cycle; 2008 Feb; 7(3):287-92. PubMed ID: 18235222
[TBL] [Abstract][Full Text] [Related]
2. Mdm2 RING mutation enhances p53 transcriptional activity and p53-p300 interaction.
Clegg HV; Itahana Y; Itahana K; Ramalingam S; Zhang Y
PLoS One; 2012; 7(5):e38212. PubMed ID: 22666487
[TBL] [Abstract][Full Text] [Related]
3. Regulation of the p53 tumor suppressor pathway: the problems and promises of studying Mdm2's E3 ligase function.
Clegg HV; Zhang Y
Crit Rev Eukaryot Gene Expr; 2010; 20(1):77-86. PubMed ID: 20528739
[TBL] [Abstract][Full Text] [Related]
4. MDM2 E3 ligase activity is essential for p53 regulation and cell cycle integrity.
Chinnam M; Xu C; Lama R; Zhang X; Cedeno CD; Wang Y; Stablewski AB; Goodrich DW; Wang X
PLoS Genet; 2022 May; 18(5):e1010171. PubMed ID: 35588102
[TBL] [Abstract][Full Text] [Related]
5. Cancer-associated mutations in the MDM2 zinc finger domain disrupt ribosomal protein interaction and attenuate MDM2-induced p53 degradation.
Lindström MS; Jin A; Deisenroth C; White Wolf G; Zhang Y
Mol Cell Biol; 2007 Feb; 27(3):1056-68. PubMed ID: 17116689
[TBL] [Abstract][Full Text] [Related]
6. Inactivation of the MDM2 RING domain enhances p53 transcriptional activity in mice.
Tian H; Tackmann NR; Jin A; Zheng J; Zhang Y
J Biol Chem; 2017 Dec; 292(52):21614-21622. PubMed ID: 29123033
[TBL] [Abstract][Full Text] [Related]
7. Identification of a Catalytic Active but Non-Aggregating MDM2 RING Domain Variant.
Magnussen HM; Huang DT
J Mol Biol; 2021 Mar; 433(5):166807. PubMed ID: 33450248
[TBL] [Abstract][Full Text] [Related]
8. Structural analysis of MDM2 RING separates degradation from regulation of p53 transcription activity.
Nomura K; Klejnot M; Kowalczyk D; Hock AK; Sibbet GJ; Vousden KH; Huang DT
Nat Struct Mol Biol; 2017 Jul; 24(7):578-587. PubMed ID: 28553961
[TBL] [Abstract][Full Text] [Related]
9. Targeted inactivation of Mdm2 RING finger E3 ubiquitin ligase activity in the mouse reveals mechanistic insights into p53 regulation.
Itahana K; Mao H; Jin A; Itahana Y; Clegg HV; Lindström MS; Bhat KP; Godfrey VL; Evan GI; Zhang Y
Cancer Cell; 2007 Oct; 12(4):355-66. PubMed ID: 17936560
[TBL] [Abstract][Full Text] [Related]
10. Escape, or Vanish: Control the Fate of p53 through MDM2-Mediated Ubiquitination.
Wei J; Yang Y; Lu M; Xu L; Liu F; Yuan Z; Bao Q; Jiang Z; Xu X; Guo X; Zhang X; You Q; Sun H
Anticancer Agents Med Chem; 2015; 16(2):174-89. PubMed ID: 26343143
[TBL] [Abstract][Full Text] [Related]
11. Critical contribution of the MDM2 acidic domain to p53 ubiquitination.
Kawai H; Wiederschain D; Yuan ZM
Mol Cell Biol; 2003 Jul; 23(14):4939-47. PubMed ID: 12832479
[TBL] [Abstract][Full Text] [Related]
12. Mutant p53 Sequestration of the MDM2 Acidic Domain Inhibits E3 Ligase Activity.
Yang L; Song T; Cheng Q; Chen L; Chen J
Mol Cell Biol; 2019 Feb; 39(4):. PubMed ID: 30455251
[TBL] [Abstract][Full Text] [Related]
13. Overexpression of Mdm2 and MdmX fusion proteins alters p53 mediated transactivation, ubiquitination, and degradation.
Ghosh M; Huang K; Berberich SJ
Biochemistry; 2003 Mar; 42(8):2291-9. PubMed ID: 12600196
[TBL] [Abstract][Full Text] [Related]
14. Regulation of the Mdm2-p53 pathway by the ubiquitin E3 ligase MARCH7.
Zhao K; Yang Y; Zhang G; Wang C; Wang D; Wu M; Mei Y
EMBO Rep; 2018 Feb; 19(2):305-319. PubMed ID: 29295817
[TBL] [Abstract][Full Text] [Related]
15. Regulation of p53 and MDM2 activity by MTBP.
Brady M; Vlatkovic N; Boyd MT
Mol Cell Biol; 2005 Jan; 25(2):545-53. PubMed ID: 15632057
[TBL] [Abstract][Full Text] [Related]
16. MDMX is essential for the regulation of p53 protein levels in the absence of a functional MDM2 C-terminal tail.
Sanford JD; Yang J; Han J; Tollini LA; Jin A; Zhang Y
BMC Mol Cell Biol; 2021 Sep; 22(1):46. PubMed ID: 34551723
[TBL] [Abstract][Full Text] [Related]
17. Mdm2 Splice isoforms regulate the p53/Mdm2/Mdm4 regulatory circuit via RING domain-mediated ubiquitination of p53 and Mdm4.
Fan C; Wang X
Cell Cycle; 2017 Apr; 16(7):660-664. PubMed ID: 28166445
[TBL] [Abstract][Full Text] [Related]
18. Inhibition of p53 degradation by Mdm2 acetylation.
Wang X; Taplick J; Geva N; Oren M
FEBS Lett; 2004 Mar; 561(1-3):195-201. PubMed ID: 15013777
[TBL] [Abstract][Full Text] [Related]
19. Structural and functional comparison of the RING domains of two p53 E3 ligases, Mdm2 and Pirh2.
Shloush J; Vlassov JE; Engson I; Duan S; Saridakis V; Dhe-Paganon S; Raught B; Sheng Y; Arrowsmith CH
J Biol Chem; 2011 Feb; 286(6):4796-808. PubMed ID: 21084285
[TBL] [Abstract][Full Text] [Related]
20. Dynamics in the p53-Mdm2 ubiquitination pathway.
Brooks CL; Gu W
Cell Cycle; 2004 Jul; 3(7):895-9. PubMed ID: 15254415
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
