These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

325 related articles for article (PubMed ID: 18240216)

  • 1. Heparan sulfate-dependent ERK activation contributes to the overexpression of fibrotic proteins and enhanced contraction by scleroderma fibroblasts.
    Chen Y; Leask A; Abraham DJ; Pala D; Shiwen X; Khan K; Liu S; Carter DE; Wilcox-Adelman S; Goetinck P; Denton CP; Black CM; Pitsillides AA; Sarraf CE; Eastwood M
    Arthritis Rheum; 2008 Feb; 58(2):577-85. PubMed ID: 18240216
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Matrix contraction by dermal fibroblasts requires transforming growth factor-beta/activin-linked kinase 5, heparan sulfate-containing proteoglycans, and MEK/ERK: insights into pathological scarring in chronic fibrotic disease.
    Chen Y; Shi-Wen X; van Beek J; Kennedy L; McLeod M; Renzoni EA; Bou-Gharios G; Wilcox-Adelman S; Goetinck PF; Eastwood M; Black CM; Abraham DJ; Leask A
    Am J Pathol; 2005 Dec; 167(6):1699-711. PubMed ID: 16314481
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Angiotensin II in the lesional skin of systemic sclerosis patients contributes to tissue fibrosis via angiotensin II type 1 receptors.
    Kawaguchi Y; Takagi K; Hara M; Fukasawa C; Sugiura T; Nishimagi E; Harigai M; Kamatani N
    Arthritis Rheum; 2004 Jan; 50(1):216-26. PubMed ID: 14730619
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The transcription factor Fra-2 regulates the production of extracellular matrix in systemic sclerosis.
    Reich N; Maurer B; Akhmetshina A; Venalis P; Dees C; Zerr P; Palumbo K; Zwerina J; Nevskaya T; Gay S; Distler O; Schett G; Distler JH
    Arthritis Rheum; 2010 Jan; 62(1):280-90. PubMed ID: 20039427
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Contribution of activin receptor-like kinase 5 (transforming growth factor beta receptor type I) signaling to the fibrotic phenotype of scleroderma fibroblasts.
    Chen Y; Shi-wen X; Eastwood M; Black CM; Denton CP; Leask A; Abraham DJ
    Arthritis Rheum; 2006 Apr; 54(4):1309-16. PubMed ID: 16575856
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Imatinib mesylate reduces production of extracellular matrix and prevents development of experimental dermal fibrosis.
    Distler JH; Jüngel A; Huber LC; Schulze-Horsel U; Zwerina J; Gay RE; Michel BA; Hauser T; Schett G; Gay S; Distler O
    Arthritis Rheum; 2007 Jan; 56(1):311-22. PubMed ID: 17195235
    [TBL] [Abstract][Full Text] [Related]  

  • 7. An increased transforming growth factor beta receptor type I:type II ratio contributes to elevated collagen protein synthesis that is resistant to inhibition via a kinase-deficient transforming growth factor beta receptor type II in scleroderma.
    Pannu J; Gore-Hyer E; Yamanaka M; Smith EA; Rubinchik S; Dong JY; Jablonska S; Blaszczyk M; Trojanowska M
    Arthritis Rheum; 2004 May; 50(5):1566-77. PubMed ID: 15146427
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Modulation of collagen type I, fibronectin and dermal fibroblast function and activity, in systemic sclerosis by the antioxidant epigallocatechin-3-gallate.
    Dooley A; Shi-Wen X; Aden N; Tranah T; Desai N; Denton CP; Abraham DJ; Bruckdorfer R
    Rheumatology (Oxford); 2010 Nov; 49(11):2024-36. PubMed ID: 20627968
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Monocyte chemoattractant protein 3 as a mediator of fibrosis: Overexpression in systemic sclerosis and the type 1 tight-skin mouse.
    Ong VH; Evans LA; Shiwen X; Fisher IB; Rajkumar V; Abraham DJ; Black CM; Denton CP
    Arthritis Rheum; 2003 Jul; 48(7):1979-91. PubMed ID: 12847692
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Expression and regulation of intracellular SMAD signaling in scleroderma skin fibroblasts.
    Mori Y; Chen SJ; Varga J
    Arthritis Rheum; 2003 Jul; 48(7):1964-78. PubMed ID: 12847691
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Increased levels of transforming growth factor beta receptor type I and up-regulation of matrix gene program: A model of scleroderma.
    Pannu J; Gardner H; Shearstone JR; Smith E; Trojanowska M
    Arthritis Rheum; 2006 Sep; 54(9):3011-21. PubMed ID: 16947635
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Src kinases in systemic sclerosis: central roles in fibroblast activation and in skin fibrosis.
    Skhirtladze C; Distler O; Dees C; Akhmetshina A; Busch N; Venalis P; Zwerina J; Spriewald B; Pileckyte M; Schett G; Distler JH
    Arthritis Rheum; 2008 May; 58(5):1475-84. PubMed ID: 18438865
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Systemic sclerosis Th2 cells inhibit collagen production by dermal fibroblasts via membrane-associated tumor necrosis factor alpha.
    Chizzolini C; Parel Y; De Luca C; Tyndall A; Akesson A; Scheja A; Dayer JM
    Arthritis Rheum; 2003 Sep; 48(9):2593-604. PubMed ID: 13130479
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Hypoxia-induced increase in the production of extracellular matrix proteins in systemic sclerosis.
    Distler JH; Jüngel A; Pileckyte M; Zwerina J; Michel BA; Gay RE; Kowal-Bielecka O; Matucci-Cerinic M; Schett G; Marti HH; Gay S; Distler O
    Arthritis Rheum; 2007 Dec; 56(12):4203-15. PubMed ID: 18050252
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Expression of osteonectin, decorin, and transforming growth factor-beta 1 genes in fibroblasts cultured from patients with systemic sclerosis and morphea.
    Vuorio T; Kähäri VM; Black C; Vuorio E
    J Rheumatol; 1991 Feb; 18(2):247-51. PubMed ID: 2023219
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Upregulated expression of transforming growth factor-beta receptors in dermal fibroblasts of skin sections from patients with systemic sclerosis.
    Kubo M; Ihn H; Yamane K; Tamaki K
    J Rheumatol; 2002 Dec; 29(12):2558-64. PubMed ID: 12465152
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Fibroblast expression of the coactivator p300 governs the intensity of profibrotic response to transforming growth factor beta.
    Bhattacharyya S; Ghosh AK; Pannu J; Mori Y; Takagawa S; Chen G; Trojanowska M; Gilliam AC; Varga J
    Arthritis Rheum; 2005 Apr; 52(4):1248-58. PubMed ID: 15818659
    [TBL] [Abstract][Full Text] [Related]  

  • 18. CD109 overexpression ameliorates skin fibrosis in a mouse model of bleomycin-induced scleroderma.
    Vorstenbosch J; Al-Ajmi H; Winocour S; Trzeciak A; Lessard L; Philip A
    Arthritis Rheum; 2013 May; 65(5):1378-83. PubMed ID: 23436317
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Enhanced expression of ephrins and thrombospondins in the dermis of patients with early diffuse systemic sclerosis: potential contribution to perturbed angiogenesis and fibrosis.
    Avouac J; Clemessy M; Distler JH; Gasc JM; Ruiz B; Vacher-Lavenu MC; Wipff J; Kahan A; Boileau C; Corvol P; Allanore Y
    Rheumatology (Oxford); 2011 Aug; 50(8):1494-504. PubMed ID: 21454305
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Impaired IL-17 signaling pathway contributes to the increased collagen expression in scleroderma fibroblasts.
    Nakashima T; Jinnin M; Yamane K; Honda N; Kajihara I; Makino T; Masuguchi S; Fukushima S; Okamoto Y; Hasegawa M; Fujimoto M; Ihn H
    J Immunol; 2012 Apr; 188(8):3573-83. PubMed ID: 22403442
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 17.