These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

180 related articles for article (PubMed ID: 18242046)

  • 1. Identification of the receptor-binding sites in the carboxyl-terminal half of the heavy chain of botulinum neurotoxin types C and D.
    Tsukamoto K; Kozai Y; Ihara H; Kohda T; Mukamoto M; Tsuji T; Kozaki S
    Microb Pathog; 2008 Jun; 44(6):484-93. PubMed ID: 18242046
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Differential contribution of the residues in C-terminal half of the heavy chain of botulinum neurotoxin type B to its binding to the ganglioside GT1b and the synaptotagmin 2/GT1b complex.
    Kohda T; Ihara H; Seto Y; Tsutsuki H; Mukamoto M; Kozaki S
    Microb Pathog; 2007; 42(2-3):72-9. PubMed ID: 17188834
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Binding of Clostridium botulinum type C and D neurotoxins to ganglioside and phospholipid. Novel insights into the receptor for clostridial neurotoxins.
    Tsukamoto K; Kohda T; Mukamoto M; Takeuchi K; Ihara H; Saito M; Kozaki S
    J Biol Chem; 2005 Oct; 280(42):35164-71. PubMed ID: 16115873
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Location of the synaptosome-binding regions on botulinum neurotoxin B.
    Dolimbek BZ; Steward LE; Aoki KR; Atassi MZ
    Biochemistry; 2012 Jan; 51(1):316-28. PubMed ID: 22146011
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Double receptor anchorage of botulinum neurotoxins accounts for their exquisite neurospecificity.
    Rummel A
    Curr Top Microbiol Immunol; 2013; 364():61-90. PubMed ID: 23239349
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Ganglioside GT1b as a complementary receptor component for Clostridium botulinum neurotoxins.
    Kozaki S; Kamata Y; Watarai S; Nishiki T; Mochida S
    Microb Pathog; 1998 Aug; 25(2):91-9. PubMed ID: 9712688
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Structure of botulinum neurotoxin type D light chain at 1.65 A resolution: repercussions for VAMP-2 substrate specificity.
    Arndt JW; Chai Q; Christian T; Stevens RC
    Biochemistry; 2006 Mar; 45(10):3255-62. PubMed ID: 16519520
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The C-terminal heavy-chain domain of botulinum neurotoxin a is not the only site that binds neurons, as the N-terminal heavy-chain domain also plays a very active role in toxin-cell binding and interactions.
    Ayyar BV; Aoki KR; Atassi MZ
    Infect Immun; 2015 Apr; 83(4):1465-76. PubMed ID: 25624352
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Exchange of the H(CC) domain mediating double receptor recognition improves the pharmacodynamic properties of botulinum neurotoxin.
    Rummel A; Mahrhold S; Bigalke H; Binz T
    FEBS J; 2011 Dec; 278(23):4506-15. PubMed ID: 21624052
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Sequence of the gene for Clostridium botulinum type B neurotoxin associated with infant botulism, expression of the C-terminal half of heavy chain and its binding activity.
    Ihara H; Kohda T; Morimoto F; Tsukamoto K; Karasawa T; Nakamura S; Mukamoto M; Kozaki S
    Biochim Biophys Acta; 2003 Jan; 1625(1):19-26. PubMed ID: 12527421
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Cloning, high-level expression, single-step purification, and binding activity of His6-tagged recombinant type B botulinum neurotoxin heavy chain transmembrane and binding domain.
    Zhou Y; Singh BR
    Protein Expr Purif; 2004 Mar; 34(1):8-16. PubMed ID: 14766296
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Structural analysis of the catalytic and binding sites of Clostridium botulinum neurotoxin B.
    Swaminathan S; Eswaramoorthy S
    Nat Struct Biol; 2000 Aug; 7(8):693-9. PubMed ID: 10932256
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Botulinum neurotoxin serotype D attacks neurons via two carbohydrate-binding sites in a ganglioside-dependent manner.
    Strotmeier J; Lee K; Völker AK; Mahrhold S; Zong Y; Zeiser J; Zhou J; Pich A; Bigalke H; Binz T; Rummel A; Jin R
    Biochem J; 2010 Oct; 431(2):207-16. PubMed ID: 20704566
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The HCC-domain of botulinum neurotoxins A and B exhibits a singular ganglioside binding site displaying serotype specific carbohydrate interaction.
    Rummel A; Mahrhold S; Bigalke H; Binz T
    Mol Microbiol; 2004 Feb; 51(3):631-43. PubMed ID: 14731268
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Botulinum neurotoxin D-C uses synaptotagmin I and II as receptors, and human synaptotagmin II is not an effective receptor for type B, D-C and G toxins.
    Peng L; Berntsson RP; Tepp WH; Pitkin RM; Johnson EA; Stenmark P; Dong M
    J Cell Sci; 2012 Jul; 125(Pt 13):3233-42. PubMed ID: 22454523
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Molecular characterization of a novel botulinum neurotoxin type H gene.
    Dover N; Barash JR; Hill KK; Xie G; Arnon SS
    J Infect Dis; 2014 Jan; 209(2):192-202. PubMed ID: 24106295
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Crystal structure of the receptor binding domain of the botulinum C-D mosaic neurotoxin reveals potential roles of lysines 1118 and 1136 in membrane interactions.
    Zhang Y; Buchko GW; Qin L; Robinson H; Varnum SM
    Biochem Biophys Res Commun; 2011 Jan; 404(1):407-12. PubMed ID: 21130733
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Unique biological activity of botulinum D/C mosaic neurotoxin in murine species.
    Nakamura K; Kohda T; Shibata Y; Tsukamoto K; Arimitsu H; Hayashi M; Mukamoto M; Sasakawa N; Kozaki S
    Infect Immun; 2012 Aug; 80(8):2886-93. PubMed ID: 22665374
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Minimal essential domains specifying toxicity of the light chains of tetanus toxin and botulinum neurotoxin type A.
    Kurazono H; Mochida S; Binz T; Eisel U; Quanz M; Grebenstein O; Wernars K; Poulain B; Tauc L; Niemann H
    J Biol Chem; 1992 Jul; 267(21):14721-9. PubMed ID: 1634516
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Botulinum neurotoxin serotype C associates with dual ganglioside receptors to facilitate cell entry.
    Karalewitz AP; Fu Z; Baldwin MR; Kim JJ; Barbieri JT
    J Biol Chem; 2012 Nov; 287(48):40806-16. PubMed ID: 23027864
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.