These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

108 related articles for article (PubMed ID: 18247435)

  • 1. Synthesis and biological evaluation of isosteric analogues of FK866, an inhibitor of NAD salvage.
    Galli U; Ercolano E; Carraro L; Blasi Roman CR; Sorba G; Canonico PL; Genazzani AA; Tron GC; Billington RA
    ChemMedChem; 2008 May; 3(5):771-9. PubMed ID: 18247435
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Chemopotentiating effects of a novel NAD biosynthesis inhibitor, FK866, in combination with antineoplastic agents.
    Pogrebniak A; Schemainda I; Azzam K; Pelka-Fleischer R; Nüssler V; Hasmann M
    Eur J Med Res; 2006 Aug; 11(8):313-21. PubMed ID: 17052966
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Design, synthesis and X-ray crystallographic study of NAmPRTase inhibitors as anti-cancer agents.
    You H; Youn HS; Im I; Bae MH; Lee SK; Ko H; Eom SH; Kim YC
    Eur J Med Chem; 2011 Apr; 46(4):1153-64. PubMed ID: 21330015
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Anticancer agent CHS-828 inhibits cellular synthesis of NAD.
    Olesen UH; Christensen MK; Björkling F; Jäättelä M; Jensen PB; Sehested M; Nielsen SJ
    Biochem Biophys Res Commun; 2008 Mar; 367(4):799-804. PubMed ID: 18201551
    [TBL] [Abstract][Full Text] [Related]  

  • 5. A novel potent nicotinamide phosphoribosyltransferase inhibitor synthesized via click chemistry.
    Colombano G; Travelli C; Galli U; Caldarelli A; Chini MG; Canonico PL; Sorba G; Bifulco G; Tron GC; Genazzani AA
    J Med Chem; 2010 Jan; 53(2):616-23. PubMed ID: 19961183
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Anti-proliferation effect of APO866 on C6 glioblastoma cells by inhibiting nicotinamide phosphoribosyltransferase.
    Zhang LY; Liu LY; Qie LL; Ling KN; Xu LH; Wang F; Fang SH; Lu YB; Hu H; Wei EQ; Zhang WP
    Eur J Pharmacol; 2012 Jan; 674(2-3):163-70. PubMed ID: 22119381
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Reciprocal potentiation of the antitumoral activities of FK866, an inhibitor of nicotinamide phosphoribosyltransferase, and etoposide or cisplatin in neuroblastoma cells.
    Travelli C; Drago V; Maldi E; Kaludercic N; Galli U; Boldorini R; Di Lisa F; Tron GC; Canonico PL; Genazzani AA
    J Pharmacol Exp Ther; 2011 Sep; 338(3):829-40. PubMed ID: 21685314
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Metabolic signatures associated with a NAD synthesis inhibitor-induced tumor apoptosis identified by 1H-decoupled-31P magnetic resonance spectroscopy.
    Muruganandham M; Alfieri AA; Matei C; Chen Y; Sukenick G; Schemainda I; Hasmann M; Saltz LB; Koutcher JA
    Clin Cancer Res; 2005 May; 11(9):3503-13. PubMed ID: 15867253
    [TBL] [Abstract][Full Text] [Related]  

  • 9. FK866, a highly specific noncompetitive inhibitor of nicotinamide phosphoribosyltransferase, represents a novel mechanism for induction of tumor cell apoptosis.
    Hasmann M; Schemainda I
    Cancer Res; 2003 Nov; 63(21):7436-42. PubMed ID: 14612543
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Identification of new FK866 analogues with potent anticancer activity against pancreatic cancer.
    Bai JF; Majjigapu SR; Sordat B; Poty S; Vogel P; Elías-Rodríguez P; Moreno-Vargas AJ; Carmona AT; Caffa I; Ghanem M; Khalifa A; Monacelli F; Cea M; Robina I; Gajate C; Mollinedo F; Bellotti A; Nahimana A; Duchosal M; Nencioni A
    Eur J Med Chem; 2022 Sep; 239():114504. PubMed ID: 35724566
    [TBL] [Abstract][Full Text] [Related]  

  • 11. New Analogues of the Nicotinamide Phosphoribosyltransferase Inhibitor FK866 as Potential Anti-Pancreatic Cancer Agents.
    Conforti I; Benzi A; Caffa I; Bruzzone S; Nencioni A; Marra A
    Med Chem; 2024; 20(7):694-708. PubMed ID: 38333979
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Synthesis of antitumour (1H-1,2,3-triazol-4-yl)-4-hydroxycyclohexa-2,5-dien-1-ones by copper-catalysed Huisgen cycloadditions.
    McCarroll AJ; Matthews CS; Wells G; Bradshaw TD; Stevens MF
    Org Biomol Chem; 2010 May; 8(9):2078-84. PubMed ID: 20401384
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Synthesis and biological evaluation of 4beta-[(4-substituted)-1,2,3-triazol-1-yl]podophyllotoxins as potential anticancer agents.
    Reddy PB; Agrawal SK; Singh S; Bhat BA; Saxena AK; Kumar HM; Qazi GN
    Chem Biodivers; 2008 Sep; 5(9):1792-802. PubMed ID: 18816530
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Design, synthesis, and biological testing of 4beta-[(4-substituted)-1,2,3-triazol-1-yl]podophyllotoxin analogues as antitumor agents.
    Reddy PB; Paul DV; Agrawal SK; Saxena AK; Kumar HM; Qazi GN
    Arch Pharm (Weinheim); 2008 Feb; 341(2):126-31. PubMed ID: 18214838
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Molecular basis for the inhibition of human NMPRTase, a novel target for anticancer agents.
    Khan JA; Tao X; Tong L
    Nat Struct Mol Biol; 2006 Jul; 13(7):582-8. PubMed ID: 16783377
    [TBL] [Abstract][Full Text] [Related]  

  • 16. FK866 compromises mitochondrial metabolism and adaptive stress responses in cultured cardiomyocytes.
    Oyarzún AP; Westermeier F; Pennanen C; López-Crisosto C; Parra V; Sotomayor-Flores C; Sánchez G; Pedrozo Z; Troncoso R; Lavandero S
    Biochem Pharmacol; 2015 Nov; 98(1):92-101. PubMed ID: 26297909
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The NAD biosynthesis inhibitor APO866 has potent antitumor activity against hematologic malignancies.
    Nahimana A; Attinger A; Aubry D; Greaney P; Ireson C; Thougaard AV; Tjørnelund J; Dawson KM; Dupuis M; Duchosal MA
    Blood; 2009 Apr; 113(14):3276-86. PubMed ID: 19196867
    [TBL] [Abstract][Full Text] [Related]  

  • 18. D-ring substituted 1,2,3-triazolyl 20-keto pregnenanes as potential anticancer agents: Synthesis and biological evaluation.
    Banday AH; Shameem SA; Gupta BD; Kumar HM
    Steroids; 2010 Dec; 75(12):801-4. PubMed ID: 20206643
    [TBL] [Abstract][Full Text] [Related]  

  • 19. N-Hydroxy-1,2-disubstituted-1H-benzimidazol-5-yl acrylamides as novel histone deacetylase inhibitors: design, synthesis, SAR studies, and in vivo antitumor activity.
    Wang H; Yu N; Song H; Chen D; Zou Y; Deng W; Lye PL; Chang J; Ng M; Sun ET; Sangthongpitag K; Wang X; Wu X; Khng HH; Fang L; Goh SK; Ong WC; Bonday Z; Stünkel W; Poulsen A; Entzeroth M
    Bioorg Med Chem Lett; 2009 Mar; 19(5):1403-8. PubMed ID: 19181524
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The anti-lymphoma activity of APO866, an inhibitor of nicotinamide adenine dinucleotide biosynthesis, is potentialized when used in combination with anti-CD20 antibody.
    Nahimana A; Aubry D; Breton CS; Majjigapu SR; Sordat B; Vogel P; Duchosal MA
    Leuk Lymphoma; 2014 Sep; 55(9):2141-50. PubMed ID: 24283753
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 6.