These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

307 related articles for article (PubMed ID: 18248604)

  • 1. Statins reduce neuronal alpha-synuclein aggregation in in vitro models of Parkinson's disease.
    Bar-On P; Crews L; Koob AO; Mizuno H; Adame A; Spencer B; Masliah E
    J Neurochem; 2008 Jun; 105(5):1656-67. PubMed ID: 18248604
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Lovastatin ameliorates alpha-synuclein accumulation and oxidation in transgenic mouse models of alpha-synucleinopathies.
    Koob AO; Ubhi K; Paulsson JF; Kelly J; Rockenstein E; Mante M; Adame A; Masliah E
    Exp Neurol; 2010 Feb; 221(2):267-74. PubMed ID: 19944097
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Effects of the cholesterol-lowering compound methyl-beta-cyclodextrin in models of alpha-synucleinopathy.
    Bar-On P; Rockenstein E; Adame A; Ho G; Hashimoto M; Masliah E
    J Neurochem; 2006 Aug; 98(4):1032-45. PubMed ID: 16895578
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The contribution of alpha synuclein to neuronal survival and function - Implications for Parkinson's disease.
    Benskey MJ; Perez RG; Manfredsson FP
    J Neurochem; 2016 May; 137(3):331-59. PubMed ID: 26852372
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Synapsin III deficiency hampers α-synuclein aggregation, striatal synaptic damage and nigral cell loss in an AAV-based mouse model of Parkinson's disease.
    Faustini G; Longhena F; Varanita T; Bubacco L; Pizzi M; Missale C; Benfenati F; Björklund A; Spano P; Bellucci A
    Acta Neuropathol; 2018 Oct; 136(4):621-639. PubMed ID: 30046897
    [TBL] [Abstract][Full Text] [Related]  

  • 6. An Overview on the Role of α -Synuclein in Experimental Models of Parkinson's Disease from Pathogenesis to Therapeutics.
    Javed H; Kamal MA; Ojha S
    CNS Neurol Disord Drug Targets; 2016; 15(10):1240-1252. PubMed ID: 27658511
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Lipids: Key Players That Modulate α-Synuclein Toxicity and Neurodegeneration in Parkinson's Disease.
    Mori A; Imai Y; Hattori N
    Int J Mol Sci; 2020 May; 21(9):. PubMed ID: 32392751
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Loss of functional alpha-synuclein: a toxic event in Parkinson's disease?
    Kanaan NM; Manfredsson FP
    J Parkinsons Dis; 2012; 2(4):249-67. PubMed ID: 23938255
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Sequestration of synaptic proteins by alpha-synuclein aggregates leading to neurotoxicity is inhibited by small peptide.
    Choi MG; Kim MJ; Kim DG; Yu R; Jang YN; Oh WJ
    PLoS One; 2018; 13(4):e0195339. PubMed ID: 29608598
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Co-aggregation of pro-inflammatory S100A9 with α-synuclein in Parkinson's disease: ex vivo and in vitro studies.
    Horvath I; Iashchishyn IA; Moskalenko RA; Wang C; Wärmländer SKTS; Wallin C; Gräslund A; Kovacs GG; Morozova-Roche LA
    J Neuroinflammation; 2018 Jun; 15(1):172. PubMed ID: 29866153
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Activation of β-Glucocerebrosidase Reduces Pathological α-Synuclein and Restores Lysosomal Function in Parkinson's Patient Midbrain Neurons.
    Mazzulli JR; Zunke F; Tsunemi T; Toker NJ; Jeon S; Burbulla LF; Patnaik S; Sidransky E; Marugan JJ; Sue CM; Krainc D
    J Neurosci; 2016 Jul; 36(29):7693-706. PubMed ID: 27445146
    [TBL] [Abstract][Full Text] [Related]  

  • 12. What can trigger the onset of Parkinson's disease - A modeling study based on a compartmental model of α-synuclein transport and aggregation in neurons.
    Kuznetsov IA; Kuznetsov AV
    Math Biosci; 2016 Aug; 278():22-9. PubMed ID: 27211070
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The process of Lewy body formation, rather than simply α-synuclein fibrillization, is one of the major drivers of neurodegeneration.
    Mahul-Mellier AL; Burtscher J; Maharjan N; Weerens L; Croisier M; Kuttler F; Leleu M; Knott GW; Lashuel HA
    Proc Natl Acad Sci U S A; 2020 Mar; 117(9):4971-4982. PubMed ID: 32075919
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Lycorine, a natural alkaloid, promotes the degradation of alpha-synuclein via PKA-mediated UPS activation in transgenic Parkinson's disease models.
    Zhu Q; Zhuang XX; Chen JY; Yuan NN; Chen Y; Cai CZ; Tan JQ; Su HX; Lu JH
    Phytomedicine; 2021 Jul; 87():153578. PubMed ID: 34038839
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Alteration of Structure and Aggregation of α-Synuclein by Familial Parkinson's Disease Associated Mutations.
    Sahay S; Ghosh D; Singh PK; Maji SK
    Curr Protein Pept Sci; 2017; 18(7):656-676. PubMed ID: 26972727
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Inhibition of FK506 binding proteins reduces alpha-synuclein aggregation and Parkinson's disease-like pathology.
    Gerard M; Deleersnijder A; Daniëls V; Schreurs S; Munck S; Reumers V; Pottel H; Engelborghs Y; Van den Haute C; Taymans JM; Debyser Z; Baekelandt V
    J Neurosci; 2010 Feb; 30(7):2454-63. PubMed ID: 20164329
    [TBL] [Abstract][Full Text] [Related]  

  • 17. α-Synuclein aggregation and transmission in Parkinson's disease: a link to mitochondria and lysosome.
    Wang R; Sun H; Ren H; Wang G
    Sci China Life Sci; 2020 Dec; 63(12):1850-1859. PubMed ID: 32681494
    [TBL] [Abstract][Full Text] [Related]  

  • 18. LRRK2 modifies α-syn pathology and spread in mouse models and human neurons.
    Bieri G; Brahic M; Bousset L; Couthouis J; Kramer NJ; Ma R; Nakayama L; Monbureau M; Defensor E; Schüle B; Shamloo M; Melki R; Gitler AD
    Acta Neuropathol; 2019 Jun; 137(6):961-980. PubMed ID: 30927072
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Lipid metabolism alterations in the neuronal response to A53T α-synuclein and Fe-induced injury.
    Sánchez Campos S; Alza NP; Salvador GA
    Arch Biochem Biophys; 2018 Oct; 655():43-54. PubMed ID: 30098984
    [TBL] [Abstract][Full Text] [Related]  

  • 20. T cell infiltration and upregulation of MHCII in microglia leads to accelerated neuronal loss in an α-synuclein rat model of Parkinson's disease.
    Subbarayan MS; Hudson C; Moss LD; Nash KR; Bickford PC
    J Neuroinflammation; 2020 Aug; 17(1):242. PubMed ID: 32799878
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 16.