BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

561 related articles for article (PubMed ID: 18248870)

  • 1. Chimeric mice with humanized liver.
    Katoh M; Tateno C; Yoshizato K; Yokoi T
    Toxicology; 2008 Apr; 246(1):9-17. PubMed ID: 18248870
    [TBL] [Abstract][Full Text] [Related]  

  • 2. In vivo drug metabolism model for human cytochrome P450 enzyme using chimeric mice with humanized liver.
    Katoh M; Sawada T; Soeno Y; Nakajima M; Tateno C; Yoshizato K; Yokoi T
    J Pharm Sci; 2007 Feb; 96(2):428-37. PubMed ID: 17051594
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Application of chimeric mice with humanized liver for predictive ADME.
    Katoh M; Yokoi T
    Drug Metab Rev; 2007; 39(1):145-57. PubMed ID: 17364883
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Development of Murine Cyp3a Knockout Chimeric Mice with Humanized Liver.
    Kato K; Ohbuchi M; Hamamura S; Ohshita H; Kazuki Y; Oshimura M; Sato K; Nakada N; Kawamura A; Usui T; Kamimura H; Tateno C
    Drug Metab Dispos; 2015 Aug; 43(8):1208-17. PubMed ID: 25979261
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Current status of prediction of drug disposition and toxicity in humans using chimeric mice with humanized liver.
    Kitamura S; Sugihara K
    Xenobiotica; 2014 Jan; 44(2):123-34. PubMed ID: 24329499
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Humanization of excretory pathway in chimeric mice with humanized liver.
    Okumura H; Katoh M; Sawada T; Nakajima M; Soeno Y; Yabuuchi H; Ikeda T; Tateno C; Yoshizato K; Yokoi T
    Toxicol Sci; 2007 Jun; 97(2):533-8. PubMed ID: 17341479
    [TBL] [Abstract][Full Text] [Related]  

  • 7. In vitro evaluation of cytochrome P450 and glucuronidation activities in hepatocytes isolated from liver-humanized mice.
    Yamasaki C; Kataoka M; Kato Y; Kakuni M; Usuda S; Ohzone Y; Matsuda S; Adachi Y; Ninomiya S; Itamoto T; Asahara T; Yoshizato K; Tateno C
    Drug Metab Pharmacokinet; 2010; 25(6):539-50. PubMed ID: 20930422
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Prediction of in vivo hepatic clearance and half-life of drug candidates in human using chimeric mice with humanized liver.
    Sanoh S; Horiguchi A; Sugihara K; Kotake Y; Tayama Y; Ohshita H; Tateno C; Horie T; Kitamura S; Ohta S
    Drug Metab Dispos; 2012 Feb; 40(2):322-8. PubMed ID: 22048522
    [TBL] [Abstract][Full Text] [Related]  

  • 9. CYP2C9-catalyzed metabolism of S-warfarin to 7-hydroxywarfarin in vivo and in vitro in chimeric mice with humanized liver.
    Inoue T; Nitta K; Sugihara K; Horie T; Kitamura S; Ohta S
    Drug Metab Dispos; 2008 Dec; 36(12):2429-33. PubMed ID: 18784266
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Near completely humanized liver in mice shows human-type metabolic responses to drugs.
    Tateno C; Yoshizane Y; Saito N; Kataoka M; Utoh R; Yamasaki C; Tachibana A; Soeno Y; Asahina K; Hino H; Asahara T; Yokoi T; Furukawa T; Yoshizato K
    Am J Pathol; 2004 Sep; 165(3):901-12. PubMed ID: 15331414
    [TBL] [Abstract][Full Text] [Related]  

  • 11. In vivo induction of human cytochrome P450 3A4 by rifabutin in chimeric mice with humanized liver.
    Katoh M; Watanabe M; Tabata T; Sato Y; Nakajima M; Nishimura M; Naito S; Tateno C; Iwasaki K; Yoshizato K; Yokoi T
    Xenobiotica; 2005 Sep; 35(9):863-75. PubMed ID: 16308281
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Human cytochrome P450 isozymes in metabolism and health effects of gasoline ethers.
    Hong JY; Wang YY; Mohr SN; Bondoc FY; Deng C
    Res Rep Health Eff Inst; 2001 May; (102):7-27; discussion 95-109. PubMed ID: 11504148
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Chimeric mice transplanted with human hepatocytes as a model for prediction of human drug metabolism and pharmacokinetics.
    Sanoh S; Ohta S
    Biopharm Drug Dispos; 2014 Mar; 35(2):71-86. PubMed ID: 24114658
    [TBL] [Abstract][Full Text] [Related]  

  • 14. In vivo induction of human cytochrome P450 enzymes expressed in chimeric mice with humanized liver.
    Katoh M; Matsui T; Nakajima M; Tateno C; Soeno Y; Horie T; Iwasaki K; Yoshizato K; Yokoi T
    Drug Metab Dispos; 2005 Jun; 33(6):754-63. PubMed ID: 15769886
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Assessment of chimeric mice with humanized liver as a tool for predicting circulating human metabolites.
    Kamimura H; Nakada N; Suzuki K; Mera A; Souda K; Murakami Y; Tanaka K; Iwatsubo T; Kawamura A; Usui T
    Drug Metab Pharmacokinet; 2010; 25(3):223-35. PubMed ID: 20610881
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Chimeric mice with humanized liver: tools for the study of drug metabolism, excretion, and toxicity.
    Strom SC; Davila J; Grompe M
    Methods Mol Biol; 2010; 640():491-509. PubMed ID: 20645070
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Effect of hepatitis C virus infection on the mRNA expression of drug transporters and cytochrome p450 enzymes in chimeric mice with humanized liver.
    Kikuchi R; McCown M; Olson P; Tateno C; Morikawa Y; Katoh Y; Bourdet DL; Monshouwer M; Fretland AJ
    Drug Metab Dispos; 2010 Nov; 38(11):1954-61. PubMed ID: 20693416
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Expression of human cytochromes P450 in chimeric mice with humanized liver.
    Katoh M; Matsui T; Nakajima M; Tateno C; Kataoka M; Soeno Y; Horie T; Iwasaki K; Yoshizato K; Yokoi T
    Drug Metab Dispos; 2004 Dec; 32(12):1402-10. PubMed ID: 15383493
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Selective effect of liver disease on the activities of specific metabolizing enzymes: investigation of cytochromes P450 2C19 and 2D6.
    Adedoyin A; Arns PA; Richards WO; Wilkinson GR; Branch RA
    Clin Pharmacol Ther; 1998 Jul; 64(1):8-17. PubMed ID: 9695714
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Human hepatic stem cells transplanted into a fulminant hepatic failure Alb-TRECK/SCID mouse model exhibit liver reconstitution and drug metabolism capabilities.
    Zhang RR; Zheng YW; Li B; Tsuchida T; Ueno Y; Nie YZ; Taniguchi H
    Stem Cell Res Ther; 2015 Mar; 6(1):49. PubMed ID: 25889844
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 29.