BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

195 related articles for article (PubMed ID: 18250420)

  • 1. IL-12 is required for anti-OX40-mediated CD4 T cell survival.
    Ruby CE; Montler R; Zheng R; Shu S; Weinberg AD
    J Immunol; 2008 Feb; 180(4):2140-8. PubMed ID: 18250420
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Activated STAT4 has an essential role in Th1 differentiation and proliferation that is independent of its role in the maintenance of IL-12R beta 2 chain expression and signaling.
    Nishikomori R; Usui T; Wu CY; Morinobu A; O'Shea JJ; Strober W
    J Immunol; 2002 Oct; 169(8):4388-98. PubMed ID: 12370372
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Combined targeting of costimulatory (OX40) and coinhibitory (CTLA-4) pathways elicits potent effector T cells capable of driving robust antitumor immunity.
    Redmond WL; Linch SN; Kasiewicz MJ
    Cancer Immunol Res; 2014 Feb; 2(2):142-53. PubMed ID: 24778278
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The OX40 costimulatory receptor determines the development of CD4 memory by regulating primary clonal expansion.
    Gramaglia I; Jember A; Pippig SD; Weinberg AD; Killeen N; Croft M
    J Immunol; 2000 Sep; 165(6):3043-50. PubMed ID: 10975814
    [TBL] [Abstract][Full Text] [Related]  

  • 5. OX40-mediated differentiation to effector function requires IL-2 receptor signaling but not CD28, CD40, IL-12Rbeta2, or T-bet.
    Williams CA; Murray SE; Weinberg AD; Parker DC
    J Immunol; 2007 Jun; 178(12):7694-702. PubMed ID: 17548606
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Combination OX40 agonism/CTLA-4 blockade with HER2 vaccination reverses T-cell anergy and promotes survival in tumor-bearing mice.
    Linch SN; Kasiewicz MJ; McNamara MJ; Hilgart-Martiszus IF; Farhad M; Redmond WL
    Proc Natl Acad Sci U S A; 2016 Jan; 113(3):E319-27. PubMed ID: 26729864
    [TBL] [Abstract][Full Text] [Related]  

  • 7. OX40-OX40 ligand interaction through T cell-T cell contact contributes to CD4 T cell longevity.
    Soroosh P; Ine S; Sugamura K; Ishii N
    J Immunol; 2006 May; 176(10):5975-87. PubMed ID: 16670306
    [TBL] [Abstract][Full Text] [Related]  

  • 8. OX40-enhanced tumor rejection and effector T cell differentiation decreases with age.
    Ruby CE; Weinberg AD
    J Immunol; 2009 Feb; 182(3):1481-9. PubMed ID: 19155495
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Ligation of the OX40 co-stimulatory receptor reverses self-Ag and tumor-induced CD8 T-cell anergy in vivo.
    Redmond WL; Gough MJ; Weinberg AD
    Eur J Immunol; 2009 Aug; 39(8):2184-94. PubMed ID: 19672905
    [TBL] [Abstract][Full Text] [Related]  

  • 10. OX40 and IL-7 play synergistic roles in the homeostatic proliferation of effector memory CD4⁺ T cells.
    Yamaki S; Ine S; Kawabe T; Okuyama Y; Suzuki N; Soroosh P; Mousavi SF; Nagashima H; Sun SL; So T; Sasaki T; Harigae H; Sugamura K; Kudo H; Wada M; Nio M; Ishii N
    Eur J Immunol; 2014 Oct; 44(10):3015-25. PubMed ID: 25103720
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Dual anti-OX40/IL-2 therapy augments tumor immunotherapy via IL-2R-mediated regulation of OX40 expression.
    Redmond WL; Triplett T; Floyd K; Weinberg AD
    PLoS One; 2012; 7(4):e34467. PubMed ID: 22496812
    [TBL] [Abstract][Full Text] [Related]  

  • 12. 4-1BB ligand induces cell division, sustains survival, and enhances effector function of CD4 and CD8 T cells with similar efficacy.
    Cannons JL; Lau P; Ghumman B; DeBenedette MA; Yagita H; Okumura K; Watts TH
    J Immunol; 2001 Aug; 167(3):1313-24. PubMed ID: 11466348
    [TBL] [Abstract][Full Text] [Related]  

  • 13. A diametric role for OX40 in the response of effector/memory CD4+ T cells and regulatory T cells to alloantigen.
    Kinnear G; Wood KJ; Fallah-Arani F; Jones ND
    J Immunol; 2013 Aug; 191(3):1465-75. PubMed ID: 23817421
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Defects in the acquisition of CD8 T cell effector function after priming with tumor or soluble antigen can be overcome by the addition of an OX40 agonist.
    Redmond WL; Gough MJ; Charbonneau B; Ratliff TL; Weinberg AD
    J Immunol; 2007 Dec; 179(11):7244-53. PubMed ID: 18025166
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Differential requirements for OX40 signals on generation of effector and central memory CD4+ T cells.
    Soroosh P; Ine S; Sugamura K; Ishii N
    J Immunol; 2007 Oct; 179(8):5014-23. PubMed ID: 17911586
    [TBL] [Abstract][Full Text] [Related]  

  • 16. OX40 signals during priming on dendritic cells inhibit CD4 T cell proliferation: IL-4 switches off OX40 signals enabling rapid proliferation of Th2 effectors.
    Kim MY; Bekiaris V; McConnell FM; Gaspal FM; Raykundalia C; Lane PJ
    J Immunol; 2005 Feb; 174(3):1433-7. PubMed ID: 15661901
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The survival of memory CD4+ T cells within the gut lamina propria requires OX40 and CD30 signals.
    Withers DR; Jaensson E; Gaspal F; McConnell FM; Eksteen B; Anderson G; Agace WW; Lane PJL
    J Immunol; 2009 Oct; 183(8):5079-84. PubMed ID: 19786532
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Danger and OX40 receptor signaling synergize to enhance memory T cell survival by inhibiting peripheral deletion.
    Maxwell JR; Weinberg A; Prell RA; Vella AT
    J Immunol; 2000 Jan; 164(1):107-12. PubMed ID: 10605000
    [TBL] [Abstract][Full Text] [Related]  

  • 19. High levels of costimulatory receptors OX40 and 4-1BB characterize CD4+CD28null T cells in patients with acute coronary syndrome.
    Dumitriu IE; Baruah P; Finlayson CJ; Loftus IM; Antunes RF; Lim P; Bunce N; Kaski JC
    Circ Res; 2012 Mar; 110(6):857-69. PubMed ID: 22282196
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Activation of NF-kappaB1 by OX40 contributes to antigen-driven T cell expansion and survival.
    Song J; So T; Croft M
    J Immunol; 2008 Jun; 180(11):7240-8. PubMed ID: 18490723
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.