BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

352 related articles for article (PubMed ID: 18250621)

  • 1. The RecQ helicase WRN is required for normal replication fork progression after DNA damage or replication fork arrest.
    Sidorova JM; Li N; Folch A; Monnat RJ
    Cell Cycle; 2008 Mar; 7(6):796-807. PubMed ID: 18250621
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Functional role of the Werner syndrome RecQ helicase in human fibroblasts.
    Dhillon KK; Sidorova J; Saintigny Y; Poot M; Gollahon K; Rabinovitch PS; Monnat RJ
    Aging Cell; 2007 Feb; 6(1):53-61. PubMed ID: 17266675
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Distinct functions of human RECQ helicases WRN and BLM in replication fork recovery and progression after hydroxyurea-induced stalling.
    Sidorova JM; Kehrli K; Mao F; Monnat R
    DNA Repair (Amst); 2013 Feb; 12(2):128-39. PubMed ID: 23253856
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The Werner syndrome protein: linking the replication checkpoint response to genome stability.
    Pichierri P; Ammazzalorso F; Bignami M; Franchitto A
    Aging (Albany NY); 2011 Mar; 3(3):311-8. PubMed ID: 21389352
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Molecular cooperation between the Werner syndrome protein and replication protein A in relation to replication fork blockage.
    Machwe A; Lozada E; Wold MS; Li GM; Orren DK
    J Biol Chem; 2011 Feb; 286(5):3497-508. PubMed ID: 21107010
    [TBL] [Abstract][Full Text] [Related]  

  • 6. ATR and ATM differently regulate WRN to prevent DSBs at stalled replication forks and promote replication fork recovery.
    Ammazzalorso F; Pirzio LM; Bignami M; Franchitto A; Pichierri P
    EMBO J; 2010 Sep; 29(18):3156-69. PubMed ID: 20802463
    [TBL] [Abstract][Full Text] [Related]  

  • 7. WRN helicase regulates the ATR-CHK1-induced S-phase checkpoint pathway in response to topoisomerase-I-DNA covalent complexes.
    Patro BS; Frøhlich R; Bohr VA; Stevnsner T
    J Cell Sci; 2011 Dec; 124(Pt 23):3967-79. PubMed ID: 22159421
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Werner's syndrome protein is phosphorylated in an ATR/ATM-dependent manner following replication arrest and DNA damage induced during the S phase of the cell cycle.
    Pichierri P; Rosselli F; Franchitto A
    Oncogene; 2003 Mar; 22(10):1491-500. PubMed ID: 12629512
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Replication fork regression in vitro by the Werner syndrome protein (WRN): holliday junction formation, the effect of leading arm structure and a potential role for WRN exonuclease activity.
    Machwe A; Xiao L; Lloyd RG; Bolt E; Orren DK
    Nucleic Acids Res; 2007; 35(17):5729-47. PubMed ID: 17717003
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Werner syndrome protein and the MRE11 complex are involved in a common pathway of replication fork recovery.
    Franchitto A; Pichierri P
    Cell Cycle; 2004 Oct; 3(10):1331-9. PubMed ID: 15467456
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The Werner syndrome protein functions in repair of Cr(VI)-induced replication-associated DNA damage.
    Liu FJ; Barchowsky A; Opresko PL
    Toxicol Sci; 2009 Aug; 110(2):307-18. PubMed ID: 19487340
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The human WRN and BLM RecQ helicases differentially regulate cell proliferation and survival after chemotherapeutic DNA damage.
    Mao FJ; Sidorova JM; Lauper JM; Emond MJ; Monnat RJ
    Cancer Res; 2010 Aug; 70(16):6548-55. PubMed ID: 20663905
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The RAD9-RAD1-HUS1 (9.1.1) complex interacts with WRN and is crucial to regulate its response to replication fork stalling.
    Pichierri P; Nicolai S; Cignolo L; Bignami M; Franchitto A
    Oncogene; 2012 Jun; 31(23):2809-23. PubMed ID: 22002307
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The Werner and Bloom syndrome proteins catalyze regression of a model replication fork.
    Machwe A; Xiao L; Groden J; Orren DK
    Biochemistry; 2006 Nov; 45(47):13939-46. PubMed ID: 17115688
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Class I Histone Deacetylase HDAC1 and WRN RECQ Helicase Contribute Additively to Protect Replication Forks upon Hydroxyurea-induced Arrest.
    Kehrli K; Phelps M; Lazarchuk P; Chen E; Monnat R; Sidorova JM
    J Biol Chem; 2016 Nov; 291(47):24487-24503. PubMed ID: 27672210
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Inhibition of helicase activity by a small molecule impairs Werner syndrome helicase (WRN) function in the cellular response to DNA damage or replication stress.
    Aggarwal M; Sommers JA; Shoemaker RH; Brosh RM
    Proc Natl Acad Sci U S A; 2011 Jan; 108(4):1525-30. PubMed ID: 21220316
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Replication stress induced site-specific phosphorylation targets WRN to the ubiquitin-proteasome pathway.
    Su F; Bhattacharya S; Abdisalaam S; Mukherjee S; Yajima H; Yang Y; Mishra R; Srinivasan K; Ghose S; Chen DJ; Yannone SM; Asaithamby A
    Oncotarget; 2016 Jan; 7(1):46-65. PubMed ID: 26695548
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The Werner syndrome protein binds replication fork and holliday junction DNAs as an oligomer.
    Compton SA; Tolun G; Kamath-Loeb AS; Loeb LA; Griffith JD
    J Biol Chem; 2008 Sep; 283(36):24478-83. PubMed ID: 18596042
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Roles of the Werner syndrome RecQ helicase in DNA replication.
    Sidorova JM
    DNA Repair (Amst); 2008 Nov; 7(11):1776-86. PubMed ID: 18722555
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Checkpoint-dependent and independent roles of the Werner syndrome protein in preserving genome integrity in response to mild replication stress.
    Basile G; Leuzzi G; Pichierri P; Franchitto A
    Nucleic Acids Res; 2014 Nov; 42(20):12628-39. PubMed ID: 25352544
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 18.