BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

389 related articles for article (PubMed ID: 18255062)

  • 1. Inhibition of endoplasmic reticulum stress counteracts neuronal cell death and protein aggregation caused by N-terminal mutant huntingtin proteins.
    Reijonen S; Putkonen N; Nørremølle A; Lindholm D; Korhonen L
    Exp Cell Res; 2008 Mar; 314(5):950-60. PubMed ID: 18255062
    [TBL] [Abstract][Full Text] [Related]  

  • 2. GRP78 counteracts cell death and protein aggregation caused by mutant huntingtin proteins.
    Jiang Y; Lv H; Liao M; Xu X; Huang S; Tan H; Peng T; Zhang Y; Li H
    Neurosci Lett; 2012 May; 516(2):182-7. PubMed ID: 22490889
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Herp Promotes Degradation of Mutant Huntingtin: Involvement of the Proteasome and Molecular Chaperones.
    Luo H; Cao L; Liang X; Du A; Peng T; Li H
    Mol Neurobiol; 2018 Oct; 55(10):7652-7668. PubMed ID: 29430620
    [TBL] [Abstract][Full Text] [Related]  

  • 4. IRE1 plays an essential role in ER stress-mediated aggregation of mutant huntingtin via the inhibition of autophagy flux.
    Lee H; Noh JY; Oh Y; Kim Y; Chang JW; Chung CW; Lee ST; Kim M; Ryu H; Jung YK
    Hum Mol Genet; 2012 Jan; 21(1):101-14. PubMed ID: 21954231
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Endoplasmic reticulum stress modulates nicotine-induced extracellular matrix degradation in human periodontal ligament cells.
    Lee SI; Kang KL; Shin SI; Herr Y; Lee YM; Kim EC
    J Periodontal Res; 2012 Jun; 47(3):299-308. PubMed ID: 22489671
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Oxidative stress promotes mutant huntingtin aggregation and mutant huntingtin-dependent cell death by mimicking proteasomal malfunction.
    Goswami A; Dikshit P; Mishra A; Mulherkar S; Nukina N; Jana NR
    Biochem Biophys Res Commun; 2006 Mar; 342(1):184-90. PubMed ID: 16472774
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Endoplasmic Reticulum Stress Plays a Key Role in Rotenone-Induced Apoptotic Death of Neurons.
    Goswami P; Gupta S; Biswas J; Joshi N; Swarnkar S; Nath C; Singh S
    Mol Neurobiol; 2016 Jan; 53(1):285-298. PubMed ID: 25428620
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Changes in BiP availability reveal hypersensitivity to acute endoplasmic reticulum stress in cells expressing mutant huntingtin.
    Lajoie P; Snapp EL
    J Cell Sci; 2011 Oct; 124(Pt 19):3332-43. PubMed ID: 21896647
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Reversal of a full-length mutant huntingtin neuronal cell phenotype by chemical inhibitors of polyglutamine-mediated aggregation.
    Wang J; Gines S; MacDonald ME; Gusella JF
    BMC Neurosci; 2005 Jan; 6():1. PubMed ID: 15649316
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Transient receptor potential vanilloid 1 agonists cause endoplasmic reticulum stress and cell death in human lung cells.
    Thomas KC; Sabnis AS; Johansen ME; Lanza DL; Moos PJ; Yost GS; Reilly CA
    J Pharmacol Exp Ther; 2007 Jun; 321(3):830-8. PubMed ID: 17332266
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Effects of salubrinal on cadmium-induced apoptosis in HK-2 human renal proximal tubular cells.
    Komoike Y; Inamura H; Matsuoka M
    Arch Toxicol; 2012 Jan; 86(1):37-44. PubMed ID: 21809093
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Arsenic induces reactive oxygen species-caused neuronal cell apoptosis through JNK/ERK-mediated mitochondria-dependent and GRP 78/CHOP-regulated pathways.
    Lu TH; Tseng TJ; Su CC; Tang FC; Yen CC; Liu YY; Yang CY; Wu CC; Chen KL; Hung DZ; Chen YW
    Toxicol Lett; 2014 Jan; 224(1):130-40. PubMed ID: 24157283
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Rosiglitazone activation of PPARγ-dependent signaling is neuroprotective in mutant huntingtin expressing cells.
    Chiang MC; Cheng YC; Nicol CJ; Lin KH; Yen CH; Chen SJ; Huang RN
    Exp Cell Res; 2015 Nov; 338(2):183-93. PubMed ID: 26362846
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Aggregation in Huntington's disease: insights through modelling.
    Cajavec B; Bernard S; Herzel H
    Genome Inform; 2005; 16(1):262-71. PubMed ID: 16362929
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Chaperone suppression of cellular toxicity of huntingtin is independent of polyglutamine aggregation.
    Zhou H; Li SH; Li XJ
    J Biol Chem; 2001 Dec; 276(51):48417-24. PubMed ID: 11606565
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Heat shock protein 27 prevents cellular polyglutamine toxicity and suppresses the increase of reactive oxygen species caused by huntingtin.
    Wyttenbach A; Sauvageot O; Carmichael J; Diaz-Latoud C; Arrigo AP; Rubinsztein DC
    Hum Mol Genet; 2002 May; 11(9):1137-51. PubMed ID: 11978772
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Sigma-1 receptor is involved in degradation of intranuclear inclusions in a cellular model of Huntington's disease.
    Miki Y; Tanji K; Mori F; Wakabayashi K
    Neurobiol Dis; 2015 Feb; 74():25-31. PubMed ID: 25449906
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Enhanced signaling downstream of ribonucleic Acid-activated protein kinase-like endoplasmic reticulum kinase potentiates lipotoxic endoplasmic reticulum stress in human islets.
    Ladrière L; Igoillo-Esteve M; Cunha DA; Brion JP; Bugliani M; Marchetti P; Eizirik DL; Cnop M
    J Clin Endocrinol Metab; 2010 Mar; 95(3):1442-9. PubMed ID: 20080856
    [TBL] [Abstract][Full Text] [Related]  

  • 19. ENC1 Modulates the Aggregation and Neurotoxicity of Mutant Huntingtin Through p62 Under ER Stress.
    Lee H; Ahn HH; Lee W; Oh Y; Choi H; Shim SM; Shin J; Jung YK
    Mol Neurobiol; 2016 Dec; 53(10):6620-6634. PubMed ID: 26637326
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Wild type Huntingtin reduces the cellular toxicity of mutant Huntingtin in mammalian cell models of Huntington's disease.
    Ho LW; Brown R; Maxwell M; Wyttenbach A; Rubinsztein DC
    J Med Genet; 2001 Jul; 38(7):450-2. PubMed ID: 11432963
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 20.