These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

196 related articles for article (PubMed ID: 18258846)

  • 1. Integrin alpha1beta1 regulates matrix metalloproteinases via P38 mitogen-activated protein kinase in mesangial cells: implications for Alport syndrome.
    Cosgrove D; Meehan DT; Delimont D; Pozzi A; Chen X; Rodgers KD; Tempero RM; Zallocchi M; Rao VH
    Am J Pathol; 2008 Mar; 172(3):761-73. PubMed ID: 18258846
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Upregulated expression of integrin α1 in mesangial cells and integrin α3 and vimentin in podocytes of Col4a3-null (Alport) mice.
    Steenhard BM; Vanacore R; Friedman D; Zelenchuk A; Stroganova L; Isom K; St John PL; Hudson BG; Abrahamson DR
    PLoS One; 2012; 7(12):e50745. PubMed ID: 23236390
    [TBL] [Abstract][Full Text] [Related]  

  • 3. α1β1 integrin/Rac1-dependent mesangial invasion of glomerular capillaries in Alport syndrome.
    Zallocchi M; Johnson BM; Meehan DT; Delimont D; Cosgrove D
    Am J Pathol; 2013 Oct; 183(4):1269-1280. PubMed ID: 23911822
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Glomerular basement membrane deposition of collagen α1(III) in Alport glomeruli by mesangial filopodia injures podocytes via aberrant signaling through DDR1 and integrin α2β1.
    Madison J; Wilhelm K; Meehan DT; Delimont D; Samuelson G; Cosgrove D
    J Pathol; 2022 Sep; 258(1):26-37. PubMed ID: 35607980
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Laminin α2-mediated focal adhesion kinase activation triggers Alport glomerular pathogenesis.
    Delimont D; Dufek BM; Meehan DT; Zallocchi M; Gratton MA; Phillips G; Cosgrove D
    PLoS One; 2014; 9(6):e99083. PubMed ID: 24915008
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Integrin alpha1beta1 and transforming growth factor-beta1 play distinct roles in alport glomerular pathogenesis and serve as dual targets for metabolic therapy.
    Cosgrove D; Rodgers K; Meehan D; Miller C; Bovard K; Gilroy A; Gardner H; Kotelianski V; Gotwals P; Amatucci A; Kalluri R
    Am J Pathol; 2000 Nov; 157(5):1649-59. PubMed ID: 11073824
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Glomerular injury is exacerbated in diabetic integrin alpha1-null mice.
    Zent R; Yan X; Su Y; Hudson BG; Borza DB; Moeckel GW; Qi Z; Sado Y; Breyer MD; Voziyan P; Pozzi A
    Kidney Int; 2006 Aug; 70(3):460-70. PubMed ID: 16775606
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Stage-specific action of matrix metalloproteinases influences progressive hereditary kidney disease.
    Zeisberg M; Khurana M; Rao VH; Cosgrove D; Rougier JP; Werner MC; Shield CF; Werb Z; Kalluri R
    PLoS Med; 2006 Apr; 3(4):e100. PubMed ID: 16509766
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Endothelin A receptor activation on mesangial cells initiates Alport glomerular disease.
    Dufek B; Meehan DT; Delimont D; Cheung L; Gratton MA; Phillips G; Song W; Liu S; Cosgrove D
    Kidney Int; 2016 Aug; 90(2):300-310. PubMed ID: 27165837
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Ramipril therapy in integrin α1-null, autosomal recessive Alport mice triples lifespan: mechanistic clues from RNA-seq analysis.
    Madison J; Wilhelm K; Meehan DT; Gratton MA; Vosik D; Samuelson G; Ott M; Fascianella J; Nelson N; Cosgrove D
    J Pathol; 2024 Mar; 262(3):296-309. PubMed ID: 38129319
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Biomechanical strain causes maladaptive gene regulation, contributing to Alport glomerular disease.
    Meehan DT; Delimont D; Cheung L; Zallocchi M; Sansom SC; Holzclaw JD; Rao V; Cosgrove D
    Kidney Int; 2009 Nov; 76(9):968-76. PubMed ID: 19710627
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Cellular origins of type IV collagen networks in developing glomeruli.
    Abrahamson DR; Hudson BG; Stroganova L; Borza DB; St John PL
    J Am Soc Nephrol; 2009 Jul; 20(7):1471-9. PubMed ID: 19423686
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Integrin alpha1beta1 controls reactive oxygen species synthesis by negatively regulating epidermal growth factor receptor-mediated Rac activation.
    Chen X; Abair TD; Ibanez MR; Su Y; Frey MR; Dise RS; Polk DB; Singh AB; Harris RC; Zent R; Pozzi A
    Mol Cell Biol; 2007 May; 27(9):3313-26. PubMed ID: 17339338
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Integrin alpha1beta1 regulates epidermal growth factor receptor activation by controlling peroxisome proliferator-activated receptor gamma-dependent caveolin-1 expression.
    Chen X; Whiting C; Borza C; Hu W; Mont S; Bulus N; Zhang MZ; Harris RC; Zent R; Pozzi A
    Mol Cell Biol; 2010 Jun; 30(12):3048-58. PubMed ID: 20368353
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Lysyl oxidase like-2 contributes to renal fibrosis in Col4α3/Alport mice.
    Cosgrove D; Dufek B; Meehan DT; Delimont D; Hartnett M; Samuelson G; Gratton MA; Phillips G; MacKenna DA; Bain G
    Kidney Int; 2018 Aug; 94(2):303-314. PubMed ID: 29759420
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Elevated matrix metalloprotease and angiostatin levels in integrin alpha 1 knockout mice cause reduced tumor vascularization.
    Pozzi A; Moberg PE; Miles LA; Wagner S; Soloway P; Gardner HA
    Proc Natl Acad Sci U S A; 2000 Feb; 97(5):2202-7. PubMed ID: 10681423
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Loss of integrin alpha1beta1 ameliorates Kras-induced lung cancer.
    Macias-Perez I; Borza C; Chen X; Yan X; Ibanez R; Mernaugh G; Matrisian LM; Zent R; Pozzi A
    Cancer Res; 2008 Aug; 68(15):6127-35. PubMed ID: 18676835
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Collagen receptors integrin alpha2beta1 and discoidin domain receptor 1 regulate maturation of the glomerular basement membrane and loss of integrin alpha2beta1 delays kidney fibrosis in COL4A3 knockout mice.
    Rubel D; Frese J; Martin M; Leibnitz A; Girgert R; Miosge N; Eckes B; Müller GA; Gross O
    Matrix Biol; 2014 Feb; 34():13-21. PubMed ID: 24480069
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Increased expression of MMP-2, MMP-9 (type IV collagenases/gelatinases), and MT1-MMP in canine X-linked Alport syndrome (XLAS).
    Rao VH; Lees GE; Kashtan CE; Nemori R; Singh RK; Meehan DT; Rodgers K; Berridge BR; Bhattacharya G; Cosgrove D
    Kidney Int; 2003 May; 63(5):1736-48. PubMed ID: 12675849
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Matrix metalloproteinase dysregulation in the stria vascularis of mice with Alport syndrome: implications for capillary basement membrane pathology.
    Gratton MA; Rao VH; Meehan DT; Askew C; Cosgrove D
    Am J Pathol; 2005 May; 166(5):1465-74. PubMed ID: 15855646
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.