BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

200 related articles for article (PubMed ID: 18258846)

  • 1. Integrin alpha1beta1 regulates matrix metalloproteinases via P38 mitogen-activated protein kinase in mesangial cells: implications for Alport syndrome.
    Cosgrove D; Meehan DT; Delimont D; Pozzi A; Chen X; Rodgers KD; Tempero RM; Zallocchi M; Rao VH
    Am J Pathol; 2008 Mar; 172(3):761-73. PubMed ID: 18258846
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Upregulated expression of integrin α1 in mesangial cells and integrin α3 and vimentin in podocytes of Col4a3-null (Alport) mice.
    Steenhard BM; Vanacore R; Friedman D; Zelenchuk A; Stroganova L; Isom K; St John PL; Hudson BG; Abrahamson DR
    PLoS One; 2012; 7(12):e50745. PubMed ID: 23236390
    [TBL] [Abstract][Full Text] [Related]  

  • 3. α1β1 integrin/Rac1-dependent mesangial invasion of glomerular capillaries in Alport syndrome.
    Zallocchi M; Johnson BM; Meehan DT; Delimont D; Cosgrove D
    Am J Pathol; 2013 Oct; 183(4):1269-1280. PubMed ID: 23911822
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Glomerular basement membrane deposition of collagen α1(III) in Alport glomeruli by mesangial filopodia injures podocytes via aberrant signaling through DDR1 and integrin α2β1.
    Madison J; Wilhelm K; Meehan DT; Delimont D; Samuelson G; Cosgrove D
    J Pathol; 2022 Sep; 258(1):26-37. PubMed ID: 35607980
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Laminin α2-mediated focal adhesion kinase activation triggers Alport glomerular pathogenesis.
    Delimont D; Dufek BM; Meehan DT; Zallocchi M; Gratton MA; Phillips G; Cosgrove D
    PLoS One; 2014; 9(6):e99083. PubMed ID: 24915008
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Integrin alpha1beta1 and transforming growth factor-beta1 play distinct roles in alport glomerular pathogenesis and serve as dual targets for metabolic therapy.
    Cosgrove D; Rodgers K; Meehan D; Miller C; Bovard K; Gilroy A; Gardner H; Kotelianski V; Gotwals P; Amatucci A; Kalluri R
    Am J Pathol; 2000 Nov; 157(5):1649-59. PubMed ID: 11073824
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Glomerular injury is exacerbated in diabetic integrin alpha1-null mice.
    Zent R; Yan X; Su Y; Hudson BG; Borza DB; Moeckel GW; Qi Z; Sado Y; Breyer MD; Voziyan P; Pozzi A
    Kidney Int; 2006 Aug; 70(3):460-70. PubMed ID: 16775606
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Stage-specific action of matrix metalloproteinases influences progressive hereditary kidney disease.
    Zeisberg M; Khurana M; Rao VH; Cosgrove D; Rougier JP; Werner MC; Shield CF; Werb Z; Kalluri R
    PLoS Med; 2006 Apr; 3(4):e100. PubMed ID: 16509766
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Endothelin A receptor activation on mesangial cells initiates Alport glomerular disease.
    Dufek B; Meehan DT; Delimont D; Cheung L; Gratton MA; Phillips G; Song W; Liu S; Cosgrove D
    Kidney Int; 2016 Aug; 90(2):300-310. PubMed ID: 27165837
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Ramipril therapy in integrin α1-null, autosomal recessive Alport mice triples lifespan: mechanistic clues from RNA-seq analysis.
    Madison J; Wilhelm K; Meehan DT; Gratton MA; Vosik D; Samuelson G; Ott M; Fascianella J; Nelson N; Cosgrove D
    J Pathol; 2024 Mar; 262(3):296-309. PubMed ID: 38129319
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Biomechanical strain causes maladaptive gene regulation, contributing to Alport glomerular disease.
    Meehan DT; Delimont D; Cheung L; Zallocchi M; Sansom SC; Holzclaw JD; Rao V; Cosgrove D
    Kidney Int; 2009 Nov; 76(9):968-76. PubMed ID: 19710627
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Cellular origins of type IV collagen networks in developing glomeruli.
    Abrahamson DR; Hudson BG; Stroganova L; Borza DB; St John PL
    J Am Soc Nephrol; 2009 Jul; 20(7):1471-9. PubMed ID: 19423686
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Integrin alpha1beta1 controls reactive oxygen species synthesis by negatively regulating epidermal growth factor receptor-mediated Rac activation.
    Chen X; Abair TD; Ibanez MR; Su Y; Frey MR; Dise RS; Polk DB; Singh AB; Harris RC; Zent R; Pozzi A
    Mol Cell Biol; 2007 May; 27(9):3313-26. PubMed ID: 17339338
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Integrin alpha1beta1 regulates epidermal growth factor receptor activation by controlling peroxisome proliferator-activated receptor gamma-dependent caveolin-1 expression.
    Chen X; Whiting C; Borza C; Hu W; Mont S; Bulus N; Zhang MZ; Harris RC; Zent R; Pozzi A
    Mol Cell Biol; 2010 Jun; 30(12):3048-58. PubMed ID: 20368353
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Lysyl oxidase like-2 contributes to renal fibrosis in Col4α3/Alport mice.
    Cosgrove D; Dufek B; Meehan DT; Delimont D; Hartnett M; Samuelson G; Gratton MA; Phillips G; MacKenna DA; Bain G
    Kidney Int; 2018 Aug; 94(2):303-314. PubMed ID: 29759420
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Elevated matrix metalloprotease and angiostatin levels in integrin alpha 1 knockout mice cause reduced tumor vascularization.
    Pozzi A; Moberg PE; Miles LA; Wagner S; Soloway P; Gardner HA
    Proc Natl Acad Sci U S A; 2000 Feb; 97(5):2202-7. PubMed ID: 10681423
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Loss of integrin alpha1beta1 ameliorates Kras-induced lung cancer.
    Macias-Perez I; Borza C; Chen X; Yan X; Ibanez R; Mernaugh G; Matrisian LM; Zent R; Pozzi A
    Cancer Res; 2008 Aug; 68(15):6127-35. PubMed ID: 18676835
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Collagen receptors integrin alpha2beta1 and discoidin domain receptor 1 regulate maturation of the glomerular basement membrane and loss of integrin alpha2beta1 delays kidney fibrosis in COL4A3 knockout mice.
    Rubel D; Frese J; Martin M; Leibnitz A; Girgert R; Miosge N; Eckes B; Müller GA; Gross O
    Matrix Biol; 2014 Feb; 34():13-21. PubMed ID: 24480069
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Increased expression of MMP-2, MMP-9 (type IV collagenases/gelatinases), and MT1-MMP in canine X-linked Alport syndrome (XLAS).
    Rao VH; Lees GE; Kashtan CE; Nemori R; Singh RK; Meehan DT; Rodgers K; Berridge BR; Bhattacharya G; Cosgrove D
    Kidney Int; 2003 May; 63(5):1736-48. PubMed ID: 12675849
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Matrix metalloproteinase dysregulation in the stria vascularis of mice with Alport syndrome: implications for capillary basement membrane pathology.
    Gratton MA; Rao VH; Meehan DT; Askew C; Cosgrove D
    Am J Pathol; 2005 May; 166(5):1465-74. PubMed ID: 15855646
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.