BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

248 related articles for article (PubMed ID: 18260647)

  • 1. Mechanism of product specificity of AdoMet methylation catalyzed by lysine methyltransferases: transcriptional factor p53 methylation by histone lysine methyltransferase SET7/9.
    Zhang X; Bruice TC
    Biochemistry; 2008 Mar; 47(9):2743-8. PubMed ID: 18260647
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Histone lysine methyltransferase SET7/9: formation of a water channel precedes each methyl transfer.
    Zhang X; Bruice TC
    Biochemistry; 2007 Dec; 46(51):14838-44. PubMed ID: 18044969
    [TBL] [Abstract][Full Text] [Related]  

  • 3. A quantum mechanics/molecular mechanics study of the catalytic mechanism and product specificity of viral histone lysine methyltransferase.
    Zhang X; Bruice TC
    Biochemistry; 2007 Aug; 46(34):9743-51. PubMed ID: 17676763
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Catalytic mechanism and product specificity of rubisco large subunit methyltransferase: QM/MM and MD investigations.
    Zhang X; Bruice TC
    Biochemistry; 2007 May; 46(18):5505-14. PubMed ID: 17429949
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Product specificity and mechanism of protein lysine methyltransferases: insights from the histone lysine methyltransferase SET8.
    Zhang X; Bruice TC
    Biochemistry; 2008 Jun; 47(25):6671-7. PubMed ID: 18512960
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Catalytic mechanism and product specificity of the histone lysine methyltransferase SET7/9: an ab initio QM/MM-FE study with multiple initial structures.
    Hu P; Zhang Y
    J Am Chem Soc; 2006 Feb; 128(4):1272-8. PubMed ID: 16433545
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Structural basis for the methylation site specificity of SET7/9.
    Couture JF; Collazo E; Hauk G; Trievel RC
    Nat Struct Mol Biol; 2006 Feb; 13(2):140-6. PubMed ID: 16415881
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Enzymatic mechanism and product specificity of SET-domain protein lysine methyltransferases.
    Zhang X; Bruice TC
    Proc Natl Acad Sci U S A; 2008 Apr; 105(15):5728-32. PubMed ID: 18391193
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Regulation of p53 activity through lysine methylation.
    Chuikov S; Kurash JK; Wilson JR; Xiao B; Justin N; Ivanov GS; McKinney K; Tempst P; Prives C; Gamblin SJ; Barlev NA; Reinberg D
    Nature; 2004 Nov; 432(7015):353-60. PubMed ID: 15525938
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Methylation-acetylation interplay activates p53 in response to DNA damage.
    Ivanov GS; Ivanova T; Kurash J; Ivanov A; Chuikov S; Gizatullin F; Herrera-Medina EM; Rauscher F; Reinberg D; Barlev NA
    Mol Cell Biol; 2007 Oct; 27(19):6756-69. PubMed ID: 17646389
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Structure and catalytic mechanism of the human histone methyltransferase SET7/9.
    Xiao B; Jing C; Wilson JR; Walker PA; Vasisht N; Kelly G; Howell S; Taylor IA; Blackburn GM; Gamblin SJ
    Nature; 2003 Feb; 421(6923):652-6. PubMed ID: 12540855
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Catalytic properties and kinetic mechanism of human recombinant Lys-9 histone H3 methyltransferase SUV39H1: participation of the chromodomain in enzymatic catalysis.
    Chin HG; Patnaik D; Estève PO; Jacobsen SE; Pradhan S
    Biochemistry; 2006 Mar; 45(10):3272-84. PubMed ID: 16519522
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Mechanism of histone lysine methyl transfer revealed by the structure of SET7/9-AdoMet.
    Kwon T; Chang JH; Kwak E; Lee CW; Joachimiak A; Kim YC; Lee J; Cho Y
    EMBO J; 2003 Jan; 22(2):292-303. PubMed ID: 12514135
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Structure of human lysine methyltransferase Smyd2 reveals insights into the substrate divergence in Smyd proteins.
    Xu S; Zhong C; Zhang T; Ding J
    J Mol Cell Biol; 2011 Oct; 3(5):293-300. PubMed ID: 21724641
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Mechanism of histone methylation catalyzed by protein lysine methyltransferase SET7/9 and origin of product specificity.
    Guo HB; Guo H
    Proc Natl Acad Sci U S A; 2007 May; 104(21):8797-802. PubMed ID: 17517655
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Mechanism of multiple lysine methylation by the SET domain enzyme Rubisco LSMT.
    Trievel RC; Flynn EM; Houtz RL; Hurley JH
    Nat Struct Biol; 2003 Jul; 10(7):545-52. PubMed ID: 12819771
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Quantum chemical modeling of enzymatic reactions: the case of histone lysine methyltransferase.
    Georgieva P; Himo F
    J Comput Chem; 2010 Jun; 31(8):1707-14. PubMed ID: 20082388
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Biochemical characterization of human SET and MYND domain-containing protein 2 methyltransferase.
    Wu J; Cheung T; Grande C; Ferguson AD; Zhu X; Theriault K; Code E; Birr C; Keen N; Chen H
    Biochemistry; 2011 Jul; 50(29):6488-97. PubMed ID: 21678921
    [TBL] [Abstract][Full Text] [Related]  

  • 19. S-adenosyl-L-methionine-dependent methyl transfer: observable precatalytic intermediates during DNA cytosine methylation.
    Youngblood B; Shieh FK; Buller F; Bullock T; Reich NO
    Biochemistry; 2007 Jul; 46(30):8766-75. PubMed ID: 17616174
    [TBL] [Abstract][Full Text] [Related]  

  • 20. How do SET-domain protein lysine methyltransferases achieve the methylation state specificity? Revisited by Ab initio QM/MM molecular dynamics simulations.
    Hu P; Wang S; Zhang Y
    J Am Chem Soc; 2008 Mar; 130(12):3806-13. PubMed ID: 18311969
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.