178 related articles for article (PubMed ID: 18262416)
1. Novel methylene-linked heterocyclic EP1 receptor antagonists.
Hall A; Bit RA; Brown SH; Chowdhury A; Giblin GM; Hurst DN; Kilford IR; Lewell X; Naylor A; Scoccitti T
Bioorg Med Chem Lett; 2008 Mar; 18(5):1592-7. PubMed ID: 18262416
[TBL] [Abstract][Full Text] [Related]
2. Discovery of novel biaryl heterocyclic EP1 receptor antagonists.
Hall A; Bit RA; Brown SH; Chaignot HM; Chessell IP; Coleman T; Giblin GM; Hurst DN; Kilford IR; Lewell XQ; Michel AD; Mohamed S; Naylor A; Novelli R; Skinner L; Spalding DJ; Tang SP; Wilson RJ
Bioorg Med Chem Lett; 2006 May; 16(10):2666-71. PubMed ID: 16503138
[TBL] [Abstract][Full Text] [Related]
3. Heterocyclic 1,7-disubstituted indole sulfonamides are potent and selective human EP3 receptor antagonists.
Hategan G; Polozov AM; Zeller W; Cao H; Mishra RK; Kiselyov AS; Ramirez J; Halldorsdottir G; Andrésson T; Gurney ME; Singh J
Bioorg Med Chem Lett; 2009 Dec; 19(23):6797-800. PubMed ID: 19836233
[TBL] [Abstract][Full Text] [Related]
4. Identification and optimization of novel 1,3,4-oxadiazole EP1 receptor antagonists.
Hall A; Brown SH; Chowdhury A; Giblin GM; Gibson M; Healy MP; Livermore DG; Wilson RJ; Naylor A; Rawlings DA; Roman S; Ward E; Willay C
Bioorg Med Chem Lett; 2007 Aug; 17(16):4450-5. PubMed ID: 17574410
[TBL] [Abstract][Full Text] [Related]
5. Discovery of a novel indole series of EP1 receptor antagonists by scaffold hopping.
Hall A; Billinton A; Brown SH; Chowdhury A; Giblin GM; Goldsmith P; Hurst DN; Naylor A; Patel S; Scoccitti T; Theobald PJ
Bioorg Med Chem Lett; 2008 Apr; 18(8):2684-90. PubMed ID: 18378447
[TBL] [Abstract][Full Text] [Related]
6. Non-acidic pyrazole EP1 receptor antagonists with in vivo analgesic efficacy.
Hall A; Billinton A; Brown SH; Clayton NM; Chowdhury A; Giblin GM; Goldsmith P; Hayhow TG; Hurst DN; Kilford IR; Naylor A; Passingham B; Winyard L
Bioorg Med Chem Lett; 2008 Jun; 18(11):3392-9. PubMed ID: 18462938
[TBL] [Abstract][Full Text] [Related]
7. Discovery of brain penetrant, soluble, pyrazole amide EP1 receptor antagonists.
Hall A; Billinton A; Bristow AK; Brown SH; Chowdhury A; Cutler L; Giblin GM; Goldsmith P; Hayhow TG; Kilford IR; Naylor A; Passingham B; Rawlings DA
Bioorg Med Chem Lett; 2008 Jul; 18(14):4027-32. PubMed ID: 18571922
[TBL] [Abstract][Full Text] [Related]
8. 2,3-Diarylthiophenes as selective EP1 receptor antagonists.
Ducharme Y; Blouin M; Carrière MC; Chateauneuf A; Côté B; Denis D; Frenette R; Greig G; Kargman S; Lamontagne S; Martins E; Nantel F; O'Neill G; Sawyer N; Metters KM; Friesen RW
Bioorg Med Chem Lett; 2005 Feb; 15(4):1155-60. PubMed ID: 15686932
[TBL] [Abstract][Full Text] [Related]
9. Discovery of novel aminothiadiazole amides as selective EP(3) receptor antagonists.
Hilfiker MA; Wang N; Hou X; Du Z; Pullen MA; Nord M; Nagilla R; Fries HE; Wu CW; Sulpizio AC; Jaworski JP; Morrow D; Edwards RM; Jin J
Bioorg Med Chem Lett; 2009 Aug; 19(15):4292-5. PubMed ID: 19487124
[TBL] [Abstract][Full Text] [Related]
10. Discovery of novel, non-acidic 1,5-biaryl pyrrole EP1 receptor antagonists.
Hall A; Atkinson S; Brown SH; Chessell IP; Chowdhury A; Giblin GM; Goldsmith P; Healy MP; Jandu KS; Johnson MR; Michel AD; Naylor A; Sweeting JA
Bioorg Med Chem Lett; 2007 Mar; 17(5):1200-5. PubMed ID: 17196385
[TBL] [Abstract][Full Text] [Related]
11. Discovery of a series of acrylic acids and their derivatives as chemical leads for selective EP3 receptor antagonists.
Asada M; Obitsu T; Nagase T; Sugimoto I; Yamaura Y; Sato K; Narita M; Ohuchida S; Nakai H; Toda M
Bioorg Med Chem; 2009 Sep; 17(18):6567-82. PubMed ID: 19700331
[TBL] [Abstract][Full Text] [Related]
12. Structure-activity relationships of 1,5-biaryl pyrroles as EP1 receptor antagonists.
Hall A; Atkinson S; Brown SH; Chessell IP; Chowdhury A; Clayton NM; Coleman T; Giblin GM; Gleave RJ; Hammond B; Healy MP; Johnson MR; Michel AD; Naylor A; Novelli R; Spalding DJ; Tang SP
Bioorg Med Chem Lett; 2006 Jul; 16(14):3657-62. PubMed ID: 16697196
[TBL] [Abstract][Full Text] [Related]
13. Discovery of new chemical leads for selective EP1 receptor antagonists.
Naganawa A; Saito T; Nagao Y; Egashira H; Iwahashi M; Kambe T; Koketsu M; Yamamoto H; Kobayashi M; Maruyama T; Ohuchida S; Nakai H; Kondo K; Toda M
Bioorg Med Chem; 2006 Aug; 14(16):5562-77. PubMed ID: 16697646
[TBL] [Abstract][Full Text] [Related]
14. Identification of novel glycine sulfonamide antagonists for the EP1 receptor.
McKeown SC; Hall A; Blunt R; Brown SH; Chessell IP; Chowdhury A; Giblin GM; Healy MP; Johnson MR; Lorthioir O; Michel AD; Naylor A; Lewell X; Roman S; Watson SP; Winchester WJ; Wilson RJ
Bioorg Med Chem Lett; 2007 Mar; 17(6):1750-4. PubMed ID: 17236765
[TBL] [Abstract][Full Text] [Related]
15. Optimization of sulfonamide derivatives as highly selective EP1 receptor antagonists.
Naganawa A; Matsui T; Ima M; Yoshida K; Tsuruta H; Yamamoto S; Yamamoto H; Okada H; Maruyama T; Nakai H; Kondo K; Toda M
Bioorg Med Chem; 2006 Dec; 14(23):7774-89. PubMed ID: 16931028
[TBL] [Abstract][Full Text] [Related]
16. Structure-activity relationship studies on ortho-substituted cinnamic acids, a new class of selective EP(3) antagonists.
Belley M; Gallant M; Roy B; Houde K; Lachance N; Labelle M; Trimble LA; Chauret N; Li C; Sawyer N; Tremblay N; Lamontagne S; Carrière MC; Denis D; Greig GM; Slipetz D; Metters KM; Gordon R; Chan CC; Zamboni RJ
Bioorg Med Chem Lett; 2005 Feb; 15(3):527-30. PubMed ID: 15664806
[TBL] [Abstract][Full Text] [Related]
17. Identification of novel pyrazole acid antagonists for the EP1 receptor.
McKeown SC; Hall A; Giblin GM; Lorthioir O; Blunt R; Lewell XQ; Wilson RJ; Brown SH; Chowdhury A; Coleman T; Watson SP; Chessell IP; Pipe A; Clayton N; Goldsmith P
Bioorg Med Chem Lett; 2006 Sep; 16(18):4767-71. PubMed ID: 16843659
[TBL] [Abstract][Full Text] [Related]
18. Synthesis and structure-activity relationship of a novel series of heterocyclic sulfonamide gamma-secretase inhibitors.
Pu J; Kreft AF; Aschmies SH; Atchison KP; Berkowitz J; Caggiano TJ; Chlenov M; Diamantidis G; Harrison BL; Hu Y; Huryn D; Steven Jacobsen J; Jin M; Lipinski K; Lu P; Martone RL; Morris K; Sonnenberg-Reines J; Riddell DR; Sabalski J; Sun SC; Wagner E; Wang Y; Xu Z; Zhou H; Resnick L
Bioorg Med Chem; 2009 Jul; 17(13):4708-17. PubMed ID: 19443228
[TBL] [Abstract][Full Text] [Related]
19. Azole derivatives as histamine H3 receptor antagonists, part 2: C-C and C-S coupled heterocycles.
Walter M; Isensee K; Kottke T; Ligneau X; Camelin JC; Schwartz JC; Stark H
Bioorg Med Chem Lett; 2010 Oct; 20(19):5883-6. PubMed ID: 20727744
[TBL] [Abstract][Full Text] [Related]
20. Novel 1,3-dicarbonyl compounds having 2(3H)-benzazolonic heterocycles as PPARgamma agonists.
Blanc-Delmas E; Lebegue N; Wallez V; Leclerc V; Yous S; Carato P; Farce A; Bennejean C; Renard P; Caignard DH; Audinot-Bouchez V; Chomarat P; Boutin J; Hennuyer N; Louche K; Carmona MC; Staels B; Pénicaud L; Casteilla L; Lonchampt M; Dacquet C; Chavatte P; Berthelot P; Lesieur D
Bioorg Med Chem; 2006 Nov; 14(22):7377-91. PubMed ID: 16887353
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
