BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

709 related articles for article (PubMed ID: 18263584)

  • 1. NFkappaB-dependent control of BACE1 promoter transactivation by Abeta42.
    Buggia-Prevot V; Sevalle J; Rossner S; Checler F
    J Biol Chem; 2008 Apr; 283(15):10037-47. PubMed ID: 18263584
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Nuclear factor-κB regulates βAPP and β- and γ-secretases differently at physiological and supraphysiological Aβ concentrations.
    Chami L; Buggia-Prévot V; Duplan E; Del Prete D; Chami M; Peyron JF; Checler F
    J Biol Chem; 2012 Jul; 287(29):24573-84. PubMed ID: 22654105
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Amyloid-β protein (Aβ) Glu11 is the major β-secretase site of β-site amyloid-β precursor protein-cleaving enzyme 1(BACE1), and shifting the cleavage site to Aβ Asp1 contributes to Alzheimer pathogenesis.
    Deng Y; Wang Z; Wang R; Zhang X; Zhang S; Wu Y; Staufenbiel M; Cai F; Song W
    Eur J Neurosci; 2013 Jun; 37(12):1962-9. PubMed ID: 23773065
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Presenilin-dependent gamma-secretase-mediated control of p53-associated cell death in Alzheimer's disease.
    Alves da Costa C; Sunyach C; Pardossi-Piquard R; Sévalle J; Vincent B; Boyer N; Kawarai T; Girardot N; St George-Hyslop P; Checler F
    J Neurosci; 2006 Jun; 26(23):6377-85. PubMed ID: 16763046
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Design and characterization of a new cell-permeant inhibitor of the beta-secretase BACE1.
    Lefranc-Jullien S; Lisowski V; Hernandez JF; Martinez J; Checler F
    Br J Pharmacol; 2005 May; 145(2):228-35. PubMed ID: 15753947
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Alternative Selection of β-Site APP-Cleaving Enzyme 1 (BACE1) Cleavage Sites in Amyloid β-Protein Precursor (APP) Harboring Protective and Pathogenic Mutations within the Aβ Sequence.
    Kimura A; Hata S; Suzuki T
    J Biol Chem; 2016 Nov; 291(46):24041-24053. PubMed ID: 27687728
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Melatonin regulates the transcription of βAPP-cleaving secretases mediated through melatonin receptors in human neuroblastoma SH-SY5Y cells.
    Panmanee J; Nopparat C; Chavanich N; Shukla M; Mukda S; Song W; Vincent B; Govitrapong P
    J Pineal Res; 2015 Oct; 59(3):308-20. PubMed ID: 26123100
    [TBL] [Abstract][Full Text] [Related]  

  • 8. In vivo beta-secretase 1 inhibition leads to brain Abeta lowering and increased alpha-secretase processing of amyloid precursor protein without effect on neuregulin-1.
    Sankaranarayanan S; Price EA; Wu G; Crouthamel MC; Shi XP; Tugusheva K; Tyler KX; Kahana J; Ellis J; Jin L; Steele T; Stachel S; Coburn C; Simon AJ
    J Pharmacol Exp Ther; 2008 Mar; 324(3):957-69. PubMed ID: 18156464
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Relationship between ubiquilin-1 and BACE1 in human Alzheimer's disease and APdE9 transgenic mouse brain and cell-based models.
    Natunen T; Takalo M; Kemppainen S; Leskelä S; Marttinen M; Kurkinen KMA; Pursiheimo JP; Sarajärvi T; Viswanathan J; Gabbouj S; Solje E; Tahvanainen E; Pirttimäki T; Kurki M; Paananen J; Rauramaa T; Miettinen P; Mäkinen P; Leinonen V; Soininen H; Airenne K; Tanzi RE; Tanila H; Haapasalo A; Hiltunen M
    Neurobiol Dis; 2016 Jan; 85():187-205. PubMed ID: 26563932
    [TBL] [Abstract][Full Text] [Related]  

  • 10. APPepsilon, the epsilon-secretase-derived N-terminal product of the beta-amyloid precursor protein, behaves as a type I protein and undergoes alpha-, beta-, and gamma-secretase cleavages.
    Lefranc-Jullien S; Sunyach C; Checler F
    J Neurochem; 2006 May; 97(3):807-17. PubMed ID: 16524370
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Melatonin ameliorates Aβ
    Chinchalongporn V; Shukla M; Govitrapong P
    J Pineal Res; 2018 May; 64(4):e12470. PubMed ID: 29352484
    [TBL] [Abstract][Full Text] [Related]  

  • 12. BACE1: the beta-secretase enzyme in Alzheimer's disease.
    Vassar R
    J Mol Neurosci; 2004; 23(1-2):105-14. PubMed ID: 15126696
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Inhibition of GSK3β-mediated BACE1 expression reduces Alzheimer-associated phenotypes.
    Ly PT; Wu Y; Zou H; Wang R; Zhou W; Kinoshita A; Zhang M; Yang Y; Cai F; Woodgett J; Song W
    J Clin Invest; 2013 Jan; 123(1):224-35. PubMed ID: 23202730
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Novel role of RanBP9 in BACE1 processing of amyloid precursor protein and amyloid beta peptide generation.
    Lakshmana MK; Yoon IS; Chen E; Bianchi E; Koo EH; Kang DE
    J Biol Chem; 2009 May; 284(18):11863-72. PubMed ID: 19251705
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Genes and mechanisms involved in beta-amyloid generation and Alzheimer's disease.
    Steiner H; Capell A; Leimer U; Haass C
    Eur Arch Psychiatry Clin Neurosci; 1999; 249(6):266-70. PubMed ID: 10653281
    [TBL] [Abstract][Full Text] [Related]  

  • 16. p53-dependent control of transactivation of the Pen2 promoter by presenilins.
    Dunys J; Sevalle J; Giaime E; Pardossi-Piquard R; Vitek MP; Renbaum P; Levy-Lahad E; Zhang YW; Xu H; Checler F; da Costa CA
    J Cell Sci; 2009 Nov; 122(Pt 21):4003-8. PubMed ID: 19889971
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The beta-secretase, BACE: a prime drug target for Alzheimer's disease.
    Vassar R
    J Mol Neurosci; 2001 Oct; 17(2):157-70. PubMed ID: 11816789
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Mutant presenilin 1 increases the expression and activity of BACE1.
    Giliberto L; Borghi R; Piccini A; Mangerini R; Sorbi S; Cirmena G; Garuti A; Ghetti B; Tagliavini F; Mughal MR; Mattson MP; Zhu X; Wang X; Guglielmotto M; Tamagno E; Tabaton M
    J Biol Chem; 2009 Apr; 284(14):9027-38. PubMed ID: 19196715
    [TBL] [Abstract][Full Text] [Related]  

  • 19. beta-Secretase inhibitor potency is decreased by aberrant beta-cleavage location of the "Swedish mutant" amyloid precursor protein.
    Yamakawa H; Yagishita S; Futai E; Ishiura S
    J Biol Chem; 2010 Jan; 285(3):1634-42. PubMed ID: 19926793
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Pharmacological evidences for DFK167-sensitive presenilin-independent gamma-secretase-like activity.
    Sevalle J; Ayral E; Hernandez JF; Martinez J; Checler F
    J Neurochem; 2009 Jul; 110(1):275-83. PubMed ID: 19457123
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 36.