339 related articles for article (PubMed ID: 18263593)
21. The insulin-like growth factor-I receptor kinase inhibitor, NVP-ADW742, sensitizes small cell lung cancer cell lines to the effects of chemotherapy.
Warshamana-Greene GS; Litz J; Buchdunger E; García-Echeverría C; Hofmann F; Krystal GW
Clin Cancer Res; 2005 Feb; 11(4):1563-71. PubMed ID: 15746061
[TBL] [Abstract][Full Text] [Related]
22. Insulin-like growth factor-1 receptor and ErbB kinase inhibitor combinations block proliferation and induce apoptosis through cyclin D1 reduction and Bax activation.
Wilsbacher JL; Zhang Q; Tucker LA; Hubbard RD; Sheppard GS; Bamaung NY; Fidanze SD; Wang GT; Hu X; Davidsen SK; Bell RL; Wang J
J Biol Chem; 2008 Aug; 283(35):23721-30. PubMed ID: 18559346
[TBL] [Abstract][Full Text] [Related]
23. Overexpression of CEACAM6 promotes insulin-like growth factor I-induced pancreatic adenocarcinoma cellular invasiveness.
Duxbury MS; Ito H; Benoit E; Zinner MJ; Ashley SW; Whang EE
Oncogene; 2004 Jul; 23(34):5834-42. PubMed ID: 15208677
[TBL] [Abstract][Full Text] [Related]
24. Insulin-like growth factor type-I receptor-dependent phosphorylation of extracellular signal-regulated kinase 1/2 but not Akt (protein kinase B) can be induced by picropodophyllin.
Vasilcanu R; Vasilcanu D; Sehat B; Yin S; Girnita A; Axelson M; Girnita L
Mol Pharmacol; 2008 Mar; 73(3):930-9. PubMed ID: 18070930
[TBL] [Abstract][Full Text] [Related]
25. Dual sphingosine kinase inhibitor SKI-II enhances sensitivity to 5-fluorouracil in hepatocellular carcinoma cells via suppression of osteopontin and FAK/IGF-1R signalling.
Grbčić P; Tomljanović I; Klobučar M; Kraljević Pavelić S; Lučin K; Sedić M
Biochem Biophys Res Commun; 2017 Jun; 487(4):782-788. PubMed ID: 28433634
[TBL] [Abstract][Full Text] [Related]
26. IGF-1R inhibition induces MEK phosphorylation to promote survival in colon carcinomas.
Wang Q; Zhang Y; Zhu J; Zheng H; Chen S; Chen L; Yang HS
Signal Transduct Target Ther; 2020 Aug; 5(1):153. PubMed ID: 32843616
[TBL] [Abstract][Full Text] [Related]
27. Age-related differences in insulin-like growth factor-1 receptor signaling regulates Akt/FOXO3a and ERK/Fos pathways in vascular smooth muscle cells.
Li M; Chiu JF; Gagne J; Fukagawa NK
J Cell Physiol; 2008 Nov; 217(2):377-87. PubMed ID: 18615585
[TBL] [Abstract][Full Text] [Related]
28. A novel small molecule inhibitor of FAK decreases growth of human pancreatic cancer.
Hochwald SN; Nyberg C; Zheng M; Zheng D; Wood C; Massoll NA; Magis A; Ostrov D; Cance WG; Golubovskaya VM
Cell Cycle; 2009 Aug; 8(15):2435-43. PubMed ID: 19571674
[TBL] [Abstract][Full Text] [Related]
29. Luteolin decreases IGF-II production and downregulates insulin-like growth factor-I receptor signaling in HT-29 human colon cancer cells.
Lim DY; Cho HJ; Kim J; Nho CW; Lee KW; Park JH
BMC Gastroenterol; 2012 Jan; 12():9. PubMed ID: 22269172
[TBL] [Abstract][Full Text] [Related]
30. The association of TP53 mutations with the resistance of colorectal carcinoma to the insulin-like growth factor-1 receptor inhibitor picropodophyllin.
Wang Q; Wei F; Lv G; Li C; Liu T; Hadjipanayis CG; Zhang G; Hao C; Bellail AC
BMC Cancer; 2013 Nov; 13():521. PubMed ID: 24182354
[TBL] [Abstract][Full Text] [Related]
31. Focal adhesion kinase is required for IGF-I-mediated growth of skeletal muscle cells via a TSC2/mTOR/S6K1-associated pathway.
Crossland H; Kazi AA; Lang CH; Timmons JA; Pierre P; Wilkinson DJ; Smith K; Szewczyk NJ; Atherton PJ
Am J Physiol Endocrinol Metab; 2013 Jul; 305(2):E183-93. PubMed ID: 23695213
[TBL] [Abstract][Full Text] [Related]
32. Dual silencing of insulin-like growth factor-I receptor and epidermal growth factor receptor in colorectal cancer cells is associated with decreased proliferation and enhanced apoptosis.
Kaulfuss S; Burfeind P; Gaedcke J; Scharf JG
Mol Cancer Ther; 2009 Apr; 8(4):821-33. PubMed ID: 19372555
[TBL] [Abstract][Full Text] [Related]
33. IGF-1/IGF-1R/FAK/YAP Transduction Signaling Prompts Growth Effects in Triple-Negative Breast Cancer (TNBC) Cells.
Rigiracciolo DC; Nohata N; Lappano R; Cirillo F; Talia M; Scordamaglia D; Gutkind JS; Maggiolini M
Cells; 2020 Apr; 9(4):. PubMed ID: 32325700
[TBL] [Abstract][Full Text] [Related]
34. Targeting Focal Adhesion Kinase and Resistance to mTOR Inhibition in Pancreatic Neuroendocrine Tumors.
François RA; Maeng K; Nawab A; Kaye FJ; Hochwald SN; Zajac-Kaye M
J Natl Cancer Inst; 2015 Aug; 107(8):. PubMed ID: 25971297
[TBL] [Abstract][Full Text] [Related]
35. Inhibiting IGF-1R attenuates cell proliferation and VEGF production in IGF-1R over-expressing EGFR mutant non-small cell lung cancer cells.
Yeo CD; Kim YA; Lee HY; Kim JW; Lee SH; Kim SJ; Kwon SS; Kim YH; Kim SC
Exp Lung Res; 2017 Feb; 43(1):29-37. PubMed ID: 28394654
[TBL] [Abstract][Full Text] [Related]
36. Complement component 1, q subcomponent binding protein (C1QBP) in lipid rafts mediates hepatic metastasis of pancreatic cancer by regulating IGF-1/IGF-1R signaling.
Shi H; Fang W; Liu M; Fu D
Int J Cancer; 2017 Oct; 141(7):1389-1401. PubMed ID: 28608366
[TBL] [Abstract][Full Text] [Related]
37. ERK phosphorylation is predictive of resistance to IGF-1R inhibition in small cell lung cancer.
Zinn RL; Gardner EE; Marchionni L; Murphy SC; Dobromilskaya I; Hann CL; Rudin CM
Mol Cancer Ther; 2013 Jun; 12(6):1131-9. PubMed ID: 23515613
[TBL] [Abstract][Full Text] [Related]
38. Direct interaction of the N-terminal domain of focal adhesion kinase with the N-terminal transactivation domain of p53.
Golubovskaya VM; Finch R; Cance WG
J Biol Chem; 2005 Jul; 280(26):25008-21. PubMed ID: 15855171
[TBL] [Abstract][Full Text] [Related]
39. Insulin growth factor 1 receptor/PI3K/AKT survival pathway in outer segment membranes of rod photoreceptors.
Dilly AK; Rajala RV
Invest Ophthalmol Vis Sci; 2008 Nov; 49(11):4765-73. PubMed ID: 18566464
[TBL] [Abstract][Full Text] [Related]
40. FAK inhibition radiosensitizes pancreatic ductal adenocarcinoma cells in vitro.
Mohamed AA; Thomsen A; Follo M; Zamboglou C; Bronsert P; Mostafa H; Amen A; Mekawy M; Grosu AL; Brunner TB
Strahlenther Onkol; 2021 Jan; 197(1):27-38. PubMed ID: 32705304
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]
