195 related articles for article (PubMed ID: 18272172)
1. A splice site mutation in hERG leads to cryptic splicing in human long QT syndrome.
Gong Q; Zhang L; Moss AJ; Vincent GM; Ackerman MJ; Robinson JC; Jones MA; Tester DJ; Zhou Z
J Mol Cell Cardiol; 2008 Mar; 44(3):502-9. PubMed ID: 18272172
[TBL] [Abstract][Full Text] [Related]
2. Multiple splicing defects caused by hERG splice site mutation 2592+1G>A associated with long QT syndrome.
Stump MR; Gong Q; Zhou Z
Am J Physiol Heart Circ Physiol; 2011 Jan; 300(1):H312-8. PubMed ID: 21057041
[TBL] [Abstract][Full Text] [Related]
3. Nonsense mutations in hERG cause a decrease in mutant mRNA transcripts by nonsense-mediated mRNA decay in human long-QT syndrome.
Gong Q; Zhang L; Vincent GM; Horne BD; Zhou Z
Circulation; 2007 Jul; 116(1):17-24. PubMed ID: 17576861
[TBL] [Abstract][Full Text] [Related]
4. Early LQT2 nonsense mutation generates N-terminally truncated hERG channels with altered gating properties by the reinitiation of translation.
Stump MR; Gong Q; Packer JD; Zhou Z
J Mol Cell Cardiol; 2012 Nov; 53(5):725-33. PubMed ID: 22964610
[TBL] [Abstract][Full Text] [Related]
5. HERG-F463L potassium channels linked to long QT syndrome reduce I(Kr) current by a trafficking-deficient mechanism.
Yang HT; Sun CF; Cui CC; Xue XL; Zhang AF; Li HB; Wang DQ; Shu J
Clin Exp Pharmacol Physiol; 2009 Aug; 36(8):822-7. PubMed ID: 19215240
[TBL] [Abstract][Full Text] [Related]
6. [The mechanistic rote of KCNH2 gene L413P and L559H mutations in long QT syndrome].
Li CL; Hu DY; Liu WL; Qi SY; Wang HT; Li L; Gong QM; Zhou ZF
Zhonghua Nei Ke Za Zhi; 2007 Oct; 46(10):838-41. PubMed ID: 18218237
[TBL] [Abstract][Full Text] [Related]
7. Mechanism of loss of Kv11.1 K+ current in mutant T421M-Kv11.1-expressing rat ventricular myocytes: interaction of trafficking and gating.
Balijepalli SY; Lim E; Concannon SP; Chew CL; Holzem KE; Tester DJ; Ackerman MJ; Delisle BP; Balijepalli RC; January CT
Circulation; 2012 Dec; 126(24):2809-18. PubMed ID: 23136156
[TBL] [Abstract][Full Text] [Related]
8. L539 fs/47, a truncated mutation of human ether-a-go-go-related gene (hERG), decreases hERG ion channel currents in HEK 293 cells.
Zhang A; Sun C; Zhang L; Lv Y; Xue X; Li G; Cui C; Yan GX
Clin Exp Pharmacol Physiol; 2013 Jan; 40(1):28-36. PubMed ID: 23134353
[TBL] [Abstract][Full Text] [Related]
9. Identification and functional characterization of the human ether-a-go-go-related gene Q738X mutant associated with hereditary long QT syndrome type 2.
Han SN; Yang SH; Zhang Y; Sun XY; Duan YY; Hu XJ; Fan TL; Huang CZ; Yang G; Zhang Z; Zhang L
Int J Mol Med; 2014 Sep; 34(3):810-5. PubMed ID: 24993425
[TBL] [Abstract][Full Text] [Related]
10. Mouse ERG K(+) channel clones reveal differences in protein trafficking and function.
Lin EC; Moungey BM; Lim E; Concannon SP; Anderson CL; Kyle JW; Makielski JC; Balijepalli SY; January CT
J Am Heart Assoc; 2014 Dec; 3(6):e001491. PubMed ID: 25497881
[TBL] [Abstract][Full Text] [Related]
11. HERG mutation predicts short QT based on channel kinetics but causes long QT by heterotetrameric trafficking deficiency.
Paulussen AD; Raes A; Jongbloed RJ; Gilissen RA; Wilde AA; Snyders DJ; Smeets HJ; Aerssens J
Cardiovasc Res; 2005 Aug; 67(3):467-75. PubMed ID: 15958262
[TBL] [Abstract][Full Text] [Related]
12. Identification of Kv11.1 isoform switch as a novel pathogenic mechanism of long-QT syndrome.
Gong Q; Stump MR; Deng V; Zhang L; Zhou Z
Circ Cardiovasc Genet; 2014 Aug; 7(4):482-90. PubMed ID: 25028483
[TBL] [Abstract][Full Text] [Related]
13. Long QT syndrome-associated I593R mutation in HERG potassium channel activates ER stress pathways.
Keller SH; Platoshyn O; Yuan JX
Cell Biochem Biophys; 2005; 43(3):365-77. PubMed ID: 16244363
[TBL] [Abstract][Full Text] [Related]
14. Novel characteristics of a trafficking-defective G572R-hERG channel linked to hereditary long QT syndrome.
Lian J; Huang N; Zhou J; Ge S; Huang X; Huo J; Liu L; Xu W; Zhang S; Yang X; Zhou J; Huang C
Can J Cardiol; 2010 Oct; 26(8):417-22. PubMed ID: 20931094
[TBL] [Abstract][Full Text] [Related]
15. Trafficking defect and proteasomal degradation contribute to the phenotype of a novel KCNH2 long QT syndrome mutation.
Mihic A; Chauhan VS; Gao X; Oudit GY; Tsushima RG
PLoS One; 2011 Mar; 6(3):e18273. PubMed ID: 21483829
[TBL] [Abstract][Full Text] [Related]
16. Human ether-a-go-go related gene (hERG) K+ channels: function and dysfunction.
Perrin MJ; Subbiah RN; Vandenberg JI; Hill AP
Prog Biophys Mol Biol; 2008; 98(2-3):137-48. PubMed ID: 19027781
[TBL] [Abstract][Full Text] [Related]
17. A trafficking-deficient KCNQ1 mutation, T587M, causes a severe phenotype of long QT syndrome by interfering with intracellular hERG transport.
Wu J; Sakaguchi T; Takenaka K; Toyoda F; Tsuji K; Matsuura H; Horie M
J Cardiol; 2019 May; 73(5):343-350. PubMed ID: 30591322
[TBL] [Abstract][Full Text] [Related]
18. The G604S-hERG mutation alters the biophysical properties and exerts a dominant-negative effect on expression of hERG channels in HEK293 cells.
Huo J; Zhang Y; Huang N; Liu P; Huang C; Guo X; Jiang W; Zhou N; Grace A; Huang CL; Ma A
Pflugers Arch; 2008 Aug; 456(5):917-28. PubMed ID: 18386051
[TBL] [Abstract][Full Text] [Related]
19. The binding site for channel blockers that rescue misprocessed human long QT syndrome type 2 ether-a-gogo-related gene (HERG) mutations.
Ficker E; Obejero-Paz CA; Zhao S; Brown AM
J Biol Chem; 2002 Feb; 277(7):4989-98. PubMed ID: 11741928
[TBL] [Abstract][Full Text] [Related]
20. [Functional expression of congenital long QT syndrome related HERG mutation A561V in vitro].
Li Y; Cui CC; Zhao YH; Xue XL; Zhang AF; Lian JF; Huang C
Zhonghua Xin Xue Guan Bing Za Zhi; 2007 Feb; 35(2):143-6. PubMed ID: 17445409
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
