These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

135 related articles for article (PubMed ID: 18272369)

  • 1. Kinetic parameters and recognition of thymidine analogues with varying functional groups by thymidine phosphorylase.
    Hatano A; Harano A; Takigawa Y; Naramoto Y; Toda K; Nakagomi Y; Yamada H
    Bioorg Med Chem; 2008 Apr; 16(7):3866-70. PubMed ID: 18272369
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Substrate specificity of thymidine phosphorylase of E. coli: role of hydroxyl groups.
    Panova NG; Alexeev CS; Polyakov KM; Gavryushov SA; Kritzyn AM; Mikhailov SN
    Nucleosides Nucleotides Nucleic Acids; 2008 Dec; 27(12):1211-4. PubMed ID: 19003566
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Identification of aspartic acid-203 in human thymidine phosphorylase as an important residue for both catalysis and non-competitive inhibition by the small molecule "crystallization chaperone" 5'-O-tritylinosine (KIN59).
    Bronckaers A; Aguado L; Negri A; Camarasa MJ; Balzarini J; Pérez-Pérez MJ; Gago F; Liekens S
    Biochem Pharmacol; 2009 Aug; 78(3):231-40. PubMed ID: 19389384
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Role of histidine-85 in the catalytic mechanism of thymidine phosphorylase as assessed by targeted molecular dynamics simulations and quantum mechanical calculations.
    Mendieta J; Martín-Santamaría S; Priego EM; Balzarini J; Camarasa MJ; Pérez-Pérez MJ; Gago F
    Biochemistry; 2004 Jan; 43(2):405-14. PubMed ID: 14717594
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Substrate specificity of Escherichia coli thymidine phosphorylase.
    Panova NG; Alexeev CS; Kuzmichov AS; Shcheveleva EV; Gavryushov SA; Polyakov KM; Kritzyn AM; Mikhailov SN; Esipov RS; Miroshnikov AI
    Biochemistry (Mosc); 2007 Jan; 72(1):21-8. PubMed ID: 17309433
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Binding causes the remote [5'-3H]thymidine kinetic isotope effect in human thymidine phosphorylase.
    Birck MR; Schramm VL
    J Am Chem Soc; 2004 Jun; 126(22):6882-3. PubMed ID: 15174854
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Characterization of pyrimidine nucleoside phosphorylase of Mycoplasma hyorhinis: implications for the clinical efficacy of nucleoside analogues.
    Vande Voorde J; Gago F; Vrancken K; Liekens S; Balzarini J
    Biochem J; 2012 Jul; 445(1):113-23. PubMed ID: 22475552
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Nucleophilic participation in the transition state for human thymidine phosphorylase.
    Birck MR; Schramm VL
    J Am Chem Soc; 2004 Mar; 126(8):2447-53. PubMed ID: 14982453
    [TBL] [Abstract][Full Text] [Related]  

  • 9. One-pot approach to functional nucleosides possessing a fluorescent group using nucleobase-exchange reaction by thymidine phosphorylase.
    Hatano A; Kurosu M; Yonaha S; Okada M; Uehara S
    Org Biomol Chem; 2013 Sep; 11(40):6900-5. PubMed ID: 24057401
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Kinetics mechanism and regulation of native human hepatic thymidine phosphorylase.
    Oh T; El Kouni MH
    Int J Biochem Cell Biol; 2019 May; 110():122-129. PubMed ID: 30849523
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The role of phosphate in the action of thymidine phosphorylase inhibitors: Implications for the catalytic mechanism.
    Jain HV; Rasheed R; Kalman TI
    Bioorg Med Chem Lett; 2010 Mar; 20(5):1648-51. PubMed ID: 20138520
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Structural diversity of nucleoside phosphonic acids as a key factor in the discovery of potent inhibitors of rat T-cell lymphoma thymidine phosphorylase.
    Kocalka P; Rejman D; Vanek V; Rinnová M; Tomecková I; Králíková S; Petrová M; Páv O; Pohl R; Budesínský M; Liboska R; Tocík Z; Panova N; Votruba I; Rosenberg I
    Bioorg Med Chem Lett; 2010 Feb; 20(3):862-5. PubMed ID: 20053558
    [TBL] [Abstract][Full Text] [Related]  

  • 13. 3'-Azidothymidine in the active site of Escherichia coli thymidine phosphorylase: the peculiarity of the binding on the basis of X-ray study.
    Timofeev V; Abramchik Y; Zhukhlistova N; Muravieva T; Fateev I; Esipov R; Kuranova I
    Acta Crystallogr D Biol Crystallogr; 2014 Apr; 70(Pt 4):1155-65. PubMed ID: 24699659
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Phosphoramidate pronucleotides: a comparison of the phosphoramidase substrate specificity of human and Escherichia coli histidine triad nucleotide binding proteins.
    Chou TF; Baraniak J; Kaczmarek R; Zhou X; Cheng J; Ghosh B; Wagner CR
    Mol Pharm; 2007; 4(2):208-17. PubMed ID: 17217311
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Synthesis and evaluation of 6-methylene-bridged uracil derivatives. Part 2: optimization of inhibitors of human thymidine phosphorylase and their selectivity with uridine phosphorylase.
    Yano S; Kazuno H; Sato T; Suzuki N; Emura T; Wierzba K; Yamashita J; Tada Y; Yamada Y; Fukushima M; Asao T
    Bioorg Med Chem; 2004 Jul; 12(13):3443-50. PubMed ID: 15186830
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Targeting platelet-derived endothelial cell growth factor/thymidine phosphorylase for cancer therapy.
    Liekens S; Bronckaers A; Pérez-Pérez MJ; Balzarini J
    Biochem Pharmacol; 2007 Dec; 74(11):1555-67. PubMed ID: 17572389
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Determination of thymidine phosphorylase activity by a non-radiochemical assay using reversed-phase high-performance liquid chromatography.
    van Kuilenburg AB; Zoetekouw L
    J Chromatogr B Analyt Technol Biomed Life Sci; 2005 Jun; 820(2):271-275. PubMed ID: 15893964
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Expansion of repertoire of modified DNAs prepared by PCR using KOD Dash DNA polymerase.
    Ohbayashi T; Kuwahara M; Hasegawa M; Kasamatsu T; Tamura T; Sawai H
    Org Biomol Chem; 2005 Jul; 3(13):2463-8. PubMed ID: 15976864
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Synthesis, anti-thymidine phosphorylase activity and molecular docking of 5-thioxo-[1,2,4]triazolo[1,5-a][1,3,5]triazin-7-ones.
    Bera H; Lee MH; Sun L; Dolzhenko AV; Chui WK
    Bioorg Chem; 2013 Oct; 50():34-40. PubMed ID: 23968897
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Thymidine phosphorylase from Escherichia coli: tight-binding inhibitors as enzyme active-site titrants.
    Gbaj A; Edwards PN; Reigan P; Freeman S; Jaffar M; Douglas KT
    J Enzyme Inhib Med Chem; 2006 Feb; 21(1):69-73. PubMed ID: 16570508
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.