190 related articles for article (PubMed ID: 18275607)
1. Preclinical studies of Apogossypolone: a new nonpeptidic pan small-molecule inhibitor of Bcl-2, Bcl-XL and Mcl-1 proteins in Follicular Small Cleaved Cell Lymphoma model.
Arnold AA; Aboukameel A; Chen J; Yang D; Wang S; Al-Katib A; Mohammad RM
Mol Cancer; 2008 Feb; 7():20. PubMed ID: 18275607
[TBL] [Abstract][Full Text] [Related]
2. Apogossypolone, a nonpeptidic small molecule inhibitor targeting Bcl-2 family proteins, effectively inhibits growth of diffuse large cell lymphoma cells in vitro and in vivo.
Sun Y; Wu J; Aboukameel A; Banerjee S; Arnold AA; Chen J; Nikolovska-Coleska Z; Lin Y; Ling X; Yang D; Wang S; Al-Katib A; Mohammad RM
Cancer Biol Ther; 2008 Sep; 7(9):1418-26. PubMed ID: 18769131
[TBL] [Abstract][Full Text] [Related]
3. Preclinical studies of apogossypolone, a novel pan inhibitor of bcl-2 and mcl-1, synergistically potentiates cytotoxic effect of gemcitabine in pancreatic cancer cells.
Banerjee S; Choi M; Aboukameel A; Wang Z; Mohammad M; Chen J; Yang D; Sarkar FH; Mohammad RM
Pancreas; 2010 Apr; 39(3):323-31. PubMed ID: 19823097
[TBL] [Abstract][Full Text] [Related]
4. Preclinical studies of a nonpeptidic small-molecule inhibitor of Bcl-2 and Bcl-X(L) [(-)-gossypol] against diffuse large cell lymphoma.
Mohammad RM; Wang S; Aboukameel A; Chen B; Wu X; Chen J; Al-Katib A
Mol Cancer Ther; 2005 Jan; 4(1):13-21. PubMed ID: 15657349
[TBL] [Abstract][Full Text] [Related]
5. Synergistic antitumoral activity and induction of apoptosis by novel pan Bcl-2 proteins inhibitor apogossypolone with adriamycin in human hepatocellular carcinoma.
Mi JX; Wang GF; Wang HB; Sun XQ; Ni XY; Zhang XW; Tang JM; Yang DJ
Acta Pharmacol Sin; 2008 Dec; 29(12):1467-77. PubMed ID: 19026166
[TBL] [Abstract][Full Text] [Related]
6. ApoG2 inhibits antiapoptotic Bcl-2 family proteins and induces mitochondria-dependent apoptosis in human lymphoma U937 cells.
Sun J; Li ZM; Hu ZY; Lin XB; Zhou NN; Xian LJ; Yang DJ; Jiang WQ
Anticancer Drugs; 2008 Nov; 19(10):967-74. PubMed ID: 18827561
[TBL] [Abstract][Full Text] [Related]
7. Preclinical studies of TW-37, a new nonpeptidic small-molecule inhibitor of Bcl-2, in diffuse large cell lymphoma xenograft model reveal drug action on both Bcl-2 and Mcl-1.
Mohammad RM; Goustin AS; Aboukameel A; Chen B; Banerjee S; Wang G; Nikolovska-Coleska Z; Wang S; Al-Katib A
Clin Cancer Res; 2007 Apr; 13(7):2226-35. PubMed ID: 17404107
[TBL] [Abstract][Full Text] [Related]
8. Apogossypolone induces autophagy and apoptosis in breast cancer MCF-7 cells in vitro and in vivo.
Niu X; Li S; Wei F; Huang J; Wu G; Xu L; Xu D; Wang S
Breast Cancer; 2014 Mar; 21(2):223-30. PubMed ID: 22711315
[TBL] [Abstract][Full Text] [Related]
9. DT2216-a Bcl-xL-specific degrader is highly active against Bcl-xL-dependent T cell lymphomas.
He Y; Koch R; Budamagunta V; Zhang P; Zhang X; Khan S; Thummuri D; Ortiz YT; Zhang X; Lv D; Wiegand JS; Li W; Palmer AC; Zheng G; Weinstock DM; Zhou D
J Hematol Oncol; 2020 Jul; 13(1):95. PubMed ID: 32677976
[TBL] [Abstract][Full Text] [Related]
10. Apogossypolone, a small-molecule inhibitor of Bcl-2, induces radiosensitization of nasopharyngeal carcinoma cells by stimulating autophagy.
He JH; Liao XL; Wang W; Li DD; Chen WD; Deng R; Yang D; Han ZP; Jiang JW; Zhu XF
Int J Oncol; 2014 Sep; 45(3):1099-108. PubMed ID: 24919770
[TBL] [Abstract][Full Text] [Related]
11. ApoG2, a novel inhibitor of antiapoptotic Bcl-2 family proteins, induces apoptosis and suppresses tumor growth in nasopharyngeal carcinoma xenografts.
Hu ZY; Zhu XF; Zhong ZD; Sun J; Wang J; Yang D; Zeng YX
Int J Cancer; 2008 Nov; 123(10):2418-29. PubMed ID: 18712728
[TBL] [Abstract][Full Text] [Related]
12. ApoG2 inhibits the antiapoptotic protein, Mcl‑1, and induces mitochondria‑dependent apoptosis in human colorectal cancer cells.
Li T; Yuan G; Zhang L; Ye L; Li S; Fan Y; Sun J
Mol Med Rep; 2015 Nov; 12(5):6976-84. PubMed ID: 26352605
[TBL] [Abstract][Full Text] [Related]
13. Apogossypolone inhibits the proliferation of LNCaP cells in vitro and in vivo.
Zhang X; Hu X; Mu S; Zhan Y; An Q; Liu Z; Huang X
Mol Med Rep; 2014 Sep; 10(3):1184-94. PubMed ID: 25060748
[TBL] [Abstract][Full Text] [Related]
14. Bcl-2 antisense oligonucleotides are effective against systemic but not central nervous system disease in severe combined immunodeficient mice bearing human t(14;18) follicular lymphoma.
Mohammad R; Abubakr Y; Dan M; Aboukameel A; Chow C; Mohamed A; Hamdy N; Al-Katib A
Clin Cancer Res; 2002 Apr; 8(4):1277-83. PubMed ID: 11948143
[TBL] [Abstract][Full Text] [Related]
15. Induction of apoptosis and antitumor effects of a small molecule inhibitor of Bcl-2 and Bcl-xl, gossypol acetate, in multiple myeloma in vitro and in vivo.
Lin J; Wu Y; Yang D; Zhao Y
Oncol Rep; 2013 Aug; 30(2):731-8. PubMed ID: 23708869
[TBL] [Abstract][Full Text] [Related]
16. Natural BH3 mimetic (-)-gossypol chemosensitizes human prostate cancer via Bcl-xL inhibition accompanied by increase of Puma and Noxa.
Meng Y; Tang W; Dai Y; Wu X; Liu M; Ji Q; Ji M; Pienta K; Lawrence T; Xu L
Mol Cancer Ther; 2008 Jul; 7(7):2192-202. PubMed ID: 18645028
[TBL] [Abstract][Full Text] [Related]
17. Synthesis and biological evaluation of Apogossypolone derivatives as pan-active inhibitors of antiapoptotic B-cell lymphoma/leukemia-2 (Bcl-2) family proteins.
Wei J; Kitada S; Stebbins JL; Placzek W; Zhai D; Wu B; Rega MF; Zhang Z; Cellitti J; Yang L; Dahl R; Reed JC; Pellecchia M
J Med Chem; 2010 Nov; 53(22):8000-11. PubMed ID: 21033669
[TBL] [Abstract][Full Text] [Related]
18. An MDM2 antagonist (MI-319) restores p53 functions and increases the life span of orally treated follicular lymphoma bearing animals.
Mohammad RM; Wu J; Azmi AS; Aboukameel A; Sosin A; Wu S; Yang D; Wang S; Al-Katib AM
Mol Cancer; 2009 Dec; 8():115. PubMed ID: 19958544
[TBL] [Abstract][Full Text] [Related]
19. Nonpeptidic small-molecule inhibitor of Bcl-2 and Bcl-XL, (-)-Gossypol, enhances biological effect of genistein against BxPC-3 human pancreatic cancer cell line.
Mohammad RM; Wang S; Banerjee S; Wu X; Chen J; Sarkar FH
Pancreas; 2005 Nov; 31(4):317-24. PubMed ID: 16258364
[TBL] [Abstract][Full Text] [Related]
20. Enhanced efficacy of therapy with antisense BCL-2 oligonucleotides plus anti-CD20 monoclonal antibody in scid mouse/human lymphoma xenografts.
Smith MR; Jin F; Joshi I
Mol Cancer Ther; 2004 Dec; 3(12):1693-9. PubMed ID: 15634664
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
