329 related articles for article (PubMed ID: 18276834)
1. Scaling of in vitro membrane permeability to predict P-glycoprotein-mediated drug absorption in vivo.
Shirasaka Y; Masaoka Y; Kataoka M; Sakuma S; Yamashita S
Drug Metab Dispos; 2008 May; 36(5):916-22. PubMed ID: 18276834
[TBL] [Abstract][Full Text] [Related]
2. Permeability dominates in vivo intestinal absorption of P-gp substrate with high solubility and high permeability.
Cao X; Yu LX; Barbaciru C; Landowski CP; Shin HC; Gibbs S; Miller HA; Amidon GL; Sun D
Mol Pharm; 2005; 2(4):329-40. PubMed ID: 16053336
[TBL] [Abstract][Full Text] [Related]
3. pH-dependent functional activity of P-glycoprotein in limiting intestinal absorption of protic drugs: kinetic analysis of quinidine efflux in situ.
Varma MV; Panchagnula R
J Pharm Sci; 2005 Dec; 94(12):2632-43. PubMed ID: 16258992
[TBL] [Abstract][Full Text] [Related]
4. In situ kinetic modelling of intestinal efflux in rats: functional characterization of segmental differences and correlation with in vitro results.
González-Alvarez I; Fernández-Teruel C; Casabó-Alós VG; Garrigues TM; Polli JE; Ruiz-García A; Bermejo M
Biopharm Drug Dispos; 2007 Jul; 28(5):229-39. PubMed ID: 17410527
[TBL] [Abstract][Full Text] [Related]
5. Segmental dependent transport of low permeability compounds along the small intestine due to P-glycoprotein: the role of efflux transport in the oral absorption of BCS class III drugs.
Dahan A; Amidon GL
Mol Pharm; 2009; 6(1):19-28. PubMed ID: 19248230
[TBL] [Abstract][Full Text] [Related]
6. pH-dependent functional activity of P-glycoprotein in limiting intestinal absorption of protic drugs 1. Simultaneous determination of quinidine and permeability markers in rat in situ perfusion samples.
Varma MV; Sarkar M; Kapoor N; Panchagnula R
J Chromatogr B Analyt Technol Biomed Life Sci; 2005 Feb; 816(1-2):243-9. PubMed ID: 15664356
[TBL] [Abstract][Full Text] [Related]
7. Transport of rhodamine 123, a P-glycoprotein substrate, across rat intestine and Caco-2 cell monolayers in the presence of cytochrome P-450 3A-related compounds.
Yumoto R; Murakami T; Nakamoto Y; Hasegawa R; Nagai J; Takano M
J Pharmacol Exp Ther; 1999 Apr; 289(1):149-55. PubMed ID: 10086998
[TBL] [Abstract][Full Text] [Related]
8. Effect of P-glycoprotein expression levels on the concentration-dependent permeability of drugs to the cell membrane.
Shirasaka Y; Sakane T; Yamashita S
J Pharm Sci; 2008 Jan; 97(1):553-65. PubMed ID: 17828734
[TBL] [Abstract][Full Text] [Related]
9. Characterization of binding properties to human P-glycoprotein: development of a [3H]verapamil radioligand-binding assay.
Döppenschmitt S; Langguth P; Regårdh CG; Andersson TB; Hilgendorf C; Spahn-Langguth H
J Pharmacol Exp Ther; 1999 Jan; 288(1):348-57. PubMed ID: 9862789
[TBL] [Abstract][Full Text] [Related]
10. P-glycoprotein limits the absorption of the anti-HIV drug zidovudine through rat intestinal segments.
Quevedo MA; Nieto LE; Briñón MC
Eur J Pharm Sci; 2011 Jun; 43(3):151-9. PubMed ID: 21540109
[TBL] [Abstract][Full Text] [Related]
11. Co-treatment with grapefruit juice inhibits while chronic administration activates intestinal P-glycoprotein-mediated drug efflux.
Panchagnula R; Bansal T; Varma MV; Kaul CL
Pharmazie; 2005 Dec; 60(12):922-7. PubMed ID: 16398269
[TBL] [Abstract][Full Text] [Related]
12. Functional role of P-glycoprotein in limiting intestinal absorption of drugs: contribution of passive permeability to P-glycoprotein mediated efflux transport.
Varma MV; Sateesh K; Panchagnula R
Mol Pharm; 2005; 2(1):12-21. PubMed ID: 15804173
[TBL] [Abstract][Full Text] [Related]
13. [Effect of Glycyrrhiza inflata and Daphne genkwa on permeabilities of rhodamine 123, a P-glycoprotein substrate across rat jejunum membranes in vitro].
Huang BB; Li GF; Ren F; Tang ZK; Ma HF; Sun YB; Chen LJ; Yang L
Zhongguo Zhong Yao Za Zhi; 2008 Nov; 33(21):2521-6. PubMed ID: 19149264
[TBL] [Abstract][Full Text] [Related]
14. Effect of P-glycoprotein on intestinal absorption and brain penetration of antiallergic agent bepotastine besilate.
Ohashi R; Kamikozawa Y; Sugiura M; Fukuda H; Yabuuchi H; Tamai I
Drug Metab Dispos; 2006 May; 34(5):793-9. PubMed ID: 16455807
[TBL] [Abstract][Full Text] [Related]
15. Modulation of the permeability of H2 receptor antagonists cimetidine and ranitidine by P-glycoprotein in rat intestine and the human colonic cell line Caco-2.
Collett A; Higgs NB; Sims E; Rowland M; Warhurst G
J Pharmacol Exp Ther; 1999 Jan; 288(1):171-8. PubMed ID: 9862768
[TBL] [Abstract][Full Text] [Related]
16. Evaluation of the permeability and P-glycoprotein efflux of carbamazepine and several derivatives across mouse small intestine by the Ussing chamber technique.
Fortuna A; Alves G; Falcão A; Soares-da-Silva P
Epilepsia; 2012 Mar; 53(3):529-38. PubMed ID: 22372629
[TBL] [Abstract][Full Text] [Related]
17. Increased plasma exposures of five protoberberine alkaloids from Coptidis Rhizoma in streptozotocin-induced diabetic rats: is P-GP involved?
Yu S; Yu Y; Liu L; Wang X; Lu S; Liang Y; Liu X; Xie L; Wang G
Planta Med; 2010 Jun; 76(9):876-81. PubMed ID: 20108175
[TBL] [Abstract][Full Text] [Related]
18. Study on in situ and in vivo absorption kinetics of phenytoin by modulating P-glycoprotein with verapamil in rats.
Neerati P; Ganji D; Bedada SK
Eur J Pharm Sci; 2011 Sep; 44(1-2):27-31. PubMed ID: 21640186
[TBL] [Abstract][Full Text] [Related]
19. Circadian variations in exsorptive transport: in situ intestinal perfusion data and in vivo relevance.
Okyar A; Dressler C; Hanafy A; Baktir G; Lemmer B; Spahn-Langguth H
Chronobiol Int; 2012 May; 29(4):443-53. PubMed ID: 22489638
[TBL] [Abstract][Full Text] [Related]
20. Up-regulation of P-glycoprotein expression in small intestine under chronic serotonin-depleted conditions in rats.
Hiraoka H; Kimura N; Furukawa Y; Ogawara K; Kimura T; Higaki K
J Pharmacol Exp Ther; 2005 Jan; 312(1):248-55. PubMed ID: 15466248
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
