BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

295 related articles for article (PubMed ID: 18278854)

  • 1. Conversion of a highly selective sigma-1 receptor-ligand to sigma-2 receptor preferring ligands with anticocaine activity.
    Mésangeau C; Narayanan S; Green AM; Shaikh J; Kaushal N; Viard E; Xu YT; Fishback JA; Poupaert JH; Matsumoto RR; McCurdy CR
    J Med Chem; 2008 Mar; 51(5):1482-6. PubMed ID: 18278854
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Structure-activity comparison of YZ-069, a novel sigma ligand, and four analogs in receptor binding and behavioral studies.
    Matsumoto RR; Potelleret FH; Mack A; Pouw B; Zhang Y; Bowen WD
    Pharmacol Biochem Behav; 2004 Apr; 77(4):775-81. PubMed ID: 15099923
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Characterization of novel N,N'-disubstituted piperazines as sigma receptor ligands.
    Zhang Y; Williams W; Torrence-Campbell C; Bowen WD; Rice KC
    J Med Chem; 1998 Dec; 41(25):4950-7. PubMed ID: 9836612
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Dual probes for the dopamine transporter and sigma1 receptors: novel piperazinyl alkyl-bis(4'-fluorophenyl)amine analogues as potential cocaine-abuse therapeutic agents.
    Cao J; Kulkarni SS; Husbands SM; Bowen WD; Williams W; Kopajtic T; Katz JL; George C; Newman AH
    J Med Chem; 2003 Jun; 46(13):2589-98. PubMed ID: 12801223
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Synthesis and anticonvulsant activity of 2(3H)-benzoxazolone and 2(3H)-benzothiazolone derivatives.
    Ucar H; Van derpoorten K; Cacciaguerra S; Spampinato S; Stables JP; Depovere P; Isa M; Masereel B; Delarge J; Poupaert JH
    J Med Chem; 1998 Mar; 41(7):1138-45. PubMed ID: 9544213
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Effects of the selective sigma receptor ligand, 6-[6-(4-hydroxypiperidinyl)hexyloxy]-3-methylflavone (NPC 16377), on behavioral and toxic effects of cocaine.
    Witkin JM; Terry P; Menkel M; Hickey P; Pontecorvo M; Ferkany J; Katz JL
    J Pharmacol Exp Ther; 1993 Aug; 266(2):473-82. PubMed ID: 8355185
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Effect of sigma ligands on the cocaine-induced convulsions in mice.
    Skuza G
    Pol J Pharmacol; 1999; 51(6):477-83. PubMed ID: 10817525
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Novel analogs of the sigma receptor ligand BD1008 attenuate cocaine-induced toxicity in mice.
    Matsumoto RR; Gilmore DL; Pouw B; Bowen WD; Williams W; Kausar A; Coop A
    Eur J Pharmacol; 2004 May; 492(1):21-6. PubMed ID: 15145701
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Synthesis and structure-activity relationships of N-(3-phenylpropyl)-N'-benzylpiperazines: Potent ligands for sigma1 and sigma2 receptors.
    Nahas RI; Lever JR; Lever SZ
    Bioorg Med Chem; 2008 Jan; 16(2):755-61. PubMed ID: 18029187
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Effects of linker elongation in a series of N-(2-benzofuranylmethyl)-N'-(methoxyphenylalkyl)piperazine σ₁ receptor ligands.
    Moussa IA; Banister SD; Akladios FN; Chua SW; Kassiou M
    Bioorg Med Chem Lett; 2011 Oct; 21(19):5707-10. PubMed ID: 21871797
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Exploring the importance of piperazine N-atoms for sigma(2) receptor affinity and activity in a series of analogs of 1-cyclohexyl-4-[3-(5-methoxy-1,2,3,4-tetrahydronaphthalen-1-yl)propyl]piperazine (PB28).
    Berardi F; Abate C; Ferorelli S; Uricchio V; Colabufo NA; Niso M; Perrone R
    J Med Chem; 2009 Dec; 52(23):7817-28. PubMed ID: 19842660
    [TBL] [Abstract][Full Text] [Related]  

  • 12. 4-(tetralin-1-yl)- and 4-(naphthalen-1-yl)alkyl derivatives of 1-cyclohexylpiperazine as sigma receptor ligands with agonist sigma2 activity.
    Berardi F; Ferorelli S; Abate C; Colabufo NA; Contino M; Perrone R; Tortorella V
    J Med Chem; 2004 Apr; 47(9):2308-17. PubMed ID: 15084129
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Rimcazole analogs attenuate the convulsive effects of cocaine: correlation with binding to sigma receptors rather than dopamine transporters.
    Matsumoto RR; Hewett KL; Pouw B; Bowen WD; Husbands SM; Cao JJ; Newman AH
    Neuropharmacology; 2001 Dec; 41(7):878-86. PubMed ID: 11684152
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Synthesis and structure-activity relationships of 1-aralkyl-4-benzylpiperidine and 1-aralkyl-4-benzylpiperazine derivatives as potent sigma ligands.
    Costantino L; Gandolfi F; Sorbi C; Franchini S; Prezzavento O; Vittorio F; Ronsisvalle G; Leonardi A; Poggesi E; Brasili L
    J Med Chem; 2005 Jan; 48(1):266-73. PubMed ID: 15634021
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Design, synthesis, structure-activity relationships, and biological characterization of novel arylalkoxyphenylalkylamine sigma ligands as potential antipsychotic drugs.
    Nakazato A; Ohta K; Sekiguchi Y; Okuyama S; Chaki S; Kawashima Y; Hatayama K
    J Med Chem; 1999 Mar; 42(6):1076-87. PubMed ID: 10090790
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Benzimidazolone-based selective σ
    Intagliata S; Alsharif WF; Mesangeau C; Fazio N; Seminerio M; Xu YT; Matsumoto RR; McCurdy CR
    Eur J Med Chem; 2019 Mar; 165():250-257. PubMed ID: 30685525
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Synthesis of bridged piperazines with sigma receptor affinity.
    Weigl M; Wünsch B
    Eur J Med Chem; 2007 Oct; 42(10):1247-62. PubMed ID: 17420073
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Phenytoin differentially modulates the affinity of agonist and antagonist ligands for sigma 1 receptors of guinea pig brain.
    Cobos EJ; Baeyens JM; Del Pozo E
    Synapse; 2005 Mar; 55(3):192-5. PubMed ID: 15635593
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Effects of N-phenylpropyl-N'-substituted piperazine sigma receptor ligands on cocaine-induced hyperactivity in mice.
    Sage AS; Oelrichs CE; Davis DC; Fan KH; Nahas RI; Lever SZ; Lever JR; Miller DK
    Pharmacol Biochem Behav; 2013 Sep; 110():201-7. PubMed ID: 23891829
    [TBL] [Abstract][Full Text] [Related]  

  • 20. alpha 2-adrenoreceptors profile modulation. 2. Biphenyline analogues as tools for selective activation of the alpha 2C-subtype.
    Gentili F; Ghelfi F; Giannella M; Piergentili A; Pigini M; Quaglia W; Vesprini C; Crassous PA; Paris H; Carrieri A
    J Med Chem; 2004 Dec; 47(25):6160-73. PubMed ID: 15566287
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 15.