BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

186 related articles for article (PubMed ID: 18281382)

  • 1. Myofilament mechanical performance is enhanced by R403Q myosin in mouse myocardium independent of sex.
    Palmer BM; Wang Y; Teekakirikul P; Hinson JT; Fatkin D; Strouse S; Vanburen P; Seidman CE; Seidman JG; Maughan DW
    Am J Physiol Heart Circ Physiol; 2008 Apr; 294(4):H1939-47. PubMed ID: 18281382
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Differential cross-bridge kinetics of FHC myosin mutations R403Q and R453C in heterozygous mouse myocardium.
    Palmer BM; Fishbaugher DE; Schmitt JP; Wang Y; Alpert NR; Seidman CE; Seidman JG; VanBuren P; Maughan DW
    Am J Physiol Heart Circ Physiol; 2004 Jul; 287(1):H91-9. PubMed ID: 15001446
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Functional effects of the hypertrophic cardiomyopathy R403Q mutation are different in an alpha- or beta-myosin heavy chain backbone.
    Lowey S; Lesko LM; Rovner AS; Hodges AR; White SL; Low RB; Rincon M; Gulick J; Robbins J
    J Biol Chem; 2008 Jul; 283(29):20579-89. PubMed ID: 18480046
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Hypertrophic cardiomyopathy R403Q mutation in rabbit β-myosin reduces contractile function at the molecular and myofibrillar levels.
    Lowey S; Bretton V; Joel PB; Trybus KM; Gulick J; Robbins J; Kalganov A; Cornachione AS; Rassier DE
    Proc Natl Acad Sci U S A; 2018 Oct; 115(44):11238-11243. PubMed ID: 30322937
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Altered crossbridge kinetics in the alphaMHC403/+ mouse model of familial hypertrophic cardiomyopathy.
    Blanchard E; Seidman C; Seidman JG; LeWinter M; Maughan D
    Circ Res; 1999 Mar; 84(4):475-83. PubMed ID: 10066683
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Fropofol prevents disease progression in mice with hypertrophic cardiomyopathy.
    Huang Y; Lu H; Ren X; Li F; Bu W; Liu W; Dailey WP; Saeki H; Gabrielson K; Abraham R; Eckenhoff R; Gao WD
    Cardiovasc Res; 2020 May; 116(6):1175-1185. PubMed ID: 31424496
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Sexually dimorphic myofilament function and cardiac troponin I phosphospecies distribution in hypertrophic cardiomyopathy mice.
    McKee LA; Chen H; Regan JA; Behunin SM; Walker JW; Walker JS; Konhilas JP
    Arch Biochem Biophys; 2013 Jul; 535(1):39-48. PubMed ID: 23352598
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Faster cross-bridge detachment and increased tension cost in human hypertrophic cardiomyopathy with the R403Q MYH7 mutation.
    Witjas-Paalberends ER; Ferrara C; Scellini B; Piroddi N; Montag J; Tesi C; Stienen GJ; Michels M; Ho CY; Kraft T; Poggesi C; van der Velden J
    J Physiol; 2014 Aug; 592(15):3257-72. PubMed ID: 24928957
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Cardiac transgenesis with the tetracycline transactivator changes myocardial function and gene expression.
    McCloskey DT; Turnbull L; Swigart PM; Zambon AC; Turcato S; Joho S; Grossman W; Conklin BR; Simpson PC; Baker AJ
    Physiol Genomics; 2005 Jun; 22(1):118-26. PubMed ID: 15797971
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Transgenic mouse α- and β-cardiac myosins containing the R403Q mutation show isoform-dependent transient kinetic differences.
    Lowey S; Bretton V; Gulick J; Robbins J; Trybus KM
    J Biol Chem; 2013 May; 288(21):14780-7. PubMed ID: 23580644
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Perturbed length-dependent activation in human hypertrophic cardiomyopathy with missense sarcomeric gene mutations.
    Sequeira V; Wijnker PJ; Nijenkamp LL; Kuster DW; Najafi A; Witjas-Paalberends ER; Regan JA; Boontje N; Ten Cate FJ; Germans T; Carrier L; Sadayappan S; van Slegtenhorst MA; Zaremba R; Foster DB; Murphy AM; Poggesi C; Dos Remedios C; Stienen GJ; Ho CY; Michels M; van der Velden J
    Circ Res; 2013 May; 112(11):1491-505. PubMed ID: 23508784
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Altered myocyte contractility and calcium homeostasis in alpha-myosin heavy chain point mutations linked to familial dilated cardiomyopathy.
    Klos M; Mundada L; Banerjee I; Morgenstern S; Myers S; Leone M; Kleid M; Herron T; Devaney E
    Arch Biochem Biophys; 2017 Feb; 615():53-60. PubMed ID: 28088328
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Hypertrophic and dilated cardiomyopathy mutations differentially affect the molecular force generation of mouse alpha-cardiac myosin in the laser trap assay.
    Debold EP; Schmitt JP; Patlak JB; Beck SE; Moore JR; Seidman JG; Seidman C; Warshaw DM
    Am J Physiol Heart Circ Physiol; 2007 Jul; 293(1):H284-91. PubMed ID: 17351073
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The effect of cardiomyopathy mutation (R97L) in mouse cardiac troponin T on the muscle length-mediated recruitment of crossbridges is modified divergently by α- and β-myosin heavy chain.
    Gollapudi SK; Chandra M
    Arch Biochem Biophys; 2016 Jul; 601():105-12. PubMed ID: 26792537
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Point mutations in human beta cardiac myosin heavy chain have differential effects on sarcomeric structure and assembly: an ATP binding site change disrupts both thick and thin filaments, whereas hypertrophic cardiomyopathy mutations display normal assembly.
    Becker KD; Gottshall KR; Hickey R; Perriard JC; Chien KR
    J Cell Biol; 1997 Apr; 137(1):131-40. PubMed ID: 9105042
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Early remodeling of repolarizing K
    Hueneke R; Adenwala A; Mellor RL; Seidman JG; Seidman CE; Nerbonne JM
    J Mol Cell Cardiol; 2017 Feb; 103():93-101. PubMed ID: 28089740
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Differences in molecular phenotype in mouse and human hypertrophic cardiomyopathy.
    Vakrou S; Liu Y; Zhu L; Greenland GV; Simsek B; Hebl VB; Guan Y; Woldemichael K; Talbot CC; Aon MA; Fukunaga R; Abraham MR
    Sci Rep; 2021 Jun; 11(1):13163. PubMed ID: 34162896
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The familial hypertrophic cardiomyopathy-associated myosin mutation R403Q accelerates tension generation and relaxation of human cardiac myofibrils.
    Belus A; Piroddi N; Scellini B; Tesi C; D'Amati G; Girolami F; Yacoub M; Cecchi F; Olivotto I; Poggesi C
    J Physiol; 2008 Aug; 586(15):3639-44. PubMed ID: 18565996
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Hypertrophic cardiomyopathy associated E22K mutation in myosin regulatory light chain decreases calcium-activated tension and stiffness and reduces myofilament Ca
    Zhang J; Wang L; Kazmierczak K; Yun H; Szczesna-Cordary D; Kawai M
    FEBS J; 2021 Aug; 288(15):4596-4613. PubMed ID: 33548158
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Structural and functional impact of troponin C-mediated Ca
    Gonzalez-Martinez D; Johnston JR; Landim-Vieira M; Ma W; Antipova O; Awan O; Irving TC; Bryant Chase P; Pinto JR
    J Mol Cell Cardiol; 2018 Oct; 123():26-37. PubMed ID: 30138628
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.