BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

216 related articles for article (PubMed ID: 18281595)

  • 1. Drug-induced alterations to gene and protein expression in intestinal epithelial cell 6 cells suggest a role for calpains in the gastrointestinal toxicity of nonsteroidal anti-inflammatory agents.
    Raveendran NN; Silver K; Freeman LC; Narvaez D; Weng K; Ganta S; Lillich JD
    J Pharmacol Exp Ther; 2008 May; 325(2):389-99. PubMed ID: 18281595
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Expression of pleiotrophin, an important regulator of cell migration, is inhibited in intestinal epithelial cells by treatment with non-steroidal anti-inflammatory drugs.
    Silver K; Desormaux A; Freeman LC; Lillich JD
    Growth Factors; 2012 Aug; 30(4):258-66. PubMed ID: 22691166
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Inhibition of Kv channel expression by NSAIDs depolarizes membrane potential and inhibits cell migration by disrupting calpain signaling.
    Silver K; Littlejohn A; Thomas L; Marsh E; Lillich JD
    Biochem Pharmacol; 2015 Dec; 98(4):614-28. PubMed ID: 26549367
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Suppression of calpain expression by NSAIDs is associated with inhibition of cell migration in rat duodenum.
    Silver K; Littlejohn A; Thomas L; Bawa B; Lillich JD
    Toxicology; 2017 May; 383():1-12. PubMed ID: 28342779
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Non-steroidal anti-inflammatory drugs inhibit calpain activity and membrane localization of calpain 2 protease.
    Silver K; Leloup L; Freeman LC; Wells A; Lillich JD
    Int J Biochem Cell Biol; 2010 Dec; 42(12):2030-6. PubMed ID: 20854926
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Inhibition of human telomerase reverse transcriptase by nonsteroidal antiinflammatory drugs in colon carcinoma.
    He H; Xia HH; Wang JD; Gu Q; Lin MC; Zou B; Lam SK; Chan AO; Yuen MF; Kung HF; Wong BC
    Cancer; 2006 Mar; 106(6):1243-9. PubMed ID: 16444744
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Induction of claudin-4 by nonsteroidal anti-inflammatory drugs and its contribution to their chemopreventive effect.
    Mima S; Tsutsumi S; Ushijima H; Takeda M; Fukuda I; Yokomizo K; Suzuki K; Sano K; Nakanishi T; Tomisato W; Tsuchiya T; Mizushima T
    Cancer Res; 2005 Mar; 65(5):1868-76. PubMed ID: 15753385
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Enhancement of doxorubicin cytotoxicity on human esophageal squamous cell carcinoma cells by indomethacin and 4-[5-(4-chlorophenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]benzenesulfonamide (SC236) via inhibiting P-glycoprotein activity.
    Yu L; Wu WK; Li ZJ; Liu QC; Li HT; Wu YC; Cho CH
    Mol Pharmacol; 2009 Jun; 75(6):1364-73. PubMed ID: 19264847
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Vascular endothelial growth factor (VEGF164) ameliorates intestinal epithelial injury in vitro in IEC-18 and Caco-2 monolayers via induction of TGF-beta release from epithelial cells.
    Bulut K; Pennartz C; Felderbauer P; Ansorge N; Banasch M; Schmitz F; Schmidt WE; Hoffmann P
    Scand J Gastroenterol; 2006 Jun; 41(6):687-92. PubMed ID: 16716967
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Pattern recognition analysis for the prediction of adverse effects by nonsteroidal anti-inflammatory drugs using 1H NMR-based metabolomics in rats.
    Um SY; Chung MW; Kim KB; Kim SH; Oh JS; Oh HY; Lee HJ; Choi KH
    Anal Chem; 2009 Jun; 81(12):4734-41. PubMed ID: 19462990
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Nonsteroidal antiinflammatory drugs and a selective cyclooxygenase 2 inhibitor uncouple mitochondria in intact cells.
    Krause MM; Brand MD; Krauss S; Meisel C; Vergin H; Burmester GR; Buttgereit F
    Arthritis Rheum; 2003 May; 48(5):1438-44. PubMed ID: 12746918
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Depolarization and decreased surface expression of K+ channels contribute to NSAID-inhibition of intestinal restitution.
    Freeman LC; Narvaez DF; McCoy A; von Stein FB; Young S; Silver K; Ganta S; Koch D; Hunter R; Gilmour RF; Lillich JD
    Biochem Pharmacol; 2007 Jun; 74(1):74-85. PubMed ID: 17499219
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Differential effects of COX inhibitors against beta-amyloid-induced neurotoxicity in human neuroblastoma cells.
    Ferrera P; Arias C
    Neurochem Int; 2005 Dec; 47(8):589-96. PubMed ID: 16169124
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Inhibition of both COX-1 and COX-2 and resulting decrease in the level of prostaglandins E2 is responsible for non-steroidal anti-inflammatory drug (NSAID)-dependent exacerbation of colitis.
    Tanaka K; Suemasu S; Ishihara T; Tasaka Y; Arai Y; Mizushima T
    Eur J Pharmacol; 2009 Jan; 603(1-3):120-32. PubMed ID: 19101538
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Multiple defects in negative regulation of the PKB/Akt pathway sensitise human cancer cells to the antiproliferative effect of non-steroidal anti-inflammatory drugs.
    Lincová E; Hampl A; Pernicová Z; Starsíchová A; Krcmár P; Machala M; Kozubík A; Soucek K
    Biochem Pharmacol; 2009 Sep; 78(6):561-72. PubMed ID: 19433066
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Induction of RECK by nonsteroidal anti-inflammatory drugs in lung cancer cells.
    Liu LT; Chang HC; Chiang LC; Hung WC
    Oncogene; 2002 Nov; 21(54):8347-50. PubMed ID: 12447698
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Intestinal effects of nonselective and selective cyclooxygenase inhibitors in the rat.
    Menozzi A; Pozzoli C; Giovannini E; Solenghi E; Grandi D; Bonardi S; Bertini S; Vasina V; Coruzzi G
    Eur J Pharmacol; 2006 Dec; 552(1-3):143-50. PubMed ID: 17069793
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Stromal cell-derived factor 1 (SDF-1, CXCL12) is increased in subacromial bursitis and downregulated by steroid and nonsteroidal anti-inflammatory agents.
    Kim YS; Bigliani LU; Fujisawa M; Murakami K; Chang SS; Lee HJ; Lee FY; Blaine TA
    J Orthop Res; 2006 Aug; 24(8):1756-64. PubMed ID: 16779827
    [TBL] [Abstract][Full Text] [Related]  

  • 19. NSAIDs suppress the expression of claudin-2 to promote invasion activity of cancer cells.
    Mima S; Takehara M; Takada H; Nishimura T; Hoshino T; Mizushima T
    Carcinogenesis; 2008 Oct; 29(10):1994-2000. PubMed ID: 18586689
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Nonsteroidal anti-inflammatory drugs potentiate 1-methyl-4-phenylpyridinium (MPP+)-induced cell death by promoting the intracellular accumulation of MPP+ in PC12 cells.
    Morioka N; Kumagai K; Morita K; Kitayama S; Dohi T
    J Pharmacol Exp Ther; 2004 Aug; 310(2):800-7. PubMed ID: 15131242
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.