BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

443 related articles for article (PubMed ID: 18281698)

  • 1. LARP7 is a stable component of the 7SK snRNP while P-TEFb, HEXIM1 and hnRNP A1 are reversibly associated.
    Krueger BJ; Jeronimo C; Roy BB; Bouchard A; Barrandon C; Byers SA; Searcey CE; Cooper JJ; Bensaude O; Cohen EA; Coulombe B; Price DH
    Nucleic Acids Res; 2008 Apr; 36(7):2219-29. PubMed ID: 18281698
    [TBL] [Abstract][Full Text] [Related]  

  • 2. RNA elements directing in vivo assembly of the 7SK/MePCE/Larp7 transcriptional regulatory snRNP.
    Muniz L; Egloff S; Kiss T
    Nucleic Acids Res; 2013 Apr; 41(8):4686-98. PubMed ID: 23471002
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The mechanism of release of P-TEFb and HEXIM1 from the 7SK snRNP by viral and cellular activators includes a conformational change in 7SK.
    Krueger BJ; Varzavand K; Cooper JJ; Price DH
    PLoS One; 2010 Aug; 5(8):e12335. PubMed ID: 20808803
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Release of positive transcription elongation factor b (P-TEFb) from 7SK small nuclear ribonucleoprotein (snRNP) activates hexamethylene bisacetamide-inducible protein (HEXIM1) transcription.
    Liu P; Xiang Y; Fujinaga K; Bartholomeeusen K; Nilson KA; Price DH; Peterlin BM
    J Biol Chem; 2014 Apr; 289(14):9918-25. PubMed ID: 24515107
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Genetic analysis of the structure and function of 7SK small nuclear ribonucleoprotein (snRNP) in cells.
    Fujinaga K; Luo Z; Peterlin BM
    J Biol Chem; 2014 Jul; 289(30):21181-90. PubMed ID: 24917669
    [TBL] [Abstract][Full Text] [Related]  

  • 6. A capping-independent function of MePCE in stabilizing 7SK snRNA and facilitating the assembly of 7SK snRNP.
    Xue Y; Yang Z; Chen R; Zhou Q
    Nucleic Acids Res; 2010 Jan; 38(2):360-9. PubMed ID: 19906723
    [TBL] [Abstract][Full Text] [Related]  

  • 7. PPM1G Binds 7SK RNA and Hexim1 To Block P-TEFb Assembly into the 7SK snRNP and Sustain Transcription Elongation.
    Gudipaty SA; McNamara RP; Morton EL; D'Orso I
    Mol Cell Biol; 2015 Nov; 35(22):3810-28. PubMed ID: 26324325
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Dynamic remodelling of human 7SK snRNP controls the nuclear level of active P-TEFb.
    Van Herreweghe E; Egloff S; Goiffon I; Jády BE; Froment C; Monsarrat B; Kiss T
    EMBO J; 2007 Aug; 26(15):3570-80. PubMed ID: 17611602
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Phosphorylation of HEXIM1 at Tyr271 and Tyr274 Promotes Release of P-TEFb from the 7SK snRNP Complex and Enhances Proviral HIV Gene Expression.
    Mbonye UR; Wang B; Gokulrangan G; Chance MR; Karn J
    Proteomics; 2015 Jun; 15(12):2078-86. PubMed ID: 25900325
    [TBL] [Abstract][Full Text] [Related]  

  • 10. de novo MEPCE nonsense variant associated with a neurodevelopmental disorder causes disintegration of 7SK snRNP and enhanced RNA polymerase II activation.
    Schneeberger PE; Bierhals T; Neu A; Hempel M; Kutsche K
    Sci Rep; 2019 Aug; 9(1):12516. PubMed ID: 31467394
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Bromodomain and extra-terminal (BET) bromodomain inhibition activate transcription via transient release of positive transcription elongation factor b (P-TEFb) from 7SK small nuclear ribonucleoprotein.
    Bartholomeeusen K; Xiang Y; Fujinaga K; Peterlin BM
    J Biol Chem; 2012 Oct; 287(43):36609-16. PubMed ID: 22952229
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The La-related protein LARP7 is a component of the 7SK ribonucleoprotein and affects transcription of cellular and viral polymerase II genes.
    Markert A; Grimm M; Martinez J; Wiesner J; Meyerhans A; Meyuhas O; Sickmann A; Fischer U
    EMBO Rep; 2008 Jun; 9(6):569-75. PubMed ID: 18483487
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Controlling cellular P-TEFb activity by the HIV-1 transcriptional transactivator Tat.
    Muniz L; Egloff S; Ughy B; Jády BE; Kiss T
    PLoS Pathog; 2010 Oct; 6(10):e1001152. PubMed ID: 20976203
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The transcription-dependent dissociation of P-TEFb-HEXIM1-7SK RNA relies upon formation of hnRNP-7SK RNA complexes.
    Barrandon C; Bonnet F; Nguyen VT; Labas V; Bensaude O
    Mol Cell Biol; 2007 Oct; 27(20):6996-7006. PubMed ID: 17709395
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Analysis of the large inactive P-TEFb complex indicates that it contains one 7SK molecule, a dimer of HEXIM1 or HEXIM2, and two P-TEFb molecules containing Cdk9 phosphorylated at threonine 186.
    Li Q; Price JP; Byers SA; Cheng D; Peng J; Price DH
    J Biol Chem; 2005 Aug; 280(31):28819-26. PubMed ID: 15965233
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Manipulation of P-TEFb control machinery by HIV: recruitment of P-TEFb from the large form by Tat and binding of HEXIM1 to TAR.
    Sedore SC; Byers SA; Biglione S; Price JP; Maury WJ; Price DH
    Nucleic Acids Res; 2007; 35(13):4347-58. PubMed ID: 17576689
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Tat competes with HEXIM1 to increase the active pool of P-TEFb for HIV-1 transcription.
    Barboric M; Yik JH; Czudnochowski N; Yang Z; Chen R; Contreras X; Geyer M; Matija Peterlin B; Zhou Q
    Nucleic Acids Res; 2007; 35(6):2003-12. PubMed ID: 17341462
    [TBL] [Abstract][Full Text] [Related]  

  • 18. LARP7 suppresses P-TEFb activity to inhibit breast cancer progression and metastasis.
    Ji X; Lu H; Zhou Q; Luo K
    Elife; 2014 Jul; 3():e02907. PubMed ID: 25053741
    [TBL] [Abstract][Full Text] [Related]  

  • 19. An alternative D. melanogaster 7SK snRNP.
    Nguyen D; Buisine N; Fayol O; Michels AA; Bensaude O; Price DH; Uguen P
    BMC Mol Cell Biol; 2021 Aug; 22(1):43. PubMed ID: 34461828
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The Drosophila 7SK snRNP and the essential role of dHEXIM in development.
    Nguyen D; Krueger BJ; Sedore SC; Brogie JE; Rogers JT; Rajendra TK; Saunders A; Matera AG; Lis JT; Uguen P; Price DH
    Nucleic Acids Res; 2012 Jul; 40(12):5283-97. PubMed ID: 22379134
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 23.