BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

335 related articles for article (PubMed ID: 18282486)

  • 1. Structural genomics and drug discovery: all in the family.
    Weigelt J; McBroom-Cerajewski LD; Schapira M; Zhao Y; Arrowsmith CH
    Curr Opin Chem Biol; 2008 Feb; 12(1):32-9. PubMed ID: 18282486
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Doing more than just the structure-structural genomics in kinase drug discovery.
    Marsden BD; Knapp S
    Curr Opin Chem Biol; 2008 Feb; 12(1):40-5. PubMed ID: 18267130
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Structural genomics-impact on biomedicine and drug discovery.
    Weigelt J
    Exp Cell Res; 2010 May; 316(8):1332-8. PubMed ID: 20211166
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Predicting protein druggability.
    Hajduk PJ; Huth JR; Tse C
    Drug Discov Today; 2005 Dec; 10(23-24):1675-82. PubMed ID: 16376828
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Making drugs on proteins: site-directed ligand discovery for fragment-based lead assembly.
    Erlanson DA; Hansen SK
    Curr Opin Chem Biol; 2004 Aug; 8(4):399-406. PubMed ID: 15288250
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Form follows function: shape analysis of protein cavities for receptor-based drug design.
    Weisel M; Proschak E; Kriegl JM; Schneider G
    Proteomics; 2009 Jan; 9(2):451-9. PubMed ID: 19142949
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The use of protein-ligand interaction fingerprints in docking.
    Brewerton SC
    Curr Opin Drug Discov Devel; 2008 May; 11(3):356-64. PubMed ID: 18428089
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Exploring functional genomics for drug target and therapeutics discovery in Plasmodia.
    Birkholtz L; van Brummelen AC; Clark K; Niemand J; Maréchal E; Llinás M; Louw AI
    Acta Trop; 2008 Feb; 105(2):113-23. PubMed ID: 18083131
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Proteomic methods for drug target discovery.
    Sleno L; Emili A
    Curr Opin Chem Biol; 2008 Feb; 12(1):46-54. PubMed ID: 18282485
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Structural diversity of G protein-coupled receptors and significance for drug discovery.
    Lagerström MC; Schiöth HB
    Nat Rev Drug Discov; 2008 Apr; 7(4):339-57. PubMed ID: 18382464
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Insights for the development of specific kinase inhibitors by targeted structural genomics.
    Fedorov O; Sundström M; Marsden B; Knapp S
    Drug Discov Today; 2007 May; 12(9-10):365-72. PubMed ID: 17467572
    [TBL] [Abstract][Full Text] [Related]  

  • 12. PDBLIG: classification of small molecular protein binding in the Protein Data Bank.
    Chalk AJ; Worth CL; Overington JP; Chan AW
    J Med Chem; 2004 Jul; 47(15):3807-16. PubMed ID: 15239659
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Chemogenomics: structuring the drug discovery process to gene families.
    Harris CJ; Stevens AP
    Drug Discov Today; 2006 Oct; 11(19-20):880-8. PubMed ID: 16997137
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The ATCG of drug discovery.
    Fernandes PB
    Curr Opin Mol Ther; 2000 Dec; 2(6):624-32. PubMed ID: 11249739
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Applications of ESI-MS in drug discovery: interrogation of noncovalent complexes.
    Hofstadler SA; Sannes-Lowery KA
    Nat Rev Drug Discov; 2006 Jul; 5(7):585-95. PubMed ID: 16816839
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Structural proteomics in drug discovery.
    Tari LW; Rosenberg M; Schryvers AB
    Expert Rev Proteomics; 2005 Aug; 2(4):511-9. PubMed ID: 16097885
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Screening for transient biological interactions as applied to albumin ligands: a new concept for drug discovery.
    Ohlson S; Shoravi S; Fex T; Isaksson R
    Anal Biochem; 2006 Dec; 359(1):120-3. PubMed ID: 17052679
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Protein-protein interactions as targets for small molecule drug discovery.
    Fry DC
    Biopolymers; 2006; 84(6):535-52. PubMed ID: 17009316
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The modular approach to ligand discovery.
    Karan C; Tallarico JA
    Chem Biol; 2004 Mar; 11(3):292-3. PubMed ID: 15123257
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Predicting druggable binding sites at the protein-protein interface.
    Fuller JC; Burgoyne NJ; Jackson RM
    Drug Discov Today; 2009 Feb; 14(3-4):155-61. PubMed ID: 19041415
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 17.