These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
772 related articles for article (PubMed ID: 18283461)
1. Dynamics of antifolate transport via the reduced folate carrier and the membrane folate receptor in murine leukaemia cells in vitro and in vivo. Mauritz R; Peters GJ; Kathmann I; Teshale H; Noordhuis P; Comijn EM; Pinedo HM; Jansen G Cancer Chemother Pharmacol; 2008 Nov; 62(6):937-48. PubMed ID: 18283461 [TBL] [Abstract][Full Text] [Related]
2. Carrier- and receptor-mediated transport of folate antagonists targeting folate-dependent enzymes: correlates of molecular-structure and biological activity. Westerhof GR; Schornagel JH; Kathmann I; Jackman AL; Rosowsky A; Forsch RA; Hynes JB; Boyle FT; Peters GJ; Pinedo HM Mol Pharmacol; 1995 Sep; 48(3):459-71. PubMed ID: 7565626 [TBL] [Abstract][Full Text] [Related]
3. Membrane transport of natural folates and antifolate compounds in murine L1210 leukemia cells: role of carrier- and receptor-mediated transport systems. Westerhof GR; Jansen G; van Emmerik N; Kathmann I; Rijksen G; Jackman AL; Schornagel JH Cancer Res; 1991 Oct; 51(20):5507-13. PubMed ID: 1655252 [TBL] [Abstract][Full Text] [Related]
4. ICI D1694, a quinazoline antifolate thymidylate synthase inhibitor that is a potent inhibitor of L1210 tumor cell growth in vitro and in vivo: a new agent for clinical study. Jackman AL; Taylor GA; Gibson W; Kimbell R; Brown M; Calvert AH; Judson IR; Hughes LR Cancer Res; 1991 Oct; 51(20):5579-86. PubMed ID: 1913676 [TBL] [Abstract][Full Text] [Related]
5. 5-amino-4-imidazolecarboxamide riboside potentiates both transport of reduced folates and antifolates by the human reduced folate carrier and their subsequent metabolism. McGuire JJ; Haile WH; Yeh CC Cancer Res; 2006 Apr; 66(7):3836-44. PubMed ID: 16585211 [TBL] [Abstract][Full Text] [Related]
6. The mechanism of transport of the multitargeted antifolate (MTA) and its cross-resistance pattern in cells with markedly impaired transport of methotrexate. Zhao R; Babani S; Gao F; Liu L; Goldman ID Clin Cancer Res; 2000 Sep; 6(9):3687-95. PubMed ID: 10999762 [TBL] [Abstract][Full Text] [Related]
7. BGC 945, a novel tumor-selective thymidylate synthase inhibitor targeted to alpha-folate receptor-overexpressing tumors. Gibbs DD; Theti DS; Wood N; Green M; Raynaud F; Valenti M; Forster MD; Mitchell F; Bavetsias V; Henderson E; Jackman AL Cancer Res; 2005 Dec; 65(24):11721-8. PubMed ID: 16357184 [TBL] [Abstract][Full Text] [Related]
8. Functional aspects of membrane folate receptors in human breast cancer cells with transport-related resistance to methotrexate. Pinard MF; Jolivet J; Ratnam M; Kathmann I; Molthoff C; Westerhof R; Schornagel JH; Jansen G Cancer Chemother Pharmacol; 1996; 38(3):281-8. PubMed ID: 8646804 [TBL] [Abstract][Full Text] [Related]
9. Activity of the thymidylate synthase inhibitor 2-desamino-N10-propargyl-5,8-dideazafolic acid and related compounds in murine (L1210) and human (W1L2) systems in vitro and in L1210 in vivo. Jackman AL; Taylor GA; O'Connor BM; Bishop JA; Moran RG; Calvert AH Cancer Res; 1990 Sep; 50(17):5212-8. PubMed ID: 2386929 [TBL] [Abstract][Full Text] [Related]
10. Characterization of a folate transporter in HeLa cells with a low pH optimum and high affinity for pemetrexed distinct from the reduced folate carrier. Wang Y; Zhao R; Goldman ID Clin Cancer Res; 2004 Sep; 10(18 Pt 1):6256-64. PubMed ID: 15448015 [TBL] [Abstract][Full Text] [Related]
11. Determinants of activity of the antifolate thymidylate synthase inhibitors Tomudex (ZD1694) and GW1843U89 against mono- and multilayered colon cancer cell lines under folate-restricted conditions. Peters GJ; Smitskamp-Wilms E; Smid K; Pinedo HM; Jansen G Cancer Res; 1999 Nov; 59(21):5529-35. PubMed ID: 10554030 [TBL] [Abstract][Full Text] [Related]
12. Modulation of both endogenous folates and thymidine enhance the therapeutic efficacy of thymidylate synthase inhibitors. van der Wilt CL; Backus HH; Smid K; Comijn L; Veerman G; Wouters D; Voorn DA; Priest DG; Bunni MA; Mitchell F; Jackman AL; Jansen G; Peters GJ Cancer Res; 2001 May; 61(9):3675-81. PubMed ID: 11325838 [TBL] [Abstract][Full Text] [Related]
13. Ex vivo activity of methotrexate versus novel antifolate inhibitors of dihydrofolate reductase and thymidylate synthase against childhood leukemia cells. Mauritz R; Bekkenk MW; Rots MG; Pieters R; Mini E; van Zantwijk CH; Veerman AJ; Peters GJ; Jansen G Clin Cancer Res; 1998 Oct; 4(10):2399-410. PubMed ID: 9796971 [TBL] [Abstract][Full Text] [Related]
14. Antifolate resistance in a HeLa cell line associated with impaired transport independent of the reduced folate carrier. Zhao R; Chattopadhyay S; Hanscom M; Goldman ID Clin Cancer Res; 2004 Dec; 10(24):8735-42. PubMed ID: 15623659 [TBL] [Abstract][Full Text] [Related]
15. Multiple mechanisms of resistance to methotrexate and novel antifolates in human CCRF-CEM leukemia cells and their implications for folate homeostasis. Mauritz R; Peters GJ; Priest DG; Assaraf YG; Drori S; Kathmann I; Noordhuis P; Bunni MA; Rosowsky A; Schornagel JH; Pinedo HM; Jansen G Biochem Pharmacol; 2002 Jan; 63(2):105-15. PubMed ID: 11841783 [TBL] [Abstract][Full Text] [Related]
16. Quinazoline thymidylate synthase inhibitors: methods for assessing the contribution of polyglutamation to their in vitro activity. Jackman AL; Kimbell R; Brown M; Brunton L; Boyle FT Anticancer Drug Des; 1995 Oct; 10(7):555-72. PubMed ID: 7495479 [TBL] [Abstract][Full Text] [Related]
17. Functional activity of the reduced folate carrier in KB, MA104, and IGROV-I cells expressing folate-binding protein. Westerhof GR; Rijnboutt S; Schornagel JH; Pinedo HM; Peters GJ; Jansen G Cancer Res; 1995 Sep; 55(17):3795-802. PubMed ID: 7641196 [TBL] [Abstract][Full Text] [Related]
18. Cellular pharmacology and in vivo activity of a new anticancer agent, ZD9331: a water-soluble, nonpolyglutamatable, quinazoline-based inhibitor of thymidylate synthase. Jackman AL; Kimbell R; Aherne GW; Brunton L; Jansen G; Stephens TC; Smith MN; Wardleworth JM; Boyle FT Clin Cancer Res; 1997 Jun; 3(6):911-21. PubMed ID: 9815766 [TBL] [Abstract][Full Text] [Related]
19. Multiple membrane transport systems for the uptake of folate-based thymidylate synthase inhibitors. Jansen G; Schornagel JH; Westerhof GR; Rijksen G; Newell DR; Jackman AL Cancer Res; 1990 Dec; 50(23):7544-8. PubMed ID: 2253202 [TBL] [Abstract][Full Text] [Related]
20. Transport of the antitumor antibiotic Cl-920 into L1210 leukemia cells by the reduced folate carrier system. Fry DW; Besserer JA; Boritzki TJ Cancer Res; 1984 Aug; 44(8):3366-70. PubMed ID: 6547636 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]