BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

252 related articles for article (PubMed ID: 1828371)

  • 1. Single-chain urokinase-type plasminogen activator does not possess measurable intrinsic amidolytic or plasminogen activator activities.
    Husain SS
    Biochemistry; 1991 Jun; 30(23):5797-805. PubMed ID: 1828371
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Activation of plasminogen by single-chain urokinase or by two-chain urokinase--a demonstration that single-chain urokinase has a low catalytic activity (pro-urokinase).
    Pannell R; Gurewich V
    Blood; 1987 Jan; 69(1):22-6. PubMed ID: 3790724
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Structural and functional characterization of mutants of recombinant single-chain urokinase-type plasminogen activator obtained by site-specific mutagenesis of Lys158, Ile159 and Ile160.
    Lijnen HR; Nelles L; Van Hoef B; Demarsin E; Collen D
    Eur J Biochem; 1988 Nov; 177(3):575-82. PubMed ID: 2973984
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Characterization of the intrinsic fibrinolytic properties of pro-urokinase through a study of plasmin-resistant mutant forms produced by site-specific mutagenesis of lysine(158).
    Gurewich V; Pannell R; Broeze RJ; Mao J
    J Clin Invest; 1988 Dec; 82(6):1956-62. PubMed ID: 2974047
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Keratinocyte urokinase-type plasminogen activator is secreted as a single chain precursor.
    Hashimoto K; Prystowsky JH; Baird J; Lazarus GS; Jensen PJ
    J Invest Dermatol; 1988 Jun; 90(6):823-8. PubMed ID: 2967334
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Biochemical characterization of single-chain chimeric plasminogen activators consisting of a single-chain Fv fragment of a fibrin-specific antibody and single-chain urokinase.
    Holvoet P; Laroche Y; Lijnen HR; Van Hoef B; Brouwers E; De Cock F; Lauwereys M; Gansemans Y; Collen D
    Eur J Biochem; 1992 Dec; 210(3):945-52. PubMed ID: 1483477
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Accessibility of receptor-bound urokinase to type-1 plasminogen activator inhibitor.
    Cubellis MV; Andreasen P; Ragno P; Mayer M; Danø K; Blasi F
    Proc Natl Acad Sci U S A; 1989 Jul; 86(13):4828-32. PubMed ID: 2544876
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Biochemical properties of recombinant single-chain urokinase-type plasminogen activator mutants with deletion of Asn2 through Phe157 and/or substitution of Cys279 with Ala.
    Lijnen HR; Li XK; Nelles L; Hu MH; Collen D
    Eur J Biochem; 1992 Apr; 205(2):701-9. PubMed ID: 1533368
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Cathepsin B efficiently activates the soluble and the tumor cell receptor-bound form of the proenzyme urokinase-type plasminogen activator (Pro-uPA).
    Kobayashi H; Schmitt M; Goretzki L; Chucholowski N; Calvete J; Kramer M; Günzler WA; Jänicke F; Graeff H
    J Biol Chem; 1991 Mar; 266(8):5147-52. PubMed ID: 1900515
    [TBL] [Abstract][Full Text] [Related]  

  • 10. A transitional state of pro-urokinase that has a higher catalytic efficiency against glu-plasminogen than urokinase.
    Liu JN; Pannell R; Gurewich V
    J Biol Chem; 1992 Aug; 267(22):15289-92. PubMed ID: 1639775
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Occupancy of the cancer cell urokinase receptor (uPAR): effects of acid elution and exogenous uPA on cell surface urokinase (uPA).
    Baker MS; Liang XM; Doe WF
    Biochim Biophys Acta; 1992 Sep; 1117(2):143-52. PubMed ID: 1381963
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Biochemical and thrombolytic properties of a low molecular weight form (comprising Leu144 through Leu411) of recombinant single-chain urokinase-type plasminogen activator.
    Lijnen HR; Nelles L; Holmes WE; Collen D
    J Biol Chem; 1988 Apr; 263(12):5594-8. PubMed ID: 2965704
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Pro-urokinase: a study of its stability in plasma and of a mechanism for its selective fibrinolytic effect.
    Pannell R; Gurewich V
    Blood; 1986 May; 67(5):1215-23. PubMed ID: 3083889
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Neuronal plasminogen activators: cell surface binding sites and involvement in neurite outgrowth.
    Pittman RN; Ivins JK; Buettner HM
    J Neurosci; 1989 Dec; 9(12):4269-86. PubMed ID: 2512375
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Plasminogen activation by single-chain urokinase in functional isolation. A kinetic study.
    Ellis V; Scully MF; Kakkar VV
    J Biol Chem; 1987 Nov; 262(31):14998-5003. PubMed ID: 3667621
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Fragment E-2 from fibrin substantially enhances pro-urokinase-induced Glu-plasminogen activation. A kinetic study using the plasmin-resistant mutant pro-urokinase Ala-158-rpro-UK.
    Liu JN; Gurewich V
    Biochemistry; 1992 Jul; 31(27):6311-7. PubMed ID: 1385727
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Characterization of a recombinant chimeric plasminogen activator composed of a fibrin fragment-D-dimer-specific humanized monoclonal antibody and a truncated single-chain urokinase.
    Vandamme AM; Dewerchin M; Lijnen HR; Bernar H; Bulens F; Nelles L; Collen D
    Eur J Biochem; 1992 Apr; 205(1):139-46. PubMed ID: 1313361
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Plasminogen activation with single-chain urokinase-type plasminogen activator (scu-PA). Studies with active site mutagenized plasminogen (Ser740----Ala) and plasmin-resistant scu-PA (Lys158----Glu).
    Lijnen HR; Van Hoef B; Nelles L; Collen D
    J Biol Chem; 1990 Mar; 265(9):5232-6. PubMed ID: 1969415
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Regulation of human squamous cell carcinoma plasma membrane associated urokinase plasminogen activator by epidermal growth factor.
    Niedbala MJ; Bajetta S; Carbone R; Sartorelli AC
    Cancer Commun; 1990; 2(9):317-24. PubMed ID: 2169831
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Biochemical properties of recombinant mutants of nonglycosylated single chain urokinase-type plasminogen activator.
    Li XK; Lijnen HR; Nelles L; Hu MH; Collen D
    Biochim Biophys Acta; 1992 Sep; 1159(1):37-43. PubMed ID: 1390910
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.