167 related articles for article (PubMed ID: 18284228)
1. A DFT-D investigation of the mechanisms for activation of the wild-type and S810L mutated mineralocorticoid receptor by steroid hormones.
Riley KE; Hobza P
J Phys Chem B; 2008 Mar; 112(10):3157-63. PubMed ID: 18284228
[TBL] [Abstract][Full Text] [Related]
2. Identification of steroid ligands able to inactivate the mineralocorticoid receptor harboring the S810L mutation responsible for a severe form of hypertension.
Pinon GM; Fagart J; Souque A; Auzou G; Vandewalle A; Rafestin-Oblin ME
Mol Cell Endocrinol; 2004 Mar; 217(1-2):181-8. PubMed ID: 15134816
[TBL] [Abstract][Full Text] [Related]
3. Structural basis of spirolactone recognition by the mineralocorticoid receptor.
Huyet J; Pinon GM; Fay MR; Fagart J; Rafestin-Oblin ME
Mol Pharmacol; 2007 Sep; 72(3):563-71. PubMed ID: 17569793
[TBL] [Abstract][Full Text] [Related]
4. A ligand-mediated hydrogen bond network required for the activation of the mineralocorticoid receptor.
Bledsoe RK; Madauss KP; Holt JA; Apolito CJ; Lambert MH; Pearce KH; Stanley TB; Stewart EL; Trump RP; Willson TM; Williams SP
J Biol Chem; 2005 Sep; 280(35):31283-93. PubMed ID: 15967794
[TBL] [Abstract][Full Text] [Related]
5. Crystal structure of a mutant mineralocorticoid receptor responsible for hypertension.
Fagart J; Huyet J; Pinon GM; Rochel M; Mayer C; Rafestin-Oblin ME
Nat Struct Mol Biol; 2005 Jun; 12(6):554-5. PubMed ID: 15908963
[TBL] [Abstract][Full Text] [Related]
6. [Corticosteroid hormones: mechanisms involved in the recognition of aldosterone by mineralocorticoid receptors].
Hellal-Levy C; Fagart J; Souque A; Rafestin-Oblin ME
J Soc Biol; 1999; 193(4-5):355-60. PubMed ID: 10689617
[TBL] [Abstract][Full Text] [Related]
7. Structural and biochemical mechanisms for the specificity of hormone binding and coactivator assembly by mineralocorticoid receptor.
Li Y; Suino K; Daugherty J; Xu HE
Mol Cell; 2005 Aug; 19(3):367-80. PubMed ID: 16061183
[TBL] [Abstract][Full Text] [Related]
8. Structural determinants of ligand binding to the mineralocorticoid receptor.
Huyet J; Pinon GM; Fay MR; Rafestin-Oblin ME; Fagart J
Mol Cell Endocrinol; 2012 Mar; 350(2):187-95. PubMed ID: 21820032
[TBL] [Abstract][Full Text] [Related]
9. The synthetic androgen methyltrienolone (r1881) acts as a potent antagonist of the mineralocorticoid receptor.
Takeda AN; Pinon GM; Bens M; Fagart J; Rafestin-Oblin ME; Vandewalle A
Mol Pharmacol; 2007 Feb; 71(2):473-82. PubMed ID: 17105867
[TBL] [Abstract][Full Text] [Related]
10. Analysis of the hormone-binding domain of steroid receptors using chimeras generated by homologous recombination.
Martinez ED; Pattabiraman N; Danielsen M
Exp Cell Res; 2005 Aug; 308(2):320-33. PubMed ID: 15936754
[TBL] [Abstract][Full Text] [Related]
11. The ligand-dependent interaction of mineralocorticoid receptor with coactivator and corepressor peptides suggests multiple activation mechanisms.
Hultman ML; Krasnoperova NV; Li S; Du S; Xia C; Dietz JD; Lala DS; Welsch DJ; Hu X
Mol Endocrinol; 2005 Jun; 19(6):1460-73. PubMed ID: 15761029
[TBL] [Abstract][Full Text] [Related]
12. Structure-function relationships in the mineralocorticoid receptor.
Pippal JB; Fuller PJ
J Mol Endocrinol; 2008 Dec; 41(6):405-13. PubMed ID: 18805937
[TBL] [Abstract][Full Text] [Related]
13. Cysteines 849 and 942 of human mineralocorticoid receptor are crucial for steroid binding.
Lupo B; Mesnier D; Auzou G
Biochemistry; 1998 Sep; 37(35):12153-9. PubMed ID: 9724527
[TBL] [Abstract][Full Text] [Related]
14. Effect of Water Molecules on the Activating S810L Mutation of the Mineralocorticoid Receptor.
Takedomi K; Ohta M; Ekimoto T; Ikeguchi M
J Chem Inf Model; 2021 Jul; 61(7):3583-3592. PubMed ID: 34228431
[TBL] [Abstract][Full Text] [Related]
15. The severe form of hypertension caused by the activating S810L mutation in the mineralocorticoid receptor is cortisone related.
Rafestin-Oblin ME; Souque A; Bocchi B; Pinon G; Fagart J; Vandewalle A
Endocrinology; 2003 Feb; 144(2):528-33. PubMed ID: 12538613
[TBL] [Abstract][Full Text] [Related]
16. Mixed-model QSAR at the human mineralocorticoid receptor: predicting binding mode and affinity of anabolic steroids.
Peristera O; Spreafico M; Smiesko M; Ernst B; Vedani A
Toxicol Lett; 2009 Sep; 189(3):219-24. PubMed ID: 19523507
[TBL] [Abstract][Full Text] [Related]
17. Ligand-induced conformational changes in the mineralocorticoid receptor analyzed by protease mapping.
Trapp T; Holsboer F
Biochem Biophys Res Commun; 1995 Oct; 215(1):286-91. PubMed ID: 7575603
[TBL] [Abstract][Full Text] [Related]
18. Molecular evolution of the switch for progesterone and spironolactone from mineralocorticoid receptor agonist to antagonist.
Fuller PJ; Yao YZ; Jin R; He S; Martín-Fernández B; Young MJ; Smith BJ
Proc Natl Acad Sci U S A; 2019 Sep; 116(37):18578-18583. PubMed ID: 31439819
[TBL] [Abstract][Full Text] [Related]
19. Activating mineralocorticoid receptor mutation in hypertension exacerbated by pregnancy.
Geller DS; Farhi A; Pinkerton N; Fradley M; Moritz M; Spitzer A; Meinke G; Tsai FT; Sigler PB; Lifton RP
Science; 2000 Jul; 289(5476):119-23. PubMed ID: 10884226
[TBL] [Abstract][Full Text] [Related]
20. Mineralocorticoid receptor binding, structure and function.
Rogerson FM; Brennan FE; Fuller PJ
Mol Cell Endocrinol; 2004 Mar; 217(1-2):203-12. PubMed ID: 15134819
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]