These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
161 related articles for article (PubMed ID: 18285335)
1. Identification of the interaction site within acyl-CoA:cholesterol acyltransferase 2 for the isoform-specific inhibitor pyripyropene A. Das A; Davis MA; Tomoda H; Omura S; Rudel LL J Biol Chem; 2008 Apr; 283(16):10453-60. PubMed ID: 18285335 [TBL] [Abstract][Full Text] [Related]
2. Synthesis and structure-activity relationship of pyripyropene A derivatives as potent and selective acyl-CoA:cholesterol acyltransferase 2 (ACAT2) inhibitors: part 3. Ohtawa M; Yamazaki H; Ohte S; Matsuda D; Ohshiro T; Rudel LL; Ōmura S; Tomoda H; Nagamitsu T Bioorg Med Chem Lett; 2013 Jul; 23(13):3798-801. PubMed ID: 23711919 [TBL] [Abstract][Full Text] [Related]
3. Compared with Acyl-CoA:cholesterol O-acyltransferase (ACAT) 1 and lecithin:cholesterol acyltransferase, ACAT2 displays the greatest capacity to differentiate cholesterol from sitosterol. Temel RE; Gebre AK; Parks JS; Rudel LL J Biol Chem; 2003 Nov; 278(48):47594-601. PubMed ID: 12975367 [TBL] [Abstract][Full Text] [Related]
4. Synthesis and structure-activity relationship of pyripyropene A derivatives as potent and selective acyl-CoA:cholesterol acyltransferase 2 (ACAT2) inhibitors: part 1. Ohtawa M; Yamazaki H; Ohte S; Matsuda D; Ohshiro T; Rudel LL; Omura S; Tomoda H; Nagamitsu T Bioorg Med Chem Lett; 2013 Mar; 23(5):1285-7. PubMed ID: 23369538 [TBL] [Abstract][Full Text] [Related]
5. Isoform-specific inhibitors of ACATs: recent advances and promising developments. Ohshiro T; Tomoda H Future Med Chem; 2011 Dec; 3(16):2039-61. PubMed ID: 22098352 [TBL] [Abstract][Full Text] [Related]
7. Identification of ACAT1- and ACAT2-specific inhibitors using a novel, cell-based fluorescence assay: individual ACAT uniqueness. Lada AT; Davis M; Kent C; Chapman J; Tomoda H; Omura S; Rudel LL J Lipid Res; 2004 Feb; 45(2):378-86. PubMed ID: 14617738 [TBL] [Abstract][Full Text] [Related]
8. A critical role for the histidine residues in the catalytic function of acyl-CoA:cholesterol acyltransferase catalysis: evidence for catalytic difference between ACAT1 and ACAT2. An S; Cho KH; Lee WS; Lee JO; Paik YK; Jeong TS FEBS Lett; 2006 May; 580(11):2741-9. PubMed ID: 16647063 [TBL] [Abstract][Full Text] [Related]
9. Identification of a form of acyl-CoA:cholesterol acyltransferase specific to liver and intestine in nonhuman primates. Anderson RA; Joyce C; Davis M; Reagan JW; Clark M; Shelness GS; Rudel LL J Biol Chem; 1998 Oct; 273(41):26747-54. PubMed ID: 9756918 [TBL] [Abstract][Full Text] [Related]
10. Acyl coenzyme A: cholesterol acyltransferase types 1 and 2: structure and function in atherosclerosis. Rudel LL; Lee RG; Cockman TL Curr Opin Lipidol; 2001 Apr; 12(2):121-7. PubMed ID: 11264983 [TBL] [Abstract][Full Text] [Related]
12. New pyripyropene A derivatives, highly SOAT2-selective inhibitors, improve hypercholesterolemia and atherosclerosis in atherogenic mouse models. Ohshiro T; Ohtawa M; Nagamitsu T; Matsuda D; Yagyu H; Davis MA; Rudel LL; Ishibashi S; Tomoda H J Pharmacol Exp Ther; 2015 Nov; 355(2):299-307. PubMed ID: 26338984 [TBL] [Abstract][Full Text] [Related]
13. Determination of Penicillium griseofulvum-oriented pyripyropene A, a selective inhibitor of acyl-coenzyme A:cholesterol acyltransferase 2, in mouse plasma using liquid chromatography-tandem mass spectrometry and its application to pharmacokinetic studies. Lee KR; Chae SH; Kim MJ; Chae YJ; Lee MY; Lee CW; Kang JS; Yoon WK; Won YS; Lee K; Moon OS; Kim YK; Kim HC Biomed Chromatogr; 2019 Feb; 33(2):e4388. PubMed ID: 30238481 [TBL] [Abstract][Full Text] [Related]
14. Design and synthesis of simple, yet potent and selective non-ring-A pyripyropene A-based inhibitors of acyl-coenzyme A: cholesterol acyltransferase 2 (ACAT2). Zhan Y; Zhang XW; Xiong Y; Li BL; Nan FJ Org Biomol Chem; 2016 Jan; 14(2):747-751. PubMed ID: 26584338 [TBL] [Abstract][Full Text] [Related]
15. ACAT1 and ACAT2 membrane topology segregates a serine residue essential for activity to opposite sides of the endoplasmic reticulum membrane. Joyce CW; Shelness GS; Davis MA; Lee RG; Skinner K; Anderson RA; Rudel LL Mol Biol Cell; 2000 Nov; 11(11):3675-87. PubMed ID: 11071899 [TBL] [Abstract][Full Text] [Related]
16. ACAT2 is localized to hepatocytes and is the major cholesterol-esterifying enzyme in human liver. Parini P; Davis M; Lada AT; Erickson SK; Wright TL; Gustafsson U; Sahlin S; Einarsson C; Eriksson M; Angelin B; Tomoda H; Omura S; Willingham MC; Rudel LL Circulation; 2004 Oct; 110(14):2017-23. PubMed ID: 15451793 [TBL] [Abstract][Full Text] [Related]
17. Molecular structures of human ACAT2 disclose mechanism for selective inhibition. Long T; Liu Y; Li X Structure; 2021 Dec; 29(12):1410-1418.e4. PubMed ID: 34520735 [TBL] [Abstract][Full Text] [Related]
18. Differential expression of ACAT1 and ACAT2 among cells within liver, intestine, kidney, and adrenal of nonhuman primates. Lee RG; Willingham MC; Davis MA; Skinner KA; Rudel LL J Lipid Res; 2000 Dec; 41(12):1991-2001. PubMed ID: 11108732 [TBL] [Abstract][Full Text] [Related]
19. Differential modulation of ACAT1 and ACAT2 transcription and activity by long chain free fatty acids in cultured cells. Seo T; Oelkers PM; Giattina MR; Worgall TS; Sturley SL; Deckelbaum RJ Biochemistry; 2001 Apr; 40(15):4756-62. PubMed ID: 11294643 [TBL] [Abstract][Full Text] [Related]
20. Identification of putative active site residues of ACAT enzymes. Das A; Davis MA; Rudel LL J Lipid Res; 2008 Aug; 49(8):1770-81. PubMed ID: 18480028 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]