BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

156 related articles for article (PubMed ID: 18289105)

  • 1. High yield expression of human BACE constructs in Eschericia coli for refolding, purification, and high resolution diffracting crystal forms.
    Tomasselli AG; Paddock DJ; Emmons TL; Mildner AM; Leone JW; Lull JM; Cialdella JI; Prince DB; Fischer HD; Heinrikson RL; Benson TE
    Protein Pept Lett; 2008; 15(2):131-43. PubMed ID: 18289105
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Large-scale purification of human BACE expressed in mammalian cells and removal of the prosegment with HIV-1 protease to improve crystal diffraction.
    Emmons TL; Shuck ME; Babcock MS; Holloway JS; Leone JW; Durbin JD; Paddock DJ; Prince DB; Heinrikson RL; Fischer HD; Bienkowski MJ; Benson TE; Tomasselli AG
    Protein Pept Lett; 2008; 15(2):119-30. PubMed ID: 18289104
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Large scale refolding and purification of the catalytic domain of human BACE-2 produced in E. coli.
    Emmons TL; Mildner AM; Lull JM; Leone JW; Fischer HD; Heinrikson RL; Tomasselli AG
    Protein Pept Lett; 2009; 16(2):121-31. PubMed ID: 19200034
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Recombinant insect cell expression and purification of human beta-secretase (BACE-1) for X-ray crystallography.
    Bruinzeel W; Yon J; Giovannelli S; Masure S
    Protein Expr Purif; 2002 Oct; 26(1):139-48. PubMed ID: 12356481
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Expression, purification and activity measurement of soluble BACE protein in E.coli.
    Wei XC; Li H; Ji JG; Li R; Ren YF; Feng JH; Hao FY
    Sheng Wu Hua Xue Yu Sheng Wu Wu Li Xue Bao (Shanghai); 2002 Jul; 34(4):498-501. PubMed ID: 12098775
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Comparative studies of active site-ligand interactions among various recombinant constructs of human beta-amyloid precursor protein cleaving enzyme.
    Kopcho LM; Ma J; Marcinkeviciene J; Lai Z; Witmer MR; Cheng J; Yanchunas J; Tredup J; Corbett M; Calambur D; Wittekind M; Paruchuri M; Kothari D; Lee G; Ganguly S; Ramamurthy V; Morin PE; Camac DM; King RW; Lasut AL; Ross OH; Hillman MC; Fish B; Shen K; Dowling RL; Kim YB; Graciani NR; Collins D; Combs AP; George H; Thompson LA; Copeland RA
    Arch Biochem Biophys; 2003 Feb; 410(2):307-16. PubMed ID: 12573291
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The pro domain of beta-secretase does not confer strict zymogen-like properties but does assist proper folding of the protease domain.
    Shi XP; Chen E; Yin KC; Na S; Garsky VM; Lai MT; Li YM; Platchek M; Register RB; Sardana MK; Tang MJ; Thiebeau J; Wood T; Shafer JA; Gardell SJ
    J Biol Chem; 2001 Mar; 276(13):10366-73. PubMed ID: 11266439
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Beta-secretase cleavage of Alzheimer's amyloid precursor protein by the transmembrane aspartic protease BACE.
    Vassar R; Bennett BD; Babu-Khan S; Kahn S; Mendiaz EA; Denis P; Teplow DB; Ross S; Amarante P; Loeloff R; Luo Y; Fisher S; Fuller J; Edenson S; Lile J; Jarosinski MA; Biere AL; Curran E; Burgess T; Louis JC; Collins F; Treanor J; Rogers G; Citron M
    Science; 1999 Oct; 286(5440):735-41. PubMed ID: 10531052
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Crystallization of glycosylated human BACE protease domain expressed in Trichoplusia ni.
    Wang W; Reichert P; Beyer BM; Liu JJ; Lee J; Zhang L; Liu YH; Taremi SS; Le HV; Strickland C
    Biochim Biophys Acta; 2004 May; 1698(2):255-9. PubMed ID: 15134659
    [TBL] [Abstract][Full Text] [Related]  

  • 10. A novel beta-site amyloid precursor protein cleaving enzyme (BACE) isoform regulated by nonsense-mediated mRNA decay and proteasome-dependent degradation.
    Tanahashi H; Tabira T
    Neurosci Lett; 2007 Nov; 428(2-3):103-8. PubMed ID: 17961921
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Development and characterization of a novel membrane assay for full-length BACE-1 at pH 6.0.
    Saric A; Brügge Lz; Müller-Pompalla D; Rysiok T; Ousson S; Permanne B; Quattropani A; Busch M; Beher D; Hussain I
    J Biomol Screen; 2013 Mar; 18(3):277-85. PubMed ID: 23023105
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The disulphide bonds in the catalytic domain of BACE are critical but not essential for amyloid precursor protein processing activity.
    Fischer F; Molinari M; Bodendorf U; Paganetti P
    J Neurochem; 2002 Mar; 80(6):1079-88. PubMed ID: 11953458
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Amyloid precursor protein and BACE function as oligomers.
    Multhaup G
    Neurodegener Dis; 2006; 3(4-5):270-4. PubMed ID: 17047367
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Interaction of the cytosolic domains of sorLA/LR11 with the amyloid precursor protein (APP) and beta-secretase beta-site APP-cleaving enzyme.
    Spoelgen R; von Arnim CA; Thomas AV; Peltan ID; Koker M; Deng A; Irizarry MC; Andersen OM; Willnow TE; Hyman BT
    J Neurosci; 2006 Jan; 26(2):418-28. PubMed ID: 16407538
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Characterization of recombinant, soluble beta-secretase from an insect cell expression system.
    Mallender WD; Yager D; Onstead L; Nichols MR; Eckman C; Sambamurti K; Kopcho LM; Marcinkeviciene J; Copeland RA; Rosenberry TL
    Mol Pharmacol; 2001 Mar; 59(3):619-26. PubMed ID: 11179458
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Human BACE forms dimers and colocalizes with APP.
    Schmechel A; Strauss M; Schlicksupp A; Pipkorn R; Haass C; Bayer TA; Multhaup G
    J Biol Chem; 2004 Sep; 279(38):39710-7. PubMed ID: 15247262
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Modeling of substrate specificity of the Alzheimer's disease amyloid precursor protein beta-secretase.
    Sauder JM; Arthur JW; Dunbrack RL
    J Mol Biol; 2000 Jul; 300(2):241-8. PubMed ID: 10873463
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Purification and cloning of amyloid precursor protein beta-secretase from human brain.
    Sinha S; Anderson JP; Barbour R; Basi GS; Caccavello R; Davis D; Doan M; Dovey HF; Frigon N; Hong J; Jacobson-Croak K; Jewett N; Keim P; Knops J; Lieberburg I; Power M; Tan H; Tatsuno G; Tung J; Schenk D; Seubert P; Suomensaari SM; Wang S; Walker D; Zhao J; McConlogue L; John V
    Nature; 1999 Dec; 402(6761):537-40. PubMed ID: 10591214
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Design and synthesis of novel 3,5-bis-N-(aryl/heteroaryl) carbamoyl-4-aryl-1,4-dihydropyridines as small molecule BACE-1 inhibitors.
    Razzaghi-Asl N; Firuzi O; Hemmateenejad B; Javidnia K; Edraki N; Miri R
    Bioorg Med Chem; 2013 Nov; 21(22):6893-909. PubMed ID: 24113238
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Inhibiting β-secretase activity in Alzheimer's disease cell models with single-chain antibodies specifically targeting APP.
    Boddapati S; Levites Y; Sierks MR
    J Mol Biol; 2011 Jan; 405(2):436-47. PubMed ID: 21073877
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.