BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

299 related articles for article (PubMed ID: 18292755)

  • 1. The autoimmune regulator PHD finger binds to non-methylated histone H3K4 to activate gene expression.
    Org T; Chignola F; Hetényi C; Gaetani M; Rebane A; Liiv I; Maran U; Mollica L; Bottomley MJ; Musco G; Peterson P
    EMBO Rep; 2008 Apr; 9(4):370-6. PubMed ID: 18292755
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The solution structure of the first PHD finger of autoimmune regulator in complex with non-modified histone H3 tail reveals the antagonistic role of H3R2 methylation.
    Chignola F; Gaetani M; Rebane A; Org T; Mollica L; Zucchelli C; Spitaleri A; Mannella V; Peterson P; Musco G
    Nucleic Acids Res; 2009 May; 37(9):2951-61. PubMed ID: 19293276
    [TBL] [Abstract][Full Text] [Related]  

  • 3. PHD finger of autoimmune regulator: an epigenetic link between the histone modifications and tissue-specific antigen expression in thymus.
    Musco G; Peterson P
    Epigenetics; 2008 Nov; 3(6):310-4. PubMed ID: 19011376
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Structure and site-specific recognition of histone H3 by the PHD finger of human autoimmune regulator.
    Chakravarty S; Zeng L; Zhou MM
    Structure; 2009 May; 17(5):670-9. PubMed ID: 19446523
    [TBL] [Abstract][Full Text] [Related]  

  • 5. AIRE-PHD fingers are structural hubs to maintain the integrity of chromatin-associated interactome.
    Gaetani M; Matafora V; Saare M; Spiliotopoulos D; Mollica L; Quilici G; Chignola F; Mannella V; Zucchelli C; Peterson P; Bachi A; Musco G
    Nucleic Acids Res; 2012 Dec; 40(22):11756-68. PubMed ID: 23074189
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Aire employs a histone-binding module to mediate immunological tolerance, linking chromatin regulation with organ-specific autoimmunity.
    Koh AS; Kuo AJ; Park SY; Cheung P; Abramson J; Bua D; Carney D; Shoelson SE; Gozani O; Kingston RE; Benoist C; Mathis D
    Proc Natl Acad Sci U S A; 2008 Oct; 105(41):15878-83. PubMed ID: 18840680
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The biophysical and biochemical properties of the autoimmune regulator (AIRE) protein.
    Perniola R; Musco G
    Biochim Biophys Acta; 2014 Feb; 1842(2):326-37. PubMed ID: 24275490
    [TBL] [Abstract][Full Text] [Related]  

  • 8. AIRE and immunological tolerance: insights from the study of autoimmune polyendocrinopathy candidiasis and ectodermal dystrophy.
    Notarangelo LD; Mazza C; Forino C; Mazzolari E; Buzi F
    Curr Opin Allergy Clin Immunol; 2004 Dec; 4(6):491-6. PubMed ID: 15640689
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Exploring PHD fingers and H3K4me0 interactions with molecular dynamics simulations and binding free energy calculations: AIRE-PHD1, a comparative study.
    Spiliotopoulos D; Spitaleri A; Musco G
    PLoS One; 2012; 7(10):e46902. PubMed ID: 23077531
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Unmodified histone H3K4 and DNA-dependent protein kinase recruit autoimmune regulator to target genes.
    Žumer K; Low AK; Jiang H; Saksela K; Peterlin BM
    Mol Cell Biol; 2012 Apr; 32(8):1354-62. PubMed ID: 22310661
    [TBL] [Abstract][Full Text] [Related]  

  • 11. AIRE functions as an E3 ubiquitin ligase.
    Uchida D; Hatakeyama S; Matsushima A; Han H; Ishido S; Hotta H; Kudoh J; Shimizu N; Doucas V; Nakayama KI; Kuroda N; Matsumoto M
    J Exp Med; 2004 Jan; 199(2):167-72. PubMed ID: 14734522
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Global relevance of Aire binding to hypomethylated lysine-4 of histone-3.
    Koh AS; Kingston RE; Benoist C; Mathis D
    Proc Natl Acad Sci U S A; 2010 Jul; 107(29):13016-21. PubMed ID: 20615959
    [TBL] [Abstract][Full Text] [Related]  

  • 13. NMR structure of the first PHD finger of autoimmune regulator protein (AIRE1). Insights into autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy (APECED) disease.
    Bottomley MJ; Stier G; Pennacchini D; Legube G; Simon B; Akhtar A; Sattler M; Musco G
    J Biol Chem; 2005 Mar; 280(12):11505-12. PubMed ID: 15649886
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Recognition of unmethylated histone H3 lysine 4 links BHC80 to LSD1-mediated gene repression.
    Lan F; Collins RE; De Cegli R; Alpatov R; Horton JR; Shi X; Gozani O; Cheng X; Shi Y
    Nature; 2007 Aug; 448(7154):718-22. PubMed ID: 17687328
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Analysis of the autoimmune regulator gene in patients with autoimmune non-APECED polyendocrinopathies.
    Palma A; Gianchecchi E; Palombi M; Luciano R; Di Carlo P; Crinò A; Cappa M; Fierabracci A
    Genomics; 2013 Sep; 102(3):163-8. PubMed ID: 23643663
    [TBL] [Abstract][Full Text] [Related]  

  • 16. AIRE activated tissue specific genes have histone modifications associated with inactive chromatin.
    Org T; Rebane A; Kisand K; Laan M; Haljasorg U; Andreson R; Peterson P
    Hum Mol Genet; 2009 Dec; 18(24):4699-710. PubMed ID: 19744957
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The autoimmune regulator: a key toward understanding the molecular pathogenesis of autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy.
    Meriluoto T; Halonen M; Pelto-Huikko M; Kangas H; Korhonen J; Kolmer M; Ulmanen I; Eskelin P
    Keio J Med; 2001 Dec; 50(4):225-39. PubMed ID: 11806500
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The autoimmune regulator (AIRE), which is defective in autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy patients, is expressed in human epidermal and follicular keratinocytes and associates with the intermediate filament protein cytokeratin 17.
    Kumar V; Pedroza LA; Mace EM; Seeholzer S; Cotsarelis G; Condino-Neto A; Payne AS; Orange JS
    Am J Pathol; 2011 Mar; 178(3):983-8. PubMed ID: 21356351
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Patient mutation in AIRE disrupts P-TEFb binding and target gene transcription.
    Žumer K; Plemenitaš A; Saksela K; Peterlin BM
    Nucleic Acids Res; 2011 Oct; 39(18):7908-19. PubMed ID: 21724609
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Disruption of immunological tolerance: role of AIRE gene in autoimmunity.
    Rizzi M; Ferrera F; Filaci G; Indiveri F
    Autoimmun Rev; 2006 Feb; 5(2):145-7. PubMed ID: 16431348
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 15.