BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

159 related articles for article (PubMed ID: 18294844)

  • 1. New sulfurated derivatives of valproic acid with enhanced histone deacetylase inhibitory activity.
    Perrino E; Cappelletti G; Tazzari V; Giavini E; Del Soldato P; Sparatore A
    Bioorg Med Chem Lett; 2008 Mar; 18(6):1893-7. PubMed ID: 18294844
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Teratogenic effects mediated by inhibition of histone deacetylases: evidence from quantitative structure activity relationships of 20 valproic acid derivatives.
    Eikel D; Lampen A; Nau H
    Chem Res Toxicol; 2006 Feb; 19(2):272-8. PubMed ID: 16485903
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Increased replication of human cytomegalovirus in retinal pigment epithelial cells by valproic acid depends on histone deacetylase inhibition.
    Michaelis M; Suhan T; Reinisch A; Reisenauer A; Fleckenstein C; Eikel D; Gümbel H; Doerr HW; Nau H; Cinatl J
    Invest Ophthalmol Vis Sci; 2005 Sep; 46(9):3451-7. PubMed ID: 16123451
    [TBL] [Abstract][Full Text] [Related]  

  • 4. S-2-pentyl-4-pentynoic hydroxamic acid and its metabolite s-2-pentyl-4-pentynoic acid in the NMRI-exencephaly-mouse model: pharmacokinetic profiles, teratogenic effects, and histone deacetylase inhibition abilities of further valproic acid hydroxamates and amides.
    Eikel D; Hoffmann K; Zoll K; Lampen A; Nau H
    Drug Metab Dispos; 2006 Apr; 34(4):612-20. PubMed ID: 16415118
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Histone deacetylase inhibitor valproic acid inhibits proliferation and induces apoptosis in KM3 cells via downregulating VEGF receptor.
    Dong XF; Song Q; Li LZ; Zhao CL; Wang LQ
    Neuro Endocrinol Lett; 2007 Dec; 28(6):775-80. PubMed ID: 18063935
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Induction of GRP78 by valproic acid is dependent upon histone deacetylase inhibition.
    Shi Y; Gerritsma D; Bowes AJ; Capretta A; Werstuck GH
    Bioorg Med Chem Lett; 2007 Aug; 17(16):4491-4. PubMed ID: 17566732
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Hepatoprotection and lethality rescue by histone deacetylase inhibitor valproic acid in fatal hemorrhagic shock.
    Gonzales ER; Chen H; Munuve RM; Mehrani T; Nadel A; Koustova E
    J Trauma; 2008 Sep; 65(3):554-65. PubMed ID: 18784568
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Inhibition of histone deacetylase activity on specific embryonic tissues as a new mechanism for teratogenicity.
    Menegola E; Di Renzo F; Broccia ML; Prudenziati M; Minucci S; Massa V; Giavini E
    Birth Defects Res B Dev Reprod Toxicol; 2005 Oct; 74(5):392-8. PubMed ID: 16193500
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Modulation of adhesion and growth of colon and pancreatic cancer cells by the histone deacetylase inhibitor valproic acid.
    Jones J; Bentas W; Blaheta RA; Makarevic J; Hudak L; Wedel S; Probst M; Jonas D; Juengel E
    Int J Mol Med; 2008 Sep; 22(3):293-9. PubMed ID: 18698487
    [TBL] [Abstract][Full Text] [Related]  

  • 10. In vivo anti-myeloma activity and modulation of gene expression profile induced by valproic acid, a histone deacetylase inhibitor.
    Neri P; Tagliaferri P; Di Martino MT; Calimeri T; Amodio N; Bulotta A; Ventura M; Eramo PO; Viscomi C; Arbitrio M; Rossi M; Caraglia M; Munshi NC; Anderson KC; Tassone P
    Br J Haematol; 2008 Nov; 143(4):520-31. PubMed ID: 18986388
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Synthesis and structure-activity relationship of histone deacetylase (HDAC) inhibitors with triazole-linked cap group.
    Chen PC; Patil V; Guerrant W; Green P; Oyelere AK
    Bioorg Med Chem; 2008 May; 16(9):4839-53. PubMed ID: 18397827
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Histone deacetylase inhibitors induce apoptosis, histone hyperacetylation and up-regulation of gene transcription in Schistosoma mansoni.
    Dubois F; Caby S; Oger F; Cosseau C; Capron M; Grunau C; Dissous C; Pierce RJ
    Mol Biochem Parasitol; 2009 Nov; 168(1):7-15. PubMed ID: 19538992
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Zn2+-chelating motif-tethered short-chain fatty acids as a novel class of histone deacetylase inhibitors.
    Lu Q; Yang YT; Chen CS; Davis M; Byrd JC; Etherton MR; Umar A; Chen CS
    J Med Chem; 2004 Jan; 47(2):467-74. PubMed ID: 14711316
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Valproic acid-mediated neuroprotection in intracerebral hemorrhage via histone deacetylase inhibition and transcriptional activation.
    Sinn DI; Kim SJ; Chu K; Jung KH; Lee ST; Song EC; Kim JM; Park DK; Kun Lee S; Kim M; Roh JK
    Neurobiol Dis; 2007 May; 26(2):464-72. PubMed ID: 17398106
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Design, synthesis, and evaluation of biphenyl-4-yl-acrylohydroxamic acid derivatives as histone deacetylase (HDAC) inhibitors.
    Dallavalle S; Cincinelli R; Nannei R; Merlini L; Morini G; Penco S; Pisano C; Vesci L; Barbarino M; Zuco V; De Cesare M; Zunino F
    Eur J Med Chem; 2009 May; 44(5):1900-12. PubMed ID: 19084294
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Anti-leukemic activity of valproic acid and imatinib mesylate on human Ph+ ALL and CML cells in vitro.
    Kircher B; Schumacher P; Petzer A; Hoflehner E; Haun M; Wolf AM; Nachbaur D; Gastl G
    Eur J Haematol; 2009 Jul; 83(1):48-56. PubMed ID: 19226363
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The effects of the histone deacetylase inhibitor valproic acid on cell cycle, growth suppression and apoptosis in multiple myeloma.
    Kaiser M; Zavrski I; Sterz J; Jakob C; Fleissner C; Kloetzel PM; Sezer O; Heider U
    Haematologica; 2006 Feb; 91(2):248-51. PubMed ID: 16461312
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Additive effects of histone deacetylase inhibitors and amphetamine on histone H4 acetylation, cAMP responsive element binding protein phosphorylation and DeltaFosB expression in the striatum and locomotor sensitization in mice.
    Shen HY; Kalda A; Yu L; Ferrara J; Zhu J; Chen JF
    Neuroscience; 2008 Dec; 157(3):644-55. PubMed ID: 18848971
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Neuroendocrine transdifferentiation induced by VPA is mediated by PPARgamma activation and confers resistance to antiblastic therapy in prostate carcinoma.
    Angelucci A; Muzi P; Cristiano L; Millimaggi D; Cimini A; Dolo V; Miano R; Vicentini C; Cerù MP; Bologna M
    Prostate; 2008 May; 68(6):588-98. PubMed ID: 18288684
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Organosulfur derivatives of the HDAC inhibitor valproic acid sensitize human lung cancer cell lines to apoptosis and to cisplatin cytotoxicity.
    Tesei A; Brigliadori G; Carloni S; Fabbri F; Ulivi P; Arienti C; Sparatore A; Del Soldato P; Pasini A; Amadori D; Silvestrini R; Zoli W
    J Cell Physiol; 2012 Oct; 227(10):3389-96. PubMed ID: 22212895
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.